Spero Therapeutics SPRO
NASDAQ SPRO
$1.18 -0.04 (-3.28%)
As of: Oct 21, 2026 · 3:49 PM EDT

Spero Therapeutics (SPRO) Operating Income (2016 - 2026)

Updated

Spero Therapeutics' Operating Income came in at -$9.93 million for Q2 2026, compared with -$2.44 million a year earlier.

Analysis

Spero Therapeutics (SPRO) Operating Income (2016 - 2026) Analysis & Trends

Over the trailing twelve months to Jun 30, 2026, Spero Therapeutics reported Operating Income of $6.03 million; for FY2025, it was $6.31 million.

  • Going back by year, Operating Income was -$73.36 million in FY2024, $21.48 million in FY2023, -$42.2 million in FY2022 and -$87.97 million in FY2021.
  • The Q2 2026 figure represents the lowest quarterly Operating Income since Q1 2025.
  • Business Quant data shows SPRO's Operating Income at -$7.54 million (Q1 2026), $31.41 million (Q4 2025) and -$7.92 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Eli Lilly 1,138.83 Bn 1,107.41 Bn 19.71 Bn 11.75 Bn
2 Johnson & Johnson 618.88 Bn 537.41 Bn 17.26 Bn 7.14 Bn
3 AbbVie 502.93 Bn 476.04 Bn 12.70 Bn 6.43 Bn
4 Merck 369.61 Bn 323.99 Bn 12.21 Bn -584.00 Mn
5 Novartis Ag 298.70 Bn 262.69 Bn 11.24 Bn 4.75 Bn
6 Astrazeneca 261.35 Bn 235.03 Bn 12.86 Bn 3.16 Bn
7 Amgen 237.59 Bn 192.99 Bn 7.24 Bn 3.51 Bn
8 Gilead Sciences 191.60 Bn 165.79 Bn 6.22 Bn -10.39 Bn
9 Pfizer 170.23 Bn 116.88 Bn 10.94 Bn 4.27 Bn
10 Spero Therapeutics 68.40 Mn -127.38 Mn - -9.93 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -9.93 Mn
Mar 31, 2026 -7.54 Mn
Dec 31, 2025 31.41 Mn
Sep 30, 2025 -7.92 Mn
Jun 30, 2025 -2.44 Mn
Mar 31, 2025 -14.73 Mn
Dec 31, 2024 -21.73 Mn
Sep 30, 2024 -18.59 Mn
Jun 30, 2024 -19.06 Mn
Mar 31, 2024 -13.98 Mn
Dec 31, 2023 50.53 Mn
Sep 30, 2023 -1.93 Mn
Jun 30, 2023 -12.89 Mn
Mar 31, 2023 -14.23 Mn
Dec 31, 2022 25.92 Mn
Sep 30, 2022 -11.83 Mn
Jun 30, 2022 -26.08 Mn
Mar 31, 2022 -30.21 Mn
Dec 31, 2021 -27.50 Mn
Sep 30, 2021 -22.52 Mn
API Access

Spero Therapeutics Operating Income API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=operating-income&ticker=SPRO&period=max&api_key=YOUR_API_KEY