Spero Therapeutics (SPRO) Tax Rate (2023 - 2025)
Spero Therapeutics' (SPRO) quarterly Tax Rate came in at 0.88% in Q4 2025, up 68.0% YoY from 0.53% in Q4 2024, and up 334.95% on a QoQ basis from 0.2% in Q4 2024.
Spero Therapeutics (SPRO) Tax Rate (2023 - 2025) Analysis & Trends
Spero Therapeutics (SPRO) has 3 years of Tax Rate data on file, last reported at 0.88% in Q4 2025.
- Quarterly Tax Rate rose 68.0% year-over-year to 0.88% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.22% (up 115.0% YoY) and the FY2025 annual result came in at 4.81%, changed N/A from the prior year.
- Tax Rate improved to 0.88% in Q4 2025, from 0.2% in the prior quarter.
- In the past five years, Tax Rate ranged from a high of 0.88% in Q4 2025 to a low of 224.47% in Q3 2023.
- A 3-year average of 45.16% and a median of 0.65% in 2023 frame the typical range for Tax Rate.
- Annual changes were most pronounced in 2024 — Tax Rate jumped 22268 bps — and 2025, when it soared 68 bps.
- Tracing SPRO's Tax Rate over 3 years: stood at 0.65% in 2023, then soared by 131 bps to 0.2% in 2024, then surged by 335 bps to 0.88% in 2025.
- The last three Tax Rate figures came in at 0.88% (Q4 2025), 0.2% (Q4 2024), and 1.78% (Q3 2024), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Tax Rate (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 20.98% |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 15.11% |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 10.91% |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -1.96% |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 24.15% |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 7.49% |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | -16.71% |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | - |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | 34.12% |
| 10 | Spero Therapeutics | 70.14 Mn | 19.37 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 0.88% |
| Dec 31, 2025 | 0.88% |
| Dec 31, 2025 | 0.88% |
| Dec 31, 2024 | 0.20% |
| Dec 31, 2024 | 0.20% |
| Dec 31, 2024 | 0.20% |
| Sep 30, 2024 | -1.78% |
| Sep 30, 2024 | -1.78% |
| Sep 30, 2024 | -1.78% |
| Dec 31, 2023 | -0.65% |
| Dec 31, 2023 | -0.65% |
| Dec 31, 2023 | -0.65% |
| Sep 30, 2023 | -224.47% |
| Sep 30, 2023 | -224.47% |
| Sep 30, 2023 | -224.47% |