Spero Therapeutics (SPRO) Market Capitalization (2017 - 2026)
Spero Therapeutics (SPRO) recorded Market Capitalization of $128.5 million in Q2 2026, down 21.1% from $162.94 million a year earlier and down 5.1% from the prior quarter.
Spero Therapeutics (SPRO) Market Capitalization (2017 - 2026) Analysis & Trends
For FY2025, Spero Therapeutics reported Market Capitalization of $131.45 million, up 133.8% from FY2024.
- Annual Market Capitalization has a five-year compound annual growth rate of -21.3% (FY2020 to FY2025).
- Across earlier years, Market Capitalization came in at $56.23 million in FY2024 (-27.8%), $77.91 million in FY2023 (+19.8%), $65.02 million in FY2022 (-87.5%) and $518.62 million in FY2021 (+19.5%).
- Quarterly Market Capitalization has ranged from $25.95 million in Q2 2022 to $593.18 million in Q3 2021 over the past five years.
- On a year-over-year basis, Market Capitalization rose in five of the last eight quarters, with growth averaging 57.0%.
- Peak year-over-year performance for Market Capitalization in the last five years was growth of 236.6% in Q1 2026, against a decline of 93.7% in Q2 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at $135.47 million (Q1 2026), $131.45 million (Q4 2025) and $105.87 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Eli Lilly | 1,163.39 Bn | 1,131.97 Bn | 19.71 Bn |
| 2 | Johnson & Johnson | 634.39 Bn | 552.91 Bn | 17.26 Bn |
| 3 | AbbVie | 502.68 Bn | 475.79 Bn | 12.70 Bn |
| 4 | Merck | 377.37 Bn | 331.74 Bn | 12.21 Bn |
| 5 | Novartis Ag | 303.41 Bn | 267.40 Bn | 11.24 Bn |
| 6 | Astrazeneca | 266.55 Bn | 240.24 Bn | 12.86 Bn |
| 7 | Amgen | 240.56 Bn | 195.96 Bn | 7.24 Bn |
| 8 | Gilead Sciences | 193.19 Bn | 167.38 Bn | 6.22 Bn |
| 9 | Pfizer | 172.14 Bn | 118.78 Bn | 10.94 Bn |
| 10 | Spero Therapeutics | 66.95 Mn | -128.83 Mn | - |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 128.50 Mn |
| Mar 31, 2026 | 135.47 Mn |
| Dec 31, 2025 | 131.45 Mn |
| Sep 30, 2025 | 105.87 Mn |
| Jun 30, 2025 | 162.94 Mn |
| Mar 31, 2025 | 40.25 Mn |
| Dec 31, 2024 | 56.23 Mn |
| Sep 30, 2024 | 72.78 Mn |
| Jun 30, 2024 | 70.21 Mn |
| Mar 31, 2024 | 92.65 Mn |
| Dec 31, 2023 | 77.91 Mn |
| Sep 30, 2023 | 64.13 Mn |
| Jun 30, 2023 | 76.23 Mn |
| Mar 31, 2023 | 76.23 Mn |
| Dec 31, 2022 | 65.02 Mn |
| Sep 30, 2022 | 85.71 Mn |
| Jun 30, 2022 | 25.95 Mn |
| Mar 31, 2022 | 284.97 Mn |
| Dec 31, 2021 | 518.62 Mn |
| Sep 30, 2021 | 593.18 Mn |
Spero Therapeutics Market Capitalization API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=market-capitalization&ticker=SPRO&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "market-capitalization", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=market-capitalization&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();