Spero Therapeutics (SPRO) Gains from Investment Securities (2016 - 2025)
Spero Therapeutics (SPRO) reported Gains from Investment Securities of $2.4 million for Q4 2025, down 14.72% on a YoY basis from $2.8 million in Q4 2024, and up 479.23% quarter-over-quarter from $414417.0 in Q3 2025.
Spero Therapeutics (SPRO) Gains from Investment Securities (2016 - 2025) Analysis & Trends
Spero Therapeutics has reported Gains from Investment Securities for 10 years, with the latest figure at $2.4 million in Q4 2025.
- For the quarter ending Q4 2025, Gains from Investment Securities fell 14.72% year-over-year to $2.4 million; the trailing twelve-month figure through Mar 2026 stood at $2.3 million (changed 0.0% YoY), and the FY2025 full-year result was $2.4 million, down 14.72% from the prior year.
- Gains from Investment Securities for Q4 2025 stood at $2.4 million, up from $414417.0 in the prior quarter.
- The five-year high for Gains from Investment Securities was $5.8 million in Q1 2022, with the low at $35604.0 in Q1 2024.
- Historically, Gains from Investment Securities has averaged $2.1 million across 5 years, with a median of $1.5 million in 2021.
- Annual changes were most pronounced in 2021 — Gains from Investment Securities jumped 5442.9% — and 2024, when it tumbled 99.11%.
- Spero Therapeutics' Gains from Investment Securities stood at $4.9 million in 2021, then tumbled by 97.96% to $100000.0 in 2022, then soared by 2111.0% to $2.2 million in 2023, then grew by 27.31% to $2.8 million in 2024, then declined by 14.72% to $2.4 million in 2025.
- The last three Gains from Investment Securities figures came in at $2.4 million (Q4 2025), $414417.0 (Q3 2025), and $230932.0 (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - |
| 10 | Spero Therapeutics | 162.39 Mn | 106.26 Mn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 2.40 Mn |
| Dec 31, 2025 | 2.40 Mn |
| Sep 30, 2025 | 414,417.00 |
| Sep 30, 2025 | 414,417.00 |
| Jun 30, 2025 | 230,932.00 |
| Jun 30, 2025 | 230,932.00 |
| Dec 31, 2024 | 2.81 Mn |
| Dec 31, 2024 | 2.81 Mn |
| Sep 30, 2024 | 35,604.00 |
| Sep 30, 2024 | 35,604.00 |
| Jun 30, 2024 | 35,604.00 |
| Jun 30, 2024 | 35,604.00 |
| Mar 31, 2024 | 35,604.00 |
| Mar 31, 2024 | 35,604.00 |
| Dec 31, 2023 | 2.21 Mn |
| Dec 31, 2023 | 2.21 Mn |
| Sep 30, 2023 | 1.11 Mn |
| Sep 30, 2023 | 1.11 Mn |
| Jun 30, 2023 | 3.73 Mn |
| Jun 30, 2023 | 3.73 Mn |