Spero Therapeutics (SPRO) Profit After Tax (2016 - 2026)

Spero Therapeutics (SPRO) reported Profit After Tax of -$7.2 million for Q1 2026, up 48.05% on a YoY basis from -$4.9 million in Q1 2025, and down 122.89% quarter-over-quarter from $31.5 million in Q4 2025.

Spero Therapeutics (SPRO) Profit After Tax (2016 - 2026) Analysis & Trends

Spero Therapeutics has reported Profit After Tax for 11 years, with the latest figure at -$7.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Profit After Tax rose 48.05% year-over-year to -$7.2 million; the trailing twelve-month figure through Mar 2026 stood at $15.2 million (up 121.78% YoY), and the FY2025 full-year result was $8.6 million, up 112.5% from the prior year.
  • Profit After Tax for Q1 2026 stood at -$7.2 million, down from $31.5 million in the prior quarter.
  • The five-year high for Profit After Tax was $51.2 million in Q4 2023, with the low at -$32.8 million in Q1 2022.
  • Historically, Profit After Tax has averaged -$5.3 million across 5 years, with a median of -$11.9 million in 2023.
  • Annual changes were most pronounced in 2024 — Profit After Tax slumped 434.38% — and 2025, when it surged 250.58%.
  • Spero Therapeutics' Profit After Tax stood at $26.8 million in 2022, then jumped by 91.27% to $51.2 million in 2023, then sank by 140.82% to -$20.9 million in 2024, then surged by 250.58% to $31.5 million in 2025, then tumbled by 122.89% to -$7.2 million in 2026.
  • The last three Profit After Tax figures came in at -$7.2 million (Q1 2026), $31.5 million (Q4 2025), and -$7.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.94 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 30.90 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.63 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.46 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -753,254.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.03 Bn
9 Abivax 91.96 Bn 91.96 Bn - -56.74 Mn
10 Spero Therapeutics 129.74 Mn 73.61 Mn - -7.20 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -7.20 Mn
Dec 31, 2025 31.47 Mn
Sep 30, 2025 -7.38 Mn
Jun 30, 2025 -1.70 Mn
Mar 31, 2025 -13.87 Mn
Dec 31, 2024 -20.90 Mn
Sep 30, 2024 -17.10 Mn
Jun 30, 2024 -17.86 Mn
Mar 31, 2024 -12.67 Mn
Dec 31, 2023 51.21 Mn
Sep 30, 2023 -3.20 Mn
Jun 30, 2023 -11.91 Mn
Mar 31, 2023 -13.27 Mn
Dec 31, 2022 26.77 Mn
Sep 30, 2022 -11.68 Mn
Jun 30, 2022 -28.68 Mn
Mar 31, 2022 -32.83 Mn
Dec 31, 2021 -29.28 Mn
Sep 30, 2021 -22.52 Mn
Jun 30, 2021 -18.57 Mn