Spero Therapeutics (SPRO) Revenue (2016 - 2026)
Spero Therapeutics (SPRO) reported Revenue of $258000.0 for Q1 2026, down 95.61% on a YoY basis from $5.9 million in Q1 2025, and up 103.51% quarter-over-quarter from -$7.3 million in Q4 2025.
Spero Therapeutics (SPRO) Revenue (2016 - 2026) Analysis & Trends
Spero Therapeutics has reported Revenue for 11 years, with the latest figure at $258000.0 in Q1 2026.
- For the quarter ending Q1 2026, Revenue fell 95.61% year-over-year to $258000.0; the trailing twelve-month figure through Mar 2026 stood at $12.5 million (down 70.21% YoY), and the FY2025 full-year result was $12.6 million, down 73.74% from the prior year.
- Revenue for Q1 2026 stood at $258000.0, up from -$7.3 million in the prior quarter.
- The five-year high for Revenue was $65.5 million in Q4 2023, with the low at -$7.3 million in Q4 2025.
- Historically, Revenue has averaged $9.1 million across 5 years, with a median of $2.7 million in 2023.
- The largest YoY upside for Revenue was 8272.31% in 2025 against a maximum downside of 124.29% in 2025.
- Spero Therapeutics' Revenue stood at $16.8 million in 2022, then soared by 290.72% to $65.5 million in 2023, then sank by 53.84% to $30.3 million in 2024, then tumbled by 124.29% to -$7.3 million in 2025, then surged by 103.51% to $258000.0 in 2026.
- The last three Revenue figures came in at $258000.0 (Q1 2026), -$7.3 million (Q4 2025), and $5.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Revenue (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 5.21 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 306.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 2.99 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Spero Therapeutics | 129.74 Mn | 73.61 Mn | - | 258,000.00 |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 258,000.00 |
| Dec 31, 2025 | -7.35 Mn |
| Sep 30, 2025 | 5.44 Mn |
| Jun 30, 2025 | 14.19 Mn |
| Mar 31, 2025 | 5.87 Mn |
| Dec 31, 2024 | 30.26 Mn |
| Sep 30, 2024 | 65,000.00 |
| Jun 30, 2024 | 5.90 Mn |
| Mar 31, 2024 | 9.27 Mn |
| Dec 31, 2023 | 65.54 Mn |
| Sep 30, 2023 | 218,000.00 |
| Jun 30, 2023 | 2.72 Mn |
| Mar 31, 2023 | 223,000.00 |
| Dec 31, 2022 | 16.78 Mn |
| Sep 30, 2022 | 2.01 Mn |
| Jun 30, 2022 | 1.99 Mn |
| Mar 31, 2022 | 2.07 Mn |
| Dec 31, 2021 | 15.44 Mn |
| Sep 30, 2021 | 708,000.00 |
| Jun 30, 2021 | 2.11 Mn |