Spero Therapeutics (SPRO) Market Capitalization (2017 - 2026)
Spero Therapeutics' (SPRO) quarterly Market Capitalization came in at $128.5 million in Q2 2026, down 21.14% on a YoY basis from $162.9 million in Q2 2025, and down 5.14% quarter-over-quarter from $135.5 million in Q1 2026.
Analysis
Spero Therapeutics (SPRO) Market Capitalization (2017 - 2026) Analysis & Trends
Spero Therapeutics (SPRO) has reported Market Capitalization for 10 consecutive years, with $128.5 million the latest figure, recorded in Q2 2026.
- For the quarter ending Q2 2026, Market Capitalization fell 21.14% year-over-year to $128.5 million; the trailing twelve-month figure through Jun 2026 stood at $128.5 million (down 21.14% YoY), and the FY2025 full-year result was $131.4 million, up 133.76% from the prior year.
- Market Capitalization retreated to $128.5 million in Q2 2026 per SPRO's latest filing, from $135.5 million in the prior quarter.
- Across five years, Market Capitalization topped out at $285.0 million in Q1 2022 and bottomed at $26.0 million in Q2 2022.
- Historically, Market Capitalization has averaged $97.4 million across 5 years, with a median of $77.1 million in 2023.
- The sharpest annual moves came in 2022 and 2026: Market Capitalization plunged 93.73% in 2022, then soared 236.57% in 2026.
- Over 5 years, Market Capitalization stood at $65.0 million in 2022, then increased by 19.82% to $77.9 million in 2023, then decreased by 27.82% to $56.2 million in 2024, then soared by 133.76% to $131.4 million in 2025, then slipped by 2.24% to $128.5 million in 2026.
- According to Business Quant data, Market Capitalization over the past three periods registered $128.5 million, $135.5 million, and $131.4 million for Q2 2026, Q1 2026, and Q4 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Amgen | 211.73 Bn | 197.74 Bn | 7.24 Bn |
| 2 | Gilead Sciences | 180.92 Bn | 177.74 Bn | 6.22 Bn |
| 3 | Vertex Pharmaceuticals | 132.16 Bn | 124.30 Bn | 2.84 Bn |
| 4 | Regeneron Pharmaceuticals | 82.89 Bn | 74.90 Bn | 3.93 Bn |
| 5 | Argenx Se | 61.41 Bn | 56.23 Bn | 1.37 Bn |
| 6 | Moderna | 53.99 Bn | 48.85 Bn | 52.00 Mn |
| 7 | Alnylam Pharmaceuticals | 34.48 Bn | 31.18 Bn | 992.69 Mn |
| 8 | Biogen | 31.15 Bn | 29.86 Bn | 1.96 Bn |
| 9 | Roivant Sciences | 30.05 Bn | 30.05 Bn | 1.16 Mn |
| 10 | Spero Therapeutics | 67.82 Mn | 17.05 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 128.50 Mn |
| Mar 31, 2026 | 135.47 Mn |
| Dec 31, 2025 | 131.45 Mn |
| Sep 30, 2025 | 105.87 Mn |
| Jun 30, 2025 | 162.94 Mn |
| Mar 31, 2025 | 40.25 Mn |
| Dec 31, 2024 | 56.23 Mn |
| Sep 30, 2024 | 72.78 Mn |
| Jun 30, 2024 | 70.21 Mn |
| Mar 31, 2024 | 92.65 Mn |
| Dec 31, 2023 | 77.91 Mn |
| Sep 30, 2023 | 64.13 Mn |
| Jun 30, 2023 | 76.23 Mn |
| Mar 31, 2023 | 76.23 Mn |
| Dec 31, 2022 | 65.02 Mn |
| Sep 30, 2022 | 85.71 Mn |
| Jun 30, 2022 | 25.99 Mn |
| Mar 31, 2022 | 284.97 Mn |
| Dec 31, 2021 | 518.62 Mn |
| Sep 30, 2021 | 593.18 Mn |