Spero Therapeutics (SPRO) Enterprise Value (2017 - 2026)
Spero Therapeutics (SPRO) recorded Enterprise Value of $77.73 million in Q2 2026, down 41.0% from $131.75 million a year earlier and down 2.0% from the prior quarter.
Powered by 
Analysis
Spero Therapeutics (SPRO) Enterprise Value (2017 - 2026) Analysis & Trends
On a TTM basis, Spero Therapeutics' Enterprise Value came in at -$67.28 million as of Jun 30, 2026; for FY2025, it was $91.18 million.
- Annual Enterprise Value has a five-year compound annual growth rate of -21.6% (FY2020 to FY2025).
- Across earlier years, Enterprise Value came in at $3.34 million in FY2024 (+112.0%), $1.58 million in FY2023, -$44.08 million in FY2022 and $372.22 million in FY2021 (+21.2%).
- Quarterly Enterprise Value has ranged from -$44.08 million in Q4 2022 to $469.76 million in Q3 2021 over the past five years.
- Per Business Quant, the preceding three quarters came in at $79.34 million (Q1 2026), $91.18 million (Q4 2025) and $57.25 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn |
| 10 | Spero Therapeutics | 68.40 Mn | -127.38 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 77.73 Mn |
| Mar 31, 2026 | 79.34 Mn |
| Dec 31, 2025 | 91.18 Mn |
| Sep 30, 2025 | 57.25 Mn |
| Jun 30, 2025 | 131.75 Mn |
| Mar 31, 2025 | -8.64 Mn |
| Dec 31, 2024 | 3.34 Mn |
| Sep 30, 2024 | -3.51 Mn |
| Jun 30, 2024 | 6.68 Mn |
| Mar 31, 2024 | 10.38 Mn |
| Dec 31, 2023 | 1.58 Mn |
| Sep 30, 2023 | -29.70 Mn |
| Jun 30, 2023 | -1.46 Mn |
| Mar 31, 2023 | -20.02 Mn |
| Dec 31, 2022 | -44.08 Mn |
| Sep 30, 2022 | 35.27 Mn |
| Jun 30, 2022 | -19.45 Mn |
| Mar 31, 2022 | 163.01 Mn |
| Dec 31, 2021 | 372.22 Mn |
| Sep 30, 2021 | 469.76 Mn |
API Access
Spero Therapeutics Enterprise Value API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=enterprise-value&ticker=SPRO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "enterprise-value", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=enterprise-value&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();