Spero Therapeutics (SPRO) Tax Rate (2023 - 2025)
Spero Therapeutics' (SPRO) quarterly Tax Rate came in at 5.84% in Q4 2025, up 443.0% on a YoY basis from 1.07% in Q4 2024, and up 314.58% quarter-over-quarter from 1.41% in Q4 2024.
Analysis
Spero Therapeutics (SPRO) Tax Rate (2023 - 2025) Analysis & Trends
Spero Therapeutics (SPRO) has reported Tax Rate for 3 consecutive years, with 5.84% the latest figure, recorded in Q4 2025.
- For the quarter ending Q4 2025, Tax Rate rose 443.0% year-over-year to 5.84%; the trailing twelve-month figure through Dec 2025 stood at 21.01% (up 2480.0% YoY), and the FY2025 full-year result was 21.0%, changed N/A from the prior year.
- Tax Rate advanced to 5.84% in Q4 2025 per SPRO's latest filing, from 1.41% in the prior quarter.
- Across five years, Tax Rate topped out at 5.84% in Q4 2025 and bottomed at 222.43% in Q3 2023.
- Historically, Tax Rate has averaged 43.22% across 3 years, with a median of 0.75% in 2023.
- The widest YoY moves for Tax Rate: up 22077 bps in 2024, down 66 bps in 2024.
- Over 3 years, Tax Rate stood at 0.75% in 2023, then jumped by 88 bps to 1.41% in 2024, then soared by 315 bps to 5.84% in 2025.
- According to Business Quant data, Tax Rate over the past three periods registered 5.84%, 1.41%, and 1.66% for Q4 2025, Q4 2024, and Q3 2024 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Tax Rate (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 211.73 Bn | 197.74 Bn | 7.24 Bn | 14.20% |
| 2 | Gilead Sciences | 180.92 Bn | 177.74 Bn | 6.22 Bn | -2.36% |
| 3 | Vertex Pharmaceuticals | 132.16 Bn | 124.30 Bn | 2.84 Bn | 20.98% |
| 4 | Regeneron Pharmaceuticals | 82.89 Bn | 74.90 Bn | 3.93 Bn | 15.11% |
| 5 | Argenx Se | 61.41 Bn | 56.23 Bn | 1.37 Bn | -10.89% |
| 6 | Moderna | 53.99 Bn | 48.85 Bn | 52.00 Mn | -1.96% |
| 7 | Alnylam Pharmaceuticals | 34.48 Bn | 31.18 Bn | 992.69 Mn | 7.49% |
| 8 | Biogen | 31.15 Bn | 29.86 Bn | 1.96 Bn | 26.36% |
| 9 | Roivant Sciences | 30.05 Bn | 30.05 Bn | 1.16 Mn | 1.34% |
| 10 | Spero Therapeutics | 67.82 Mn | 17.05 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 5.84% |
| Dec 31, 2024 | 1.41% |
| Sep 30, 2024 | -1.66% |
| Dec 31, 2023 | 0.75% |
| Sep 30, 2023 | -222.43% |