Spero Therapeutics (SPRO) Debt Ratio (2019 - 2026)

Spero Therapeutics' (SPRO) quarterly Debt Ratio came in at 0.0 in Q1 2026, up 16.77% on a QoQ basis from 0.0 in Q4 2025.

Spero Therapeutics (SPRO) Debt Ratio (2019 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has 8 years of Debt Ratio data on file, last reported at 0.0 in Q1 2026.

Quarterly Debt Ratio changed N/A year-over-year to 0.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 0.0 (changed N/A YoY) and the FY2025 annual result came in at 0.0, changed N/A from the prior year.
Debt Ratio grew to 0.0 in Q1 2026, from 0.0 in the prior quarter.
In the past five years, Debt Ratio ranged from a high of 0.0 in Q2 2022 to a low of 0.0 in Q3 2024.
A 5-year average of 0.0 and a median of 0.0 in 2023 frame the typical range for Debt Ratio.
Annual changes were most pronounced in 2022 — Debt Ratio soared 62.24% — and 2024, when it slumped 83.39%.
Tracing SPRO's Debt Ratio over 5 years: stood at 0.0 in 2022, then slumped by 37.99% to 0.0 in 2023, then slumped by 79.84% to 0.0 in 2024, then soared by 1272.81% to 0.0 in 2025, then grew by 16.77% to 0.0 in 2026.
The last three Debt Ratio figures came in at 0.0 (Q1 2026), 0.0 (Q4 2025), and 0.0 (Q3 2024), per Business Quant data.

#	Company	Market Cap	Enterprise Value	Gross Profit (Qtr)	Debt Ratio (Qtr)
1	Vertex Pharmaceuticals	139.13 Bn	131.28 Bn	2.84 Bn	-
2	Regeneron Pharmaceuticals	85.77 Bn	77.77 Bn	3.93 Bn	0.05
3	Argenx Se	64.64 Bn	59.46 Bn	1.37 Bn	-
4	Moderna	58.29 Bn	53.16 Bn	52.00 Mn	0.05
5	BeOne Medicines	41.92 Bn	36.82 Bn	1.53 Bn	0.12
6	Alnylam Pharmaceuticals	31.58 Bn	28.28 Bn	992.69 Mn	-
7	BioNTech SE	28.12 Bn	9.73 Bn	668.28 Mn	0.03
8	Insmed	27.39 Bn	26.22 Bn	358.27 Mn	0.26
9	Royalty Pharma	27.27 Bn	26.43 Bn	-	0.47
10	Spero Therapeutics	70.72 Mn	19.95 Mn	-	0.00

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