Spero Therapeutics SPRO
NASDAQ SPRO
$1.24 +0.02 (+2.07%)
As of: Aug 21, 2026 · 11:35 AM EDT

Spero Therapeutics (SPRO) Retained Earnings (2016 - 2026)

Spero Therapeutics' (SPRO) quarterly Retained Earnings came in at -$458.3 million in Q1 2026, up 3.21% YoY from -$444.0 million in Q1 2025, and down 1.6% on a QoQ basis from -$451.1 million in Q4 2025.

Spero Therapeutics (SPRO) Retained Earnings (2016 - 2026) Analysis & Trends

Spero Therapeutics (SPRO) has 11 years of Retained Earnings data on file, last reported at -$458.3 million in Q1 2026.

  • Quarterly Retained Earnings rose 3.21% year-over-year to -$458.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$458.3 million (up 3.21% YoY) and the FY2025 annual result came in at -$451.1 million, up 1.86% from the prior year.
  • Retained Earnings fell to -$458.3 million in Q1 2026, from -$451.1 million in the prior quarter.
  • In the past five years, Retained Earnings ranged from a high of -$391.1 million in Q4 2023 to a low of -$482.6 million in Q3 2025.
  • A 5-year average of -$439.2 million and a median of -$440.6 million in 2022 frame the typical range for Retained Earnings.
  • Annual changes were most pronounced in 2022 — Retained Earnings plunged 34.74% — and 2023, when it climbed 5.51%.
  • Tracing SPRO's Retained Earnings over 5 years: stood at -$413.9 million in 2022, then rose by 5.51% to -$391.1 million in 2023, then retreated by 17.53% to -$459.6 million in 2024, then grew by 1.86% to -$451.1 million in 2025, then retreated by 1.6% to -$458.3 million in 2026.
  • The last three Retained Earnings figures came in at -$458.3 million (Q1 2026), -$451.1 million (Q4 2025), and -$482.6 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Vertex Pharmaceuticals 139.76 Bn 131.91 Bn 2.84 Bn 15.69 Bn
2 Regeneron Pharmaceuticals 86.51 Bn 78.51 Bn 3.93 Bn 37.62 Bn
3 Argenx Se 65.74 Bn 60.56 Bn 1.37 Bn 558.00 Mn
4 Moderna 59.39 Bn 54.26 Bn 52.00 Mn 5.10 Bn
5 BeOne Medicines 42.24 Bn 37.15 Bn 1.53 Bn 13.05 Bn
6 Alnylam Pharmaceuticals 31.78 Bn 28.47 Bn 992.69 Mn -6.33 Bn
7 BioNTech SE 28.65 Bn 10.26 Bn 668.28 Mn 20.91 Bn
8 Insmed 27.58 Bn 26.42 Bn 358.27 Mn 6.57 Bn
9 Royalty Pharma 27.22 Bn 26.39 Bn - 4.38 Bn
10 Spero Therapeutics 71.59 Mn 20.82 Mn - -467.82 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -467.82 Mn
Mar 31, 2026 -458.30 Mn
Dec 31, 2025 -451.07 Mn
Sep 30, 2025 -482.59 Mn
Jun 30, 2025 -475.20 Mn
Mar 31, 2025 -473.50 Mn
Dec 31, 2024 -459.64 Mn
Sep 30, 2024 -438.75 Mn
Jun 30, 2024 -421.60 Mn
Mar 31, 2024 -403.70 Mn
Dec 31, 2023 -391.07 Mn
Dec 31, 2022 -413.88 Mn
Sep 30, 2022 -440.65 Mn
Mar 31, 2022 -400.30 Mn
Dec 31, 2021 -367.46 Mn
Sep 30, 2021 -338.22 Mn
Jun 30, 2021 -315.70 Mn
Mar 31, 2021 -297.10 Mn
Dec 31, 2020 -277.71 Mn
Sep 30, 2020 -259.10 Mn