Spero Therapeutics (SPRO) EBITDA (2016 - 2025)
Spero Therapeutics (SPRO) reported EBITDA of $31.41 million for Q4 2025, compared with -$21.73 million a year earlier.
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Analysis
Spero Therapeutics (SPRO) EBITDA (2016 - 2025) Analysis & Trends
For FY2025, Spero Therapeutics posted EBITDA of $6.31 million.
- By year, EBITDA came in at -$73.36 million in FY2024, $21.85 million in FY2023, -$41.33 million in FY2022 and -$87.33 million in FY2021.
- The Q4 2025 figure ranks as the highest quarterly EBITDA since Q4 2023.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 12.29 Bn |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 9.10 Bn |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 8.33 Bn |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | 999.00 Mn |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | - |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 5.09 Bn |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 4.63 Bn |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | -9.70 Bn |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 5.89 Bn |
| 10 | Spero Therapeutics | 68.40 Mn | -127.38 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 31.41 Mn |
| Sep 30, 2025 | -7.92 Mn |
| Dec 31, 2024 | -21.73 Mn |
| Sep 30, 2024 | -18.59 Mn |
| Jun 30, 2024 | -19.06 Mn |
| Mar 31, 2024 | -13.98 Mn |
| Dec 31, 2023 | 50.57 Mn |
| Sep 30, 2023 | -1.83 Mn |
| Jun 30, 2023 | -12.78 Mn |
| Mar 31, 2023 | -14.11 Mn |
| Dec 31, 2022 | 26.05 Mn |
| Sep 30, 2022 | -11.58 Mn |
| Jun 30, 2022 | -25.79 Mn |
| Mar 31, 2022 | -30.02 Mn |
| Dec 31, 2021 | -27.31 Mn |
| Sep 30, 2021 | -22.38 Mn |
| Jun 30, 2021 | -18.39 Mn |
| Mar 31, 2021 | -19.24 Mn |
| Dec 31, 2020 | -18.57 Mn |
| Sep 30, 2020 | -18.83 Mn |
API Access
Spero Therapeutics EBITDA API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda&ticker=SPRO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();