Growth Metrics

Spero Therapeutics (SPRO) Shares Outstanding (Diluted Average) (2021 - 2026)

Spero Therapeutics posted quarterly Shares Outstanding (Diluted Average) of $57.3 million for Q1 2026, up 3.44% year-on-year from $55.4 million in Q1 2025, and down 2.98% on a QoQ basis from $59.0 million in Q4 2025.

Spero Therapeutics (SPRO) has 6 years of Shares Outstanding (Diluted Average) data on file, last reported at $57.3 million in Q1 2026.

  • For the quarter ending Q1 2026, Shares Outstanding (Diluted Average) rose 3.44% year-over-year to $57.3 million; the trailing twelve-month figure through Mar 2026 stood at $57.3 million (up 3.44% YoY), and the FY2025 full-year result was $59.0 million, up 9.26% from the prior year.
  • Shares Outstanding (Diluted Average) for Q1 2026 stood at $57.3 million, down from $59.0 million in the prior quarter.
  • Across five years, Shares Outstanding (Diluted Average) topped out at $59.0 million in Q4 2025 and bottomed at $32.6 million in Q1 2022.
  • The 5-year median for Shares Outstanding (Diluted Average) is $53.5 million (2024), against an average of $49.8 million.
  • The widest annual swing landed in 2023, when Shares Outstanding (Diluted Average) jumped 61.09%; it then climbed 1.9% in 2024.
  • A 5-year view of Shares Outstanding (Diluted Average) shows it stood at $37.6 million in 2022, then surged by 40.98% to $53.0 million in 2023, then grew by 1.98% to $54.0 million in 2024, then advanced by 9.26% to $59.0 million in 2025, then slipped by 2.98% to $57.3 million in 2026.
  • The last three Shares Outstanding (Diluted Average) figures came in at $57.3 million (Q1 2026), $59.0 million (Q4 2025), and $55.9 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Shares (Diluted Avg.) (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 3.06 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 810.00
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 118.76 Bn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 256.30 Mn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 107.70 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 138.23 Mn
10 Spero Therapeutics 162.39 Mn 106.26 Mn - 57.28 Mn

Historic Data

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DateValue
Mar 31, 2026 57.28 Mn
Dec 31, 2025 59.04 Mn
Sep 30, 2025 55.87 Mn
Jun 30, 2025 55.70 Mn
Mar 31, 2025 55.38 Mn
Dec 31, 2024 54.04 Mn
Sep 30, 2024 54.12 Mn
Jun 30, 2024 53.96 Mn
Mar 31, 2024 53.52 Mn
Dec 31, 2023 52.99 Mn
Sep 30, 2023 52.71 Mn
Jun 30, 2023 52.57 Mn
Mar 31, 2023 52.53 Mn
Dec 31, 2022 37.59 Mn
Sep 30, 2022 33.83 Mn
Jun 30, 2022 32.79 Mn
Mar 31, 2022 32.61 Mn
Dec 31, 2021 30.90 Mn
Sep 30, 2021 30.42 Mn
Jun 30, 2021 29.55 Mn