Spero Therapeutics (SPRO) Change in Cash (2016 - 2026)
Spero Therapeutics (SPRO) reported Change in Cash of -$5.36 million for Q2 2026, compared with -$17.69 million a year earlier.
Spero Therapeutics (SPRO) Change in Cash (2016 - 2026) Analysis & Trends
Over the twelve months ended Jun 30, 2026, Spero Therapeutics' Change in Cash came in at $19.58 million; for FY2025, it came in at -$12.62 million.
- By year, Change in Cash came in at -$23.44 million in FY2024, -$32.77 million in FY2023, -$3.48 million in FY2022 and $27.38 million in FY2021 (-50.7%).
- Five-year quarterly Change in Cash spans a low of -$40.47 million in Q1 2022 and a high of $58.66 million in Q4 2022.
- Per Business Quant data, the three quarters before Q2 2026 came in at $15.86 million (Q1 2026), -$8.35 million (Q4 2025) and $17.42 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | -4.07 Bn |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | -3.51 Bn |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 4.21 Bn |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 2.76 Bn |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 3.04 Bn |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | -799.00 Mn |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 3.26 Bn |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 845.00 Mn |
| 10 | Spero Therapeutics | 58.73 Mn | -137.06 Mn | - | -5.36 Mn |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -5.36 Mn |
| Mar 31, 2026 | 15.86 Mn |
| Dec 31, 2025 | -8.35 Mn |
| Sep 30, 2025 | 17.42 Mn |
| Jun 30, 2025 | -17.69 Mn |
| Mar 31, 2025 | -4.00 Mn |
| Dec 31, 2024 | -23.40 Mn |
| Sep 30, 2024 | 12.76 Mn |
| Jun 30, 2024 | -18.74 Mn |
| Mar 31, 2024 | 5.94 Mn |
| Dec 31, 2023 | -17.49 Mn |
| Sep 30, 2023 | 16.14 Mn |
| Jun 30, 2023 | -18.56 Mn |
| Mar 31, 2023 | -12.85 Mn |
| Dec 31, 2022 | 58.66 Mn |
| Sep 30, 2022 | 5.05 Mn |
| Jun 30, 2022 | -26.71 Mn |
| Mar 31, 2022 | -40.47 Mn |
| Dec 31, 2021 | -275,000.00 |
| Sep 30, 2021 | 41.30 Mn |
Spero Therapeutics Change in Cash API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=change-in-cash&ticker=SPRO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "change-in-cash", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=change-in-cash&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();