As of March 23, 2026, the three largest insider holders of SPRO are Capital Management, Llc Aquilo (TenPercentOwner, 3.42Mn shares), Sath Shukla (Ceo President, 1.74Mn shares), Esther Rajavelu (See Remarks, 1.01Mn shares).
| Holder | Position | Shares (Direct) | Shares (Indirect) | Report Date |
|---|---|---|---|---|
| Capital Management, Llc Aquilo | 0 | 3,419,435 | 26 Sep, 2022 | |
| Sath Shukla | Ceo President | 1,736,883 | 0 | 05 Feb, 2025 |
| Esther Rajavelu | See Remarks | 1,012,091 | 0 | 09 Feb, 2026 |
| Kamal Hamed | Chief Medical Officer | 788,117 | 0 | 05 Feb, 2024 |
| Timothy Keutzer | Chief Operating Officer | 742,506 | 0 | 09 Feb, 2026 |
| Ankit Mahadevia | 703,294 | 0 | 02 Sep, 2025 | |
| Cynthia Smith | 75,000 | 0 | 12 Jun, 2025 | |
| Kathleen Tregoning | 75,000 | 0 | 12 Jun, 2025 | |
| Frank E Thomas | 75,000 | 0 | 12 Jun, 2025 | |
| Patrick V.J.J. Vink | 75,000 | 0 | 12 Jun, 2025 | |
| Scott Thomas Jackson | 75,000 | 0 | 12 Jun, 2025 | |
| Cristina Larkin | Chief Operating Officer | 63,581 | 0 | 03 Feb, 2022 |
| David A. Melnick | Chief Medical Officer | 62,081 | 0 | 03 Feb, 2022 |
* Please note that the shares above only reflect shares from the fund portfolio and the institutional portfolio. Shares from the personal portfolio are excluded from this Institutional Ownership Page. See these insiders' latest transactions here on Insider Page.
| Transaction Date | Insider Name | Security Class | Transaction Type | Shares Traded | Price | Shares Remaining | Ownership | Code |
|---|---|---|---|---|---|---|---|---|
| 06 Feb, 2026 | Timothy Keutzer | Common Stock | D | 18,652 | $2.36 | 742,506 | D | S |
| 06 Feb, 2026 | Esther Rajavelu | Common Stock | D | 37,101 | $2.36 | 1,062,907 | D | S |
| 06 Feb, 2026 | Esther Rajavelu | Common Stock | D | 50,816 | $2.36 | 1,012,091 | D | S |
| 02 Feb, 2026 | Esther Rajavelu | Common Stock | A | 249,000 | $0.00 | 1,118,450 | D | A |
| 02 Feb, 2026 | Timothy Keutzer | Common Stock | A | 68,000 | $0.00 | 807,744 | D | A |
| 02 Feb, 2026 | Timothy Keutzer | Common Stock | D | 18,891 | $2.20 | 788,853 | D | S |
| 02 Feb, 2026 | Esther Rajavelu | Common Stock | D | 18,442 | $2.20 | 1,100,008 | D | S |
| 02 Feb, 2026 | Esther Rajavelu | Stock Option (Right to Buy) | A | 498,000 | $0.00 | 498,000 | D | A |
| 03 Feb, 2026 | Timothy Keutzer | Common Stock | D | 24,224 | $2.14 | 764,629 | D | S |
| 04 Feb, 2026 | Timothy Keutzer | Common Stock | D | 3,471 | $2.24 | 761,158 | D | S |
| 02 Feb, 2026 | Timothy Keutzer | Stock Option (Right to Buy) | A | 137,000 | $0.00 | 137,000 | D | A |
| 07 Nov, 2025 | Esther Rajavelu | Common Stock | D | 40,270 | $2.37 | 869,450 | D | S |
| 28 Aug, 2025 | Ankit Mahadevia | Common Stock | D | 6,572 | $1.97 | 703,294 | D | S |
| 28 Aug, 2025 | Timothy Keutzer | Common Stock | D | 1,695 | $1.97 | 739,744 | D | S |
| 12 Jun, 2025 | Patrick V.J.J. Vink | Common Stock | A | 20,000 | $0.00 | 75,000 | D | A |
| 12 Jun, 2025 | Ankit Mahadevia | Common Stock | A | 20,000 | $0.00 | 709,866 | D | A |
| 12 Jun, 2025 | Cynthia Smith | Common Stock | A | 20,000 | $0.00 | 75,000 | D | A |
| 12 Jun, 2025 | Scott Thomas Jackson | Common Stock | A | 20,000 | $0.00 | 75,000 | D | A |
| 12 Jun, 2025 | Frank E Thomas | Common Stock | A | 20,000 | $0.00 | 75,000 | D | A |
| 12 Jun, 2025 | Kathleen Tregoning | Common Stock | A | 20,000 | $0.00 | 75,000 | D | A |