Spero Therapeutics (SPRO) Cash from Operations (2016 - 2026)
Spero Therapeutics' Cash from Operations was -$5.36 million in Q2 2026, compared with -$17.69 million a year earlier.
Spero Therapeutics (SPRO) Cash from Operations (2016 - 2026) Analysis & Trends
On a trailing twelve-month basis, Spero Therapeutics' Cash from Operations was $19.58 million through Jun 30, 2026; for FY2025, it was -$12.62 million.
- In earlier years, Cash from Operations was -$23.44 million in FY2024, -$33 million in FY2023, -$7.73 million in FY2022 and -$64.35 million in FY2021.
- Quarterly Cash from Operations has moved between -$28.22 million (Q1 2022) and $44.48 million (Q4 2022) over five years.
- Per Business Quant data, SPRO's Cash from Operations in the three quarters before Q2 2026 was $15.86 million (Q1 2026), -$8.35 million (Q4 2025) and $17.42 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Ops. (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,169.76 Bn | 1,138.35 Bn | 19.71 Bn | 10.69 Bn |
| 2 | Johnson & Johnson | 648.06 Bn | 567.92 Bn | 17.30 Bn | 7.72 Bn |
| 3 | AbbVie | 503.37 Bn | 476.48 Bn | 12.70 Bn | 3.44 Bn |
| 4 | Merck | 365.39 Bn | 319.77 Bn | 12.21 Bn | 5.37 Bn |
| 5 | Novartis Ag | 303.45 Bn | 267.44 Bn | 11.24 Bn | 5.88 Bn |
| 6 | Astrazeneca | 269.03 Bn | 242.72 Bn | 12.86 Bn | 2.87 Bn |
| 7 | Amgen | 242.08 Bn | 197.48 Bn | 7.24 Bn | 4.00 Bn |
| 8 | Gilead Sciences | 194.88 Bn | 169.07 Bn | 6.22 Bn | 3.57 Bn |
| 9 | Pfizer | 172.39 Bn | 119.04 Bn | 10.94 Bn | 835.00 Mn |
| 10 | Spero Therapeutics | 65.50 Mn | -130.28 Mn | - | -5.36 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -5.36 Mn |
| Mar 31, 2026 | 15.86 Mn |
| Dec 31, 2025 | -8.35 Mn |
| Sep 30, 2025 | 17.42 Mn |
| Jun 30, 2025 | -17.69 Mn |
| Mar 31, 2025 | -4.00 Mn |
| Dec 31, 2024 | -23.40 Mn |
| Sep 30, 2024 | 12.76 Mn |
| Jun 30, 2024 | -18.74 Mn |
| Mar 31, 2024 | 5.94 Mn |
| Dec 31, 2023 | -17.49 Mn |
| Sep 30, 2023 | 15.92 Mn |
| Jun 30, 2023 | -18.56 Mn |
| Mar 31, 2023 | -12.85 Mn |
| Dec 31, 2022 | 44.48 Mn |
| Sep 30, 2022 | -957,000.00 |
| Jun 30, 2022 | -23.03 Mn |
| Mar 31, 2022 | -28.22 Mn |
| Dec 31, 2021 | -27.35 Mn |
| Sep 30, 2021 | -4.95 Mn |
Spero Therapeutics Cash from Operations API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=cash-from-operations&ticker=SPRO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "cash-from-operations", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=cash-from-operations&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();