Growth Metrics

Spero Therapeutics (SPRO) EBT Margin (2016 - 2025)

Spero Therapeutics' EBT Margin history spans 10 years, with the latest figure at 67.59% for Q4 2025.

  • For Q4 2025, EBT Margin rose 3064836.0% year-over-year to 67.59%; the TTM value through Dec 2025 reached 12.58%, up 28013.0%, while the annual FY2025 figure was 18.77%, 1722389.0% up from the prior year.
  • EBT Margin reached 67.59% in Q4 2025 per SPRO's latest filing, up from 135.69% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 220.43% in Q4 2021 to a low of 30580.77% in Q4 2024.
  • Average EBT Margin over 5 years is 2889.03%, with a median of 250.26% recorded in 2021.
  • Peak YoY movement for EBT Margin: soared 3518228bps in 2021, then tumbled -3065371bps in 2024.
  • A 5-year view of EBT Margin shows it stood at 220.43% in 2021, then dropped by -14bps to 189.0% in 2022, then crashed by -61bps to 72.94% in 2023, then tumbled by -42028bps to 30580.77% in 2024, then surged by 100bps to 67.59% in 2025.
  • Per Business Quant, the three most recent readings for SPRO's EBT Margin are 67.59% (Q4 2025), 135.69% (Q3 2025), and 14.44% (Q2 2025).