Spero Therapeutics (SPRO) Return on Equity (2017 - 2026)
Spero Therapeutics (SPRO) reported Return on Equity of 0.0% for Q1 2026, up 2.0% on a YoY basis from 0.0% in Q1 2025, and up 35.82% quarter-over-quarter from 0.0% in Q4 2025.
Spero Therapeutics (SPRO) Return on Equity (2017 - 2026) Analysis & Trends
Spero Therapeutics has reported Return on Equity for 10 years, with the latest figure at 0.0% in Q1 2026.
- For the quarter ending Q1 2026, Return on Equity rose 2.0% year-over-year to 0.0%; the trailing twelve-month figure through Mar 2026 stood at 0.0% (up 2.0% YoY), and the FY2025 full-year result was 0.0%, up 1.0% from the prior year.
- Return on Equity for Q1 2026 stood at 0.0%, up from 0.0% in the prior quarter.
- The five-year high for Return on Equity was 0.0% in Q4 2023, with the low at 0.03% in Q3 2022.
- Historically, Return on Equity has averaged 0.01% across 5 years, with a median of 0.0% in 2023.
- Annual changes were most pronounced in 2022 — Return on Equity fell 2 bps — and 2023, when it increased 3 bps.
- Spero Therapeutics' Return on Equity stood at 0.01% in 2022, then surged by 145 bps to 0.0% in 2023, then tumbled by 489 bps to 0.01% in 2024, then surged by 115 bps to 0.0% in 2025, then surged by 36 bps to 0.0% in 2026.
- The last three Return on Equity figures came in at 0.0% (Q1 2026), 0.0% (Q4 2025), and 0.02% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | -0.81% |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | -0.04% |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | 0.00% |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -0.01% |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | - |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 0.00% |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -0.01% |
| 10 | Spero Therapeutics | 162.39 Mn | 106.26 Mn | - | 0.00% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 0.00% |
| Dec 31, 2025 | 0.00% |
| Sep 30, 2025 | -0.02% |
| Jun 30, 2025 | -0.02% |
| Mar 31, 2025 | -0.02% |
| Dec 31, 2024 | -0.01% |
| Sep 30, 2024 | 0.00% |
| Jun 30, 2024 | 0.00% |
| Mar 31, 2024 | 0.00% |
| Dec 31, 2023 | 0.00% |
| Sep 30, 2023 | 0.00% |
| Jun 30, 2023 | 0.00% |
| Mar 31, 2023 | 0.00% |
| Dec 31, 2022 | -0.01% |
| Sep 30, 2022 | -0.03% |
| Jun 30, 2022 | -0.02% |
| Mar 31, 2022 | -0.01% |
| Dec 31, 2021 | -0.01% |
| Sep 30, 2021 | -0.01% |
| Jun 30, 2021 | -0.01% |