Spero Therapeutics SPRO
NASDAQ SPRO
$1.17 -0.02 (-1.68%)
At close: Sep 9, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) Price to Sales (2017 - 2026)

Spero Therapeutics' (SPRO) quarterly Price to Sales came in at 525.06 in Q1 2026, up 7562.94% on a YoY basis from 6.85 in Q1 2025, and up 16396.11% quarter-over-quarter from 3.18 in Q4 2025.

Analysis

Spero Therapeutics (SPRO) Price to Sales (2017 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has reported Price to Sales for 10 consecutive years, with 525.06 the latest figure, recorded in Q1 2026.

  • For the quarter ending Q1 2026, Price to Sales rose 7562.94% year-over-year to 525.06; the trailing twelve-month figure through Jun 2026 stood at 2.73 (down 18.49% YoY), and the FY2025 full-year result was 1.97, up 67.89% from the prior year.
  • Price to Sales advanced to 525.06 in Q1 2026 per SPRO's latest filing, from 3.18 in the prior quarter.
  • Across five years, Price to Sales topped out at 525.06 in Q1 2026 and bottomed at 1.06 in Q4 2023.
  • Historically, Price to Sales has averaged 50.32 across 5 years, with a median of 10.0 in 2024.
  • The sharpest annual moves came in 2022 and 2026: Price to Sales slumped 99.27% in 2022, then jumped 7562.94% in 2026.
  • Over 5 years, Price to Sales stood at 1.37 in 2022, then dropped by 22.68% to 1.06 in 2023, then jumped by 252.73% to 3.74 in 2024, then slipped by 14.84% to 3.18 in 2025, then soared by 16396.11% to 525.06 in 2026.
  • According to Business Quant data, Price to Sales over the past three periods registered 525.06, 3.18, and 19.45 for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Amgen 211.73 Bn 197.74 Bn 7.24 Bn
2 Gilead Sciences 180.92 Bn 177.74 Bn 6.22 Bn
3 Vertex Pharmaceuticals 132.16 Bn 124.30 Bn 2.84 Bn
4 Regeneron Pharmaceuticals 82.89 Bn 74.90 Bn 3.93 Bn
5 Argenx Se 61.41 Bn 56.23 Bn 1.37 Bn
6 Moderna 53.99 Bn 48.85 Bn 52.00 Mn
7 Alnylam Pharmaceuticals 34.48 Bn 31.18 Bn 992.69 Mn
8 Biogen 31.15 Bn 29.86 Bn 1.96 Bn
9 Roivant Sciences 30.05 Bn 30.05 Bn 1.16 Mn
10 Spero Therapeutics 67.82 Mn 17.05 Mn -
Historic Data

Historic Data

Download Data
DateValue
Mar 31, 2026 525.06
Dec 31, 2025 3.18
Sep 30, 2025 19.45
Jun 30, 2025 11.48
Mar 31, 2025 6.85
Dec 31, 2024 3.74
Sep 30, 2024 5.40
Jun 30, 2024 6.89
Mar 31, 2024 10.00
Dec 31, 2023 1.06
Sep 30, 2023 2.52
Jun 30, 2023 28.07
Mar 31, 2023 36.84
Dec 31, 2022 1.37
Sep 30, 2022 42.73
Jun 30, 2022 13.04
Mar 31, 2022 137.73
Dec 31, 2021 189.00
Sep 30, 2021 193.60
Jun 30, 2021 80.54