Lyra Therapeutics (LYRA) Other Gross PP&E Adjustments (2019 - 2025)
Quarterly Other Gross PP&E Adjustments rose 20.31% to -$12.3 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was -$12.3 million through Dec 2025, up 20.31% year-over-year, with the annual reading at -$12.3 million for FY2025, 20.31% up from the prior year.
Lyra Therapeutics' Other Gross PP&E Adjustments history spans 7 years, with the latest figure at -$12.3 million for Q4 2025.
- Other Gross PP&E Adjustments came in at -$12.3 million for Q4 2025, down from -$12.0 million in the prior quarter.
- In the past five years, Other Gross PP&E Adjustments ranged from a high of $7.0 million in Q2 2022 to a low of -$45.6 million in Q1 2024.
- The 5-year median for Other Gross PP&E Adjustments is -$3.9 million (2023), against an average of -$6.9 million.
- Year-over-year, Other Gross PP&E Adjustments skyrocketed 4373.33% in 2021 and then tumbled 2400.05% in 2024.
- Lyra Therapeutics' Other Gross PP&E Adjustments stood at $6.2 million in 2021, then plummeted by 53.08% to $2.9 million in 2022, then tumbled by 1148.67% to -$30.4 million in 2023, then skyrocketed by 49.17% to -$15.5 million in 2024, then grew by 20.31% to -$12.3 million in 2025.
- Per Business Quant, the three most recent readings for LYRA's Other Gross PP&E Adjustments are -$12.3 million (Q4 2025), -$12.0 million (Q3 2025), and -$12.9 million (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Other Gross PP&E Adjustments (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -83,048.00 |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | -60,691.22 |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -285.20 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -892,000.00 |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | -1.69 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | - |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | - |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | -189.30 Mn |
| 10 | Lyra Therapeutics | - | - | - | -12.31 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -12.31 Mn |
| Dec 31, 2025 | -12.31 Mn |
| Sep 30, 2025 | -12.01 Mn |
| Sep 30, 2025 | -12.01 Mn |
| Jun 30, 2025 | -12.85 Mn |
| Jun 30, 2025 | -12.85 Mn |
| Mar 31, 2025 | -13.61 Mn |
| Mar 31, 2025 | -13.61 Mn |
| Dec 31, 2024 | -15.45 Mn |
| Dec 31, 2024 | -15.45 Mn |
| Sep 30, 2024 | -14.97 Mn |
| Sep 30, 2024 | -14.97 Mn |
| Jun 30, 2024 | -15.74 Mn |
| Jun 30, 2024 | -15.74 Mn |
| Mar 31, 2024 | -45.63 Mn |
| Mar 31, 2024 | -45.63 Mn |
| Dec 31, 2023 | -30.40 Mn |
| Dec 31, 2023 | -30.40 Mn |
| Sep 30, 2023 | -6.07 Mn |
| Sep 30, 2023 | -6.07 Mn |
| Jun 30, 2023 | -1.42 Mn |
| Jun 30, 2023 | -1.42 Mn |
| Mar 31, 2023 | -1.83 Mn |
| Mar 31, 2023 | -1.83 Mn |
| Dec 31, 2022 | 2.90 Mn |
| Dec 31, 2022 | 2.90 Mn |
| Sep 30, 2022 | 6.98 Mn |
| Sep 30, 2022 | 6.98 Mn |
| Jun 30, 2022 | 7.05 Mn |
| Jun 30, 2022 | 7.05 Mn |
| Mar 31, 2022 | 6.76 Mn |
| Mar 31, 2022 | 6.76 Mn |
| Dec 31, 2021 | 6.18 Mn |
| Dec 31, 2021 | 6.18 Mn |
| Sep 30, 2021 | 5.88 Mn |
| Sep 30, 2021 | 5.88 Mn |
| Jun 30, 2021 | 4.70 Mn |
| Jun 30, 2021 | 4.70 Mn |
| Mar 31, 2021 | 3.52 Mn |
| Mar 31, 2021 | 3.52 Mn |
| Dec 31, 2020 | 2.19 Mn |
| Dec 31, 2020 | 2.19 Mn |
| Sep 30, 2020 | 883,000.00 |
| Sep 30, 2020 | 883,000.00 |
| Jun 30, 2020 | 105,000.00 |
| Jun 30, 2020 | 105,000.00 |
| Mar 31, 2020 | -432,000.00 |
| Mar 31, 2020 | -432,000.00 |
| Dec 31, 2019 | -1.02 Mn |
| Dec 31, 2019 | -1.02 Mn |