Spero Therapeutics SPRO
NASDAQ SPRO
$1.22 +0.01 (+0.83%)
At close: Aug 21, 2026 · 4:00 PM EDT

Spero Therapeutics (SPRO) Profit After Tax (2016 - 2026)

Spero Therapeutics' (SPRO) quarterly Profit After Tax came in at -$7.2 million in Q1 2026, up 48.2% YoY from -$4.9 million in Q1 2025, and down 122.82% on a QoQ basis from $31.5 million in Q4 2025.

Spero Therapeutics (SPRO) Profit After Tax (2016 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has 11 years of Profit After Tax data on file, last reported at -$7.2 million in Q1 2026.

  • Quarterly Profit After Tax rose 48.2% year-over-year to -$7.2 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $15.2 million (up 121.85% YoY) and the FY2025 annual result came in at $8.6 million, up 112.54% from the prior year.
  • Profit After Tax declined to -$7.2 million in Q1 2026, from $31.5 million in the prior quarter.
  • In the past five years, Profit After Tax ranged from a high of $51.2 million in Q4 2023 to a low of -$32.8 million in Q1 2022.
  • A 5-year average of -$5.3 million and a median of -$11.9 million in 2023 frame the typical range for Profit After Tax.
  • Annual changes were most pronounced in 2024 — Profit After Tax sank 433.54% — and 2025, when it surged 251.03%.
  • Tracing SPRO's Profit After Tax over 5 years: stood at $26.8 million in 2022, then surged by 91.18% to $51.2 million in 2023, then sank by 140.79% to -$20.9 million in 2024, then surged by 251.03% to $31.5 million in 2025, then sank by 122.82% to -$7.2 million in 2026.
  • The last three Profit After Tax figures came in at -$7.2 million (Q1 2026), $31.5 million (Q4 2025), and -$7.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -782.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 237.01 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 164.49 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -355.03 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -16.62 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 81.49 Mn
10 Spero Therapeutics 70.72 Mn 19.95 Mn - -9.55 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -9.55 Mn
Mar 31, 2026 -7.20 Mn
Dec 31, 2025 31.55 Mn
Sep 30, 2025 -7.40 Mn
Jun 30, 2025 -1.70 Mn
Mar 31, 2025 -13.90 Mn
Dec 31, 2024 -20.89 Mn
Sep 30, 2024 -17.10 Mn
Jun 30, 2024 -17.90 Mn
Mar 31, 2024 -12.70 Mn
Dec 31, 2023 51.21 Mn
Sep 30, 2023 -3.21 Mn
Jun 30, 2023 -11.91 Mn
Mar 31, 2023 -13.27 Mn
Dec 31, 2022 26.78 Mn
Sep 30, 2022 -11.68 Mn
Jun 30, 2022 -28.68 Mn
Mar 31, 2022 -32.83 Mn
Dec 31, 2021 -29.24 Mn
Sep 30, 2021 -22.52 Mn