Spero Therapeutics SPRO
NASDAQ SPRO
$1.17 -0.02 (-1.68%)
At close: Sep 9, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) Tax Rate (2023 - 2025)

Spero Therapeutics' (SPRO) quarterly Tax Rate came in at 5.84% in Q4 2025, up 443.0% on a YoY basis from 1.07% in Q4 2024, and up 314.58% quarter-over-quarter from 1.41% in Q4 2024.

Analysis

Spero Therapeutics (SPRO) Tax Rate (2023 - 2025) Analysis & Trends

Spero Therapeutics (SPRO) has reported Tax Rate for 3 consecutive years, with 5.84% the latest figure, recorded in Q4 2025.

  • For the quarter ending Q4 2025, Tax Rate rose 443.0% year-over-year to 5.84%; the trailing twelve-month figure through Dec 2025 stood at 21.01% (up 2480.0% YoY), and the FY2025 full-year result was 21.0%, changed N/A from the prior year.
  • Tax Rate advanced to 5.84% in Q4 2025 per SPRO's latest filing, from 1.41% in the prior quarter.
  • Across five years, Tax Rate topped out at 5.84% in Q4 2025 and bottomed at 222.43% in Q3 2023.
  • Historically, Tax Rate has averaged 43.22% across 3 years, with a median of 0.75% in 2023.
  • The widest YoY moves for Tax Rate: up 22077 bps in 2024, down 66 bps in 2024.
  • Over 3 years, Tax Rate stood at 0.75% in 2023, then jumped by 88 bps to 1.41% in 2024, then soared by 315 bps to 5.84% in 2025.
  • According to Business Quant data, Tax Rate over the past three periods registered 5.84%, 1.41%, and 1.66% for Q4 2025, Q4 2024, and Q3 2024 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Tax Rate (Qtr)
1 Amgen 211.73 Bn 197.74 Bn 7.24 Bn 14.20%
2 Gilead Sciences 180.92 Bn 177.74 Bn 6.22 Bn -2.36%
3 Vertex Pharmaceuticals 132.16 Bn 124.30 Bn 2.84 Bn 20.98%
4 Regeneron Pharmaceuticals 82.89 Bn 74.90 Bn 3.93 Bn 15.11%
5 Argenx Se 61.41 Bn 56.23 Bn 1.37 Bn -10.89%
6 Moderna 53.99 Bn 48.85 Bn 52.00 Mn -1.96%
7 Alnylam Pharmaceuticals 34.48 Bn 31.18 Bn 992.69 Mn 7.49%
8 Biogen 31.15 Bn 29.86 Bn 1.96 Bn 26.36%
9 Roivant Sciences 30.05 Bn 30.05 Bn 1.16 Mn 1.34%
10 Spero Therapeutics 67.82 Mn 17.05 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 5.84%
Dec 31, 2024 1.41%
Sep 30, 2024 -1.66%
Dec 31, 2023 0.75%
Sep 30, 2023 -222.43%