Spero Therapeutics (SPRO) Cash from Operations (2016 - 2026)
Spero Therapeutics posted quarterly Cash from Operations of 15864000.0 for Q1 2026, up 496.4% year-on-year from 2659951.73 in Q1 2025, and up 289.97% on a QoQ basis from 8351000.0 in Q4 2025.
Spero Therapeutics (SPRO) has 11 years of Cash from Operations data on file, last reported at 15864000.0 in Q1 2026.
- For the quarter ending Q1 2026, Cash from Operations rose 496.4% year-over-year to 15864000.0; the trailing twelve-month figure through Mar 2026 stood at 7242000.0 (up 121.69% YoY), and the FY2025 full-year result was 12624000.0, up 46.15% from the prior year.
- Cash from Operations for Q1 2026 stood at 15864000.0, up from 8351000.0 in the prior quarter.
- Across five years, Cash from Operations topped out at 44482000.0 in Q4 2022 and bottomed at 28223000.0 in Q1 2022.
- The 5-year median for Cash from Operations is 8351000.0 (2025), against an average of 3584117.65.
- The widest annual swing landed in 2023, when Cash from Operations jumped 1763.01%; it then sank 167.4% in 2025.
- A 5-year view of Cash from Operations shows it stood at 44482000.0 in 2022, then plunged by 139.33% to 17493000.0 in 2023, then tumbled by 33.77% to 23401000.0 in 2024, then soared by 64.31% to 8351000.0 in 2025, then jumped by 289.97% to 15864000.0 in 2026.
- The last three Cash from Operations figures came in at 15864000.0 (Q1 2026), 8351000.0 (Q4 2025), and 17422000.0 (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Operations (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | -1.67 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -12.20 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.49 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 1.43 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 1.08 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 70.50 Mn |
| 10 | Spero Therapeutics | 162.39 Mn | 106.26 Mn | - | 15.86 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 15.86 Mn |
| Mar 31, 2026 | 15.86 Mn |
| Dec 31, 2025 | -8.35 Mn |
| Dec 31, 2025 | -8.35 Mn |
| Sep 30, 2025 | 17.42 Mn |
| Sep 30, 2025 | 17.42 Mn |
| Jun 30, 2025 | -17.69 Mn |
| Jun 30, 2025 | -17.69 Mn |
| Mar 31, 2025 | -4.00 Mn |
| Mar 31, 2025 | -4.00 Mn |
| Dec 31, 2024 | -23.40 Mn |
| Dec 31, 2024 | -23.40 Mn |
| Sep 30, 2024 | 12.76 Mn |
| Sep 30, 2024 | 12.76 Mn |
| Jun 30, 2024 | -18.74 Mn |
| Jun 30, 2024 | -18.74 Mn |
| Mar 31, 2024 | 5.94 Mn |
| Mar 31, 2024 | 5.94 Mn |
| Dec 31, 2023 | -17.49 Mn |
| Dec 31, 2023 | -17.49 Mn |
| Sep 30, 2023 | 15.92 Mn |
| Sep 30, 2023 | 15.92 Mn |
| Jun 30, 2023 | -18.56 Mn |
| Jun 30, 2023 | -18.56 Mn |
| Mar 31, 2023 | -12.85 Mn |
| Mar 31, 2023 | -12.85 Mn |
| Dec 31, 2022 | 44.48 Mn |
| Dec 31, 2022 | 44.48 Mn |
| Sep 30, 2022 | -957,000.00 |
| Sep 30, 2022 | -957,000.00 |
| Jun 30, 2022 | -23.03 Mn |
| Jun 30, 2022 | -23.03 Mn |
| Mar 31, 2022 | -28.22 Mn |
| Mar 31, 2022 | -28.22 Mn |
| Dec 31, 2021 | -27.35 Mn |
| Dec 31, 2021 | -27.35 Mn |
| Sep 30, 2021 | -4.95 Mn |
| Sep 30, 2021 | -4.95 Mn |
| Jun 30, 2021 | -16.57 Mn |
| Jun 30, 2021 | -16.57 Mn |
| Mar 31, 2021 | -15.48 Mn |
| Mar 31, 2021 | -15.48 Mn |
| Dec 31, 2020 | -16.38 Mn |
| Dec 31, 2020 | -16.38 Mn |
| Sep 30, 2020 | -21.26 Mn |
| Sep 30, 2020 | -21.26 Mn |
| Jun 30, 2020 | -24.90 Mn |
| Jun 30, 2020 | -24.90 Mn |
| Mar 31, 2020 | -23.33 Mn |
| Mar 31, 2020 | -23.33 Mn |
| Dec 31, 2019 | -17.37 Mn |
| Dec 31, 2019 | -17.37 Mn |
| Sep 30, 2019 | -9.66 Mn |
| Sep 30, 2019 | -9.66 Mn |
| Jun 30, 2019 | -12.07 Mn |
| Jun 30, 2019 | -12.07 Mn |
| Mar 31, 2019 | -10.92 Mn |
| Mar 31, 2019 | -10.92 Mn |
| Dec 31, 2018 | -13.51 Mn |
| Dec 31, 2018 | -13.51 Mn |
| Sep 30, 2018 | -5.51 Mn |
| Sep 30, 2018 | -5.51 Mn |
| Jun 30, 2018 | -8.64 Mn |
| Jun 30, 2018 | -8.64 Mn |
| Mar 31, 2018 | -11.96 Mn |
| Mar 31, 2018 | -11.96 Mn |
| Dec 31, 2017 | -12.74 Mn |
| Dec 31, 2017 | -12.74 Mn |
| Sep 30, 2017 | -10.52 Mn |
| Sep 30, 2017 | -10.52 Mn |
| Jun 30, 2017 | -8.88 Mn |
| Jun 30, 2017 | -8.88 Mn |
| Mar 31, 2017 | -6.98 Mn |
| Mar 31, 2017 | -6.98 Mn |
| Dec 31, 2016 | -9.20 Mn |
| Dec 31, 2016 | -9.20 Mn |