Spero Therapeutics SPRO
NASDAQ SPRO
$1.12 -0.05 (-4.27%)
At close: Sep 10, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) Revenue (2016 - 2026)

Spero Therapeutics' (SPRO) quarterly Revenue came in at $258000.0 in Q1 2026, down 95.61% on a YoY basis from $5.9 million in Q1 2025, and down 99.38% quarter-over-quarter from $41.3 million in Q4 2025.

Analysis

Spero Therapeutics (SPRO) Revenue (2016 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has reported Revenue for 11 consecutive years, with $258000.0 the latest figure, recorded in Q1 2026.

  • For the quarter ending Q1 2026, Revenue fell 95.61% year-over-year to $258000.0; the trailing twelve-month figure through Jun 2026 stood at $47.0 million (down 3.25% YoY), and the FY2025 full-year result was $66.8 million, up 39.24% from the prior year.
  • Revenue declined to $258000.0 in Q1 2026 per SPRO's latest filing, from $41.3 million in the prior quarter.
  • Across five years, Revenue topped out at $73.5 million in Q4 2023 and bottomed at $258000.0 in Q1 2026.
  • Historically, Revenue has averaged $16.0 million across 5 years, with a median of $9.3 million in 2024.
  • The sharpest annual moves came in 2022 and 2026: Revenue soared 1628.9% in 2022, then sank 95.61% in 2026.
  • Over 5 years, Revenue stood at $47.4 million in 2022, then jumped by 54.98% to $73.5 million in 2023, then tumbled by 79.54% to $15.0 million in 2024, then jumped by 174.51% to $41.3 million in 2025, then sank by 99.38% to $258000.0 in 2026.
  • According to Business Quant data, Revenue over the past three periods registered $258000.0, $41.3 million, and $5.4 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Revenue (Qtr)
1 Amgen 206.44 Bn 192.45 Bn 7.24 Bn 10.05 Bn
2 Gilead Sciences 179.97 Bn 176.79 Bn 6.22 Bn 7.80 Bn
3 Vertex Pharmaceuticals 130.57 Bn 122.72 Bn 2.84 Bn 3.33 Bn
4 Regeneron Pharmaceuticals 81.63 Bn 73.63 Bn 3.93 Bn 4.29 Bn
5 Argenx Se 60.34 Bn 55.16 Bn 1.37 Bn 1.52 Bn
6 Moderna 54.37 Bn 49.23 Bn 52.00 Mn 145.00 Mn
7 Alnylam Pharmaceuticals 33.07 Bn 29.76 Bn 992.69 Mn 1.29 Bn
8 Biogen 31.84 Bn 30.55 Bn 1.96 Bn 2.74 Bn
9 Roivant Sciences 29.49 Bn 29.49 Bn 1.16 Mn 1.44 Mn
10 Spero Therapeutics 65.50 Mn 14.73 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Mar 31, 2026 258,000.00
Dec 31, 2025 41.30 Mn
Sep 30, 2025 5.44 Mn
Jun 30, 2025 14.19 Mn
Mar 31, 2025 5.87 Mn
Dec 31, 2024 15.04 Mn
Sep 30, 2024 13.47 Mn
Jun 30, 2024 10.20 Mn
Mar 31, 2024 9.27 Mn
Dec 31, 2023 73.52 Mn
Sep 30, 2023 25.47 Mn
Jun 30, 2023 2.72 Mn
Mar 31, 2023 2.07 Mn
Dec 31, 2022 47.44 Mn
Sep 30, 2022 2.01 Mn
Jun 30, 2022 1.99 Mn
Mar 31, 2022 2.07 Mn
Dec 31, 2021 2.74 Mn
Sep 30, 2021 3.06 Mn
Jun 30, 2021 5.15 Mn