Growth Metrics

Spero Therapeutics (SPRO) Gains from Investment Securities (2016 - 2026)

Quarterly Gains from Investment Securities fell 57.71% to $1.1 million in Q1 2026 from the year-ago period, while the trailing twelve-month figure was $1.1 million through Mar 2026, down 57.71% year-over-year, with the annual reading at $2.4 million for FY2025, 14.72% down from the prior year.

Spero Therapeutics filings provide 11 years of Gains from Investment Securities readings, the most recent being $1.1 million for Q1 2026.

  • Gains from Investment Securities hit $1.1 million in Q1 2026 for Spero Therapeutics, down from $2.4 million in the prior quarter.
  • Across five years, Gains from Investment Securities topped out at $5.8 million in Q1 2022 and bottomed at $35604.0 in Q1 2024.
  • Average Gains from Investment Securities over 5 years is $1.8 million, with a median of $1.1 million recorded in 2026.
  • The largest annual shift saw Gains from Investment Securities crashed 99.11% in 2024 before it soared 7327.76% in 2025.
  • Spero Therapeutics' Gains from Investment Securities stood at $100000.0 in 2022, then skyrocketed by 2111.0% to $2.2 million in 2023, then increased by 27.31% to $2.8 million in 2024, then fell by 14.72% to $2.4 million in 2025, then tumbled by 53.41% to $1.1 million in 2026.
  • Per Business Quant, the three most recent readings for SPRO's Gains from Investment Securities are $1.1 million (Q1 2026), $2.4 million (Q4 2025), and $414417.0 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn -
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn -
5 Akari Therapeutics 605.66 Bn 605.66 Bn -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn
8 Evaxion A 65.12 Bn 65.10 Bn -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn
10 Spero Therapeutics 154.37 Mn 98.24 Mn -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 1.12 Mn
Mar 31, 2026 1.12 Mn
Dec 31, 2025 2.40 Mn
Dec 31, 2025 2.40 Mn
Sep 30, 2025 414,417.00
Sep 30, 2025 414,417.00
Jun 30, 2025 230,932.00
Jun 30, 2025 230,932.00
Mar 31, 2025 2.64 Mn
Mar 31, 2025 2.64 Mn
Dec 31, 2024 2.81 Mn
Dec 31, 2024 2.81 Mn
Sep 30, 2024 35,604.00
Sep 30, 2024 35,604.00
Jun 30, 2024 35,604.00
Jun 30, 2024 35,604.00
Mar 31, 2024 35,604.00
Mar 31, 2024 35,604.00
Dec 31, 2023 2.21 Mn
Dec 31, 2023 2.21 Mn
Sep 30, 2023 1.11 Mn
Sep 30, 2023 1.11 Mn
Jun 30, 2023 3.73 Mn
Jun 30, 2023 3.73 Mn
Mar 31, 2023 4.00 Mn
Mar 31, 2023 4.00 Mn
Dec 31, 2022 100,000.00
Dec 31, 2022 100,000.00
Sep 30, 2022 140,000.00
Sep 30, 2022 140,000.00
Jun 30, 2022 4.62 Mn
Jun 30, 2022 4.62 Mn
Mar 31, 2022 5.78 Mn
Mar 31, 2022 5.78 Mn
Dec 31, 2021 4.89 Mn
Dec 31, 2021 4.89 Mn
Sep 30, 2021 1.51 Mn
Sep 30, 2021 1.51 Mn
Jun 30, 2021 4.58 Mn
Jun 30, 2021 4.58 Mn
Mar 31, 2021 1.02 Mn
Mar 31, 2021 1.02 Mn
Dec 31, 2020 3.68 Mn
Dec 31, 2020 3.68 Mn
Sep 30, 2020 980,828.00
Sep 30, 2020 980,828.00
Jun 30, 2020 82,623.00
Jun 30, 2020 82,623.00
Mar 31, 2020 3.65 Mn
Mar 31, 2020 3.65 Mn
Sep 30, 2019 3.00 Mn
Sep 30, 2019 3.00 Mn
Jun 30, 2019 100,000.00
Jun 30, 2019 100,000.00
Mar 31, 2019 1,000.00
Mar 31, 2019 1,000.00
Dec 31, 2018 2.30 Mn
Dec 31, 2018 2.30 Mn
Sep 30, 2018 476,711.00
Sep 30, 2018 476,711.00
Jun 30, 2018 277,038.00
Jun 30, 2018 277,038.00
Mar 31, 2018 567,319.00
Mar 31, 2018 567,319.00
Dec 31, 2017 2.01 Mn
Dec 31, 2017 2.01 Mn
Sep 30, 2017 243,942.00
Sep 30, 2017 243,942.00
Dec 31, 2016 159,890.00
Dec 31, 2016 159,890.00