Growth Metrics

Spero Therapeutics (SPRO) Equity Average (2017 - 2026)

Spero Therapeutics posted quarterly Equity Average of $56.0 million for Q1 2026, up 40.05% year-on-year from $40.0 million in Q1 2025, and up 30.92% on a QoQ basis from $42.8 million in Q4 2025.

Spero Therapeutics (SPRO) has 10 years of Equity Average data on file, last reported at $56.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Equity Average rose 40.05% year-over-year to $56.0 million; the trailing twelve-month figure through Mar 2026 stood at $56.0 million (up 40.05% YoY), and the FY2025 full-year result was $52.6 million, down 31.29% from the prior year.
  • Equity Average for Q1 2026 stood at $56.0 million, up from $42.8 million in the prior quarter.
  • Across five years, Equity Average topped out at $101.6 million in Q1 2024 and bottomed at $29.7 million in Q3 2025.
  • The 5-year median for Equity Average is $55.8 million (2024), against an average of $58.7 million.
  • The widest annual swing landed in 2022, when Equity Average sank 66.16%; it then soared 58.59% in 2023.
  • A 5-year view of Equity Average shows it stood at $54.2 million in 2022, then surged by 48.13% to $80.3 million in 2023, then plunged by 30.49% to $55.8 million in 2024, then fell by 23.39% to $42.8 million in 2025, then jumped by 30.92% to $56.0 million in 2026.
  • The last three Equity Average figures came in at $56.0 million (Q1 2026), $42.8 million (Q4 2025), and $29.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Equity Avg. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 3.76 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 21.35 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 19.01 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 31.34 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 932.28 Mn
10 Spero Therapeutics 162.39 Mn 106.26 Mn - 55.98 Mn

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 55.98 Mn
Dec 31, 2025 42.76 Mn
Sep 30, 2025 29.66 Mn
Jun 30, 2025 33.32 Mn
Mar 31, 2025 39.97 Mn
Dec 31, 2024 55.82 Mn
Sep 30, 2024 73.00 Mn
Jun 30, 2024 88.37 Mn
Mar 31, 2024 101.57 Mn
Dec 31, 2023 80.30 Mn
Sep 30, 2023 54.24 Mn
Jun 30, 2023 59.81 Mn
Mar 31, 2023 70.39 Mn
Dec 31, 2022 54.21 Mn
Sep 30, 2022 34.20 Mn
Jun 30, 2022 49.20 Mn
Mar 31, 2022 75.38 Mn
Dec 31, 2021 100.09 Mn
Sep 30, 2021 101.07 Mn
Jun 30, 2021 104.55 Mn
Mar 31, 2021 125.44 Mn
Dec 31, 2020 132.41 Mn
Sep 30, 2020 103.25 Mn
Jun 30, 2020 78.07 Mn
Mar 31, 2020 78.50 Mn
Dec 31, 2019 83.80 Mn
Sep 30, 2019 101.35 Mn
Jun 30, 2019 111.50 Mn
Mar 31, 2019 114.59 Mn
Dec 31, 2018 120.70 Mn
Sep 30, 2018 95.61 Mn
Jun 30, 2018 70.28 Mn
Mar 31, 2018 79.93 Mn
Dec 31, 2017 1.56 Mn