Growth Metrics

Spero Therapeutics (SPRO) Cash & Equivalents (2016 - 2026)

Spero Therapeutics posted quarterly Cash & Equivalents of $56.1 million for Q1 2026, up 14.81% year-on-year from $48.9 million in Q1 2025, and up 39.4% on a QoQ basis from $40.3 million in Q4 2025.

Spero Therapeutics (SPRO) has 11 years of Cash & Equivalents data on file, last reported at $56.1 million in Q1 2026.

  • For the quarter ending Q1 2026, Cash & Equivalents rose 14.81% year-over-year to $56.1 million; the trailing twelve-month figure through Mar 2026 stood at $56.1 million (up 14.81% YoY), and the FY2025 full-year result was $40.3 million, down 23.87% from the prior year.
  • Cash & Equivalents for Q1 2026 stood at $56.1 million, up from $40.3 million in the prior quarter.
  • Across five years, Cash & Equivalents topped out at $109.1 million in Q4 2022 and bottomed at $31.2 million in Q2 2025.
  • The 5-year median for Cash & Equivalents is $63.5 million (2024), against an average of $66.0 million.
  • The widest annual swing landed in 2022, when Cash & Equivalents slumped 55.3%; it then jumped 85.99% in 2023.
  • A 5-year view of Cash & Equivalents shows it stood at $109.1 million in 2022, then sank by 30.04% to $76.3 million in 2023, then sank by 30.71% to $52.9 million in 2024, then fell by 23.87% to $40.3 million in 2025, then soared by 39.4% to $56.1 million in 2026.
  • The last three Cash & Equivalents figures came in at $56.1 million (Q1 2026), $40.3 million (Q4 2025), and $48.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 1.91 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - 32.30 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 286.70 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - 61.46 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 2.77 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 5.49 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 18.44 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 2.96 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 1.71 Bn
10 Spero Therapeutics 162.39 Mn 106.26 Mn - 56.13 Mn

Historic Data

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DateValue
Mar 31, 2026 56.13 Mn
Dec 31, 2025 40.27 Mn
Sep 30, 2025 48.62 Mn
Jun 30, 2025 31.19 Mn
Mar 31, 2025 48.89 Mn
Dec 31, 2024 52.89 Mn
Sep 30, 2024 76.29 Mn
Jun 30, 2024 63.53 Mn
Mar 31, 2024 82.27 Mn
Dec 31, 2023 76.33 Mn
Sep 30, 2023 93.83 Mn
Jun 30, 2023 77.69 Mn
Mar 31, 2023 96.25 Mn
Dec 31, 2022 109.11 Mn
Sep 30, 2022 50.45 Mn
Jun 30, 2022 45.40 Mn
Mar 31, 2022 72.11 Mn
Dec 31, 2021 112.58 Mn
Sep 30, 2021 112.86 Mn
Jun 30, 2021 71.56 Mn
Mar 31, 2021 77.04 Mn
Dec 31, 2020 85.21 Mn
Sep 30, 2020 125.24 Mn
Jun 30, 2020 65.34 Mn
Mar 31, 2020 64.36 Mn
Dec 31, 2019 29.73 Mn
Sep 30, 2019 45.60 Mn
Jun 30, 2019 71.13 Mn
Mar 31, 2019 49.40 Mn
Dec 31, 2018 34.08 Mn
Sep 30, 2018 40.48 Mn
Jun 30, 2018 48.72 Mn
Mar 31, 2018 52.55 Mn
Dec 31, 2017 87.29 Mn
Sep 30, 2017 25.37 Mn
Dec 31, 2016 10.32 Mn
Sep 30, 2016 11.28 Mn