Growth Metrics

Spero Therapeutics (SPRO) Non Operating Income (2016 - 2026)

Spero Therapeutics posted quarterly Non Operating Income of -$1000.0 for Q1 2026, down 100.12% year-on-year from $865000.0 in Q1 2025, and up 99.95% on a QoQ basis from -$2.1 million in Q4 2025.

Spero Therapeutics (SPRO) has 11 years of Non Operating Income data on file, last reported at -$1000.0 in Q1 2026.

  • For the quarter ending Q1 2026, Non Operating Income fell 100.12% year-over-year to -$1000.0; the trailing twelve-month figure through Mar 2026 stood at -$859000.0 (up 45.29% YoY), and the FY2025 full-year result was $7000.0, down 88.33% from the prior year.
  • Non Operating Income for Q1 2026 stood at -$1000.0, up from -$2.1 million in the prior quarter.
  • Across five years, Non Operating Income topped out at $1.2 million in Q2 2024 and bottomed at -$3.6 million in Q4 2024.
  • The 5-year median for Non Operating Income is -$2000.0 (2023), against an average of -$170470.6.
  • The widest annual swing landed in 2022, when Non Operating Income sank 8573.33%; it then soared 11722.22% in 2023.
  • A 5-year view of Non Operating Income shows it stood at -$9000.0 in 2022, then jumped by 11722.22% to $1.0 million in 2023, then slumped by 444.93% to -$3.6 million in 2024, then jumped by 40.8% to -$2.1 million in 2025, then surged by 99.95% to -$1000.0 in 2026.
  • The last three Non Operating Income figures came in at -$1000.0 (Q1 2026), -$2.1 million (Q4 2025), and $534000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Non Op. Inc. (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 444,000.00
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn -
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 201.20 Mn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -46.98 Mn
10 Spero Therapeutics 162.39 Mn 106.26 Mn - -1,000.00

Historic Data

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DateValue
Mar 31, 2026 -1,000.00
Dec 31, 2025 -2.14 Mn
Sep 30, 2025 534,000.00
Jun 30, 2025 744,000.00
Mar 31, 2025 865,000.00
Dec 31, 2024 -3.61 Mn
Sep 30, 2024 -26,000.00
Jun 30, 2024 1.20 Mn
Mar 31, 2024 -14,000.00
Dec 31, 2023 1.05 Mn
Sep 30, 2023 -10,000.00
Jun 30, 2023 976,000.00
Mar 31, 2023 -2,000.00
Dec 31, 2022 -9,000.00
Sep 30, 2022 159,000.00
Jun 30, 2022 -2.60 Mn
Mar 31, 2022 -13,000.00
Dec 31, 2021 -78,000.00
Sep 30, 2021 3,000.00
Jun 30, 2021 -30,000.00
Mar 31, 2021 -118,000.00
Dec 31, 2020 563,000.00
Sep 30, 2020 84,000.00
Jun 30, 2020 889,000.00
Mar 31, 2020 -437,000.00
Dec 31, 2019 354,000.00
Sep 30, 2019 268,000.00
Jun 30, 2019 135,000.00
Mar 31, 2019 385,000.00
Dec 31, 2018 -616,000.00
Sep 30, 2018 472,000.00
Jun 30, 2018 15,000.00
Mar 31, 2018 172,000.00
Dec 31, 2017 132,000.00
Sep 30, 2017 122,000.00
Jun 30, 2017 402,000.00
Mar 31, 2017 1.19 Mn
Dec 31, 2016 613,000.00
Sep 30, 2016 -4,000.00