Growth Metrics

Spero Therapeutics (SPRO) Return on Equity (2017 - 2025)

Spero Therapeutics (SPRO) has disclosed Return on Equity for 9 consecutive years, with 1.45% as the latest value for Q3 2025.

  • For the quarter ending Q3 2025, Return on Equity fell 149.0% year-over-year to 1.45%, compared with a TTM value of 1.45% through Sep 2025, down 149.0%, and an annual FY2024 reading of 0.9%, down 115.0% over the prior year.
  • Return on Equity was 1.45% for Q3 2025 at Spero Therapeutics, up from 1.62% in the prior quarter.
  • Across five years, Return on Equity topped out at 0.3% in Q4 2023 and bottomed at 2.78% in Q3 2022.
  • Average Return on Equity over 5 years is 0.85%, with a median of 0.78% recorded in 2021.
  • The sharpest move saw Return on Equity plummeted -200bps in 2022, then skyrocketed 268bps in 2023.
  • Year by year, Return on Equity stood at 0.88% in 2021, then grew by 5bps to 0.84% in 2022, then soared by 135bps to 0.3% in 2023, then plummeted by -517bps to 1.23% in 2024, then dropped by -18bps to 1.45% in 2025.
  • Business Quant data shows Return on Equity for SPRO at 1.45% in Q3 2025, 1.62% in Q2 2025, and 1.75% in Q1 2025.