Spero Therapeutics (SPRO) Research & Development (2016 - 2026)
Spero Therapeutics' Research & Development came in at $3.43 million for Q2 2026, down 67.8% from $10.67 million a year earlier but up 18.0% from the prior quarter.
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Analysis
Spero Therapeutics (SPRO) Research & Development (2016 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Spero Therapeutics reported Research & Development of $20.53 million, down 74.3% year-over-year; for FY2025, it came in at $38.47 million, down 60.2% from FY2024.
- Research & Development carries a five-year compound annual growth rate of -10.5% (FY2020 to FY2025).
- Going back by year, Research & Development was $96.76 million in FY2024 (+88.1%), $51.44 million in FY2023 (+8.1%), $47.59 million in FY2022 (-26.2%) and $64.53 million in FY2021 (-3.7%).
- The five-year range for quarterly Research & Development is $2.91 million (Q1 2026) to $28.84 million (Q4 2024).
- Year-over-year, Research & Development has declined for six consecutive quarters, with an average decline of 29.2% over the last eight quarters.
- The fastest year-over-year change in Research & Development over five years came in Q2 2024 (growth of 149.5%), and the weakest in Q4 2025 (a decline of 80.6%).
- Business Quant data shows SPRO's Research & Development at $2.91 million (Q1 2026), $5.59 million (Q4 2025) and $8.6 million (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 3.82 Bn |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 3.65 Bn |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 2.34 Bn |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | 9.74 Bn |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 2.85 Bn |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 4.05 Bn |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 1.87 Bn |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | 1.76 Bn |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 2.81 Bn |
| 10 | Spero Therapeutics | 68.40 Mn | -127.38 Mn | - | 3.43 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 3.43 Mn |
| Mar 31, 2026 | 2.91 Mn |
| Dec 31, 2025 | 5.59 Mn |
| Sep 30, 2025 | 8.60 Mn |
| Jun 30, 2025 | 10.67 Mn |
| Mar 31, 2025 | 13.61 Mn |
| Dec 31, 2024 | 28.84 Mn |
| Sep 30, 2024 | 26.86 Mn |
| Jun 30, 2024 | 23.73 Mn |
| Mar 31, 2024 | 17.33 Mn |
| Dec 31, 2023 | 16.56 Mn |
| Sep 30, 2023 | 16.39 Mn |
| Jun 30, 2023 | 9.51 Mn |
| Mar 31, 2023 | 8.98 Mn |
| Dec 31, 2022 | 15.09 Mn |
| Sep 30, 2022 | 7.36 Mn |
| Jun 30, 2022 | 8.17 Mn |
| Mar 31, 2022 | 16.97 Mn |
| Dec 31, 2021 | 17.23 Mn |
| Sep 30, 2021 | 14.44 Mn |
API Access
Spero Therapeutics Research & Development API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=research-and-development&ticker=SPRO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "research-and-development", "ticker": "SPRO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=research-and-development&ticker=SPRO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();