Lyra Therapeutics (LYRA) Accumulated Expenses (2019 - 2025)

Quarterly Accumulated Expenses fell 24.87% to $3.3 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was $3.3 million through Dec 2025, down 24.87% year-over-year, with the annual reading at $3.3 million for FY2025, 24.87% down from the prior year.

Lyra Therapeutics' Accumulated Expenses history spans 7 years, with the latest figure at $3.3 million for Q4 2025.

  • Accumulated Expenses came in at $3.3 million for Q4 2025, up from $3.1 million in the prior quarter.
  • In the past five years, Accumulated Expenses ranged from a high of $11.1 million in Q3 2023 to a low of $1.8 million in Q2 2021.
  • The 5-year median for Accumulated Expenses is $4.3 million (2022), against an average of $5.1 million.
  • Year-over-year, Accumulated Expenses surged 271.76% in 2022 and then crashed 77.66% in 2025.
  • Lyra Therapeutics' Accumulated Expenses stood at $2.4 million in 2021, then soared by 271.76% to $9.0 million in 2022, then increased by 3.81% to $9.4 million in 2023, then tumbled by 53.63% to $4.3 million in 2024, then decreased by 24.87% to $3.3 million in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Accumulated Expenses are $3.3 million (Q4 2025), $3.1 million (Q3 2025), and $3.5 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn -
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn -
5 Akari Therapeutics 605.66 Bn 605.66 Bn -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn
8 Evaxion A 65.12 Bn 65.10 Bn -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn
10 Lyra Therapeutics - - -

Historic Data

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DateValue
Dec 31, 2025 3.27 Mn
Sep 30, 2025 3.06 Mn
Jun 30, 2025 3.49 Mn
Mar 31, 2025 2.25 Mn
Dec 31, 2024 4.35 Mn
Sep 30, 2024 4.86 Mn
Jun 30, 2024 6.10 Mn
Mar 31, 2024 10.06 Mn
Dec 31, 2023 9.37 Mn
Sep 30, 2023 11.05 Mn
Jun 30, 2023 6.74 Mn
Mar 31, 2023 6.79 Mn
Dec 31, 2022 9.03 Mn
Sep 30, 2022 7.32 Mn
Jun 30, 2022 2.09 Mn
Mar 31, 2022 4.24 Mn
Dec 31, 2021 2.43 Mn
Sep 30, 2021 2.24 Mn
Jun 30, 2021 1.81 Mn
Mar 31, 2021 1.99 Mn
Dec 31, 2020 1.89 Mn
Sep 30, 2020 1.59 Mn
Jun 30, 2020 1.85 Mn
Mar 31, 2020 1.02 Mn
Dec 31, 2019 3.24 Mn