Lyra Therapeutics (LYRA) Equity Average (2019 - 2025)
Quarterly Equity Average fell 146.7% to -$7.5 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was -$7.5 million through Dec 2025, down 146.7% year-over-year, with the annual reading at $438500.0 for FY2025, 99.13% down from the prior year.
Lyra Therapeutics' Equity Average history spans 7 years, with the latest figure at -$7.5 million for Q4 2025.
- Equity Average came in at -$7.5 million for Q4 2025, down from -$1.4 million in the prior quarter.
- In the past five years, Equity Average ranged from a high of $99.7 million in Q3 2022 to a low of -$7.5 million in Q4 2025.
- The 5-year median for Equity Average is $58.4 million (2021), against an average of $51.1 million.
- Year-over-year, Equity Average surged 412.95% in 2021 and then plummeted 146.7% in 2025.
- Lyra Therapeutics' Equity Average stood at $40.8 million in 2021, then surged by 113.46% to $87.0 million in 2022, then fell by 0.18% to $86.8 million in 2023, then crashed by 81.45% to $16.1 million in 2024, then tumbled by 146.7% to -$7.5 million in 2025.
- Per Business Quant, the three most recent readings for LYRA's Equity Average are -$7.5 million (Q4 2025), -$1.4 million (Q3 2025), and $2.7 million (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Equity Avg. (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | 3.76 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | 21.35 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 19.01 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 31.34 Bn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | - |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 932.28 Mn |
| 10 | Lyra Therapeutics | - | - | - | -7.52 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -7.52 Mn |
| Sep 30, 2025 | -1.36 Mn |
| Jun 30, 2025 | 2.74 Mn |
| Mar 31, 2025 | 7.73 Mn |
| Dec 31, 2024 | 16.11 Mn |
| Sep 30, 2024 | 25.80 Mn |
| Jun 30, 2024 | 54.24 Mn |
| Mar 31, 2024 | 83.46 Mn |
| Dec 31, 2023 | 86.83 Mn |
| Sep 30, 2023 | 91.41 Mn |
| Jun 30, 2023 | 82.33 Mn |
| Mar 31, 2023 | 73.42 Mn |
| Dec 31, 2022 | 86.99 Mn |
| Sep 30, 2022 | 99.74 Mn |
| Jun 30, 2022 | 64.75 Mn |
| Mar 31, 2022 | 28.79 Mn |
| Dec 31, 2021 | 40.75 Mn |
| Sep 30, 2021 | 52.34 Mn |
| Jun 30, 2021 | 62.53 Mn |
| Mar 31, 2021 | 71.02 Mn |
| Dec 31, 2020 | 77.70 Mn |
| Sep 30, 2020 | 83.87 Mn |
| Jun 30, 2020 | -19.98 Mn |
| Mar 31, 2020 | -125.06 Mn |
| Dec 31, 2019 | -121.17 Mn |
| Sep 30, 2019 | -116.93 Mn |
| Jun 30, 2019 | -112.77 Mn |