Lyra Therapeutics (LYRA) Operating Income (2019 - 2025)
Lyra Therapeutics' Operating Income came in at -$7.12 million for Q4 2025, compared with -$11.41 million a year earlier.
Powered by 
Analysis
Lyra Therapeutics (LYRA) Operating Income (2019 - 2025) Analysis & Trends
For FY2025, Lyra Therapeutics' Operating Income was -$31.02 million.
- Going back by year, Operating Income was -$96.35 million in FY2024, -$67.12 million in FY2023, -$56.31 million in FY2022 and -$43.62 million in FY2021.
- The five-year range for quarterly Operating Income is -$48.97 million (Q2 2024) to -$6.24 million (Q3 2025).
- Business Quant data shows LYRA's Operating Income at -$6.24 million (Q3 2025), -$8.83 million (Q2 2025) and -$8.84 million (Q1 2025) in the three quarters before Q4 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 7.14 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 6.43 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | -584.00 Mn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 4.75 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 3.16 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 3.51 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -10.39 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 4.27 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 1.25 Bn |
| 10 | Lyra Therapeutics | 354,976.41 | 354,976.41 | - | -7.12 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -7.12 Mn |
| Sep 30, 2025 | -6.24 Mn |
| Jun 30, 2025 | -8.83 Mn |
| Mar 31, 2025 | -8.84 Mn |
| Dec 31, 2024 | -11.41 Mn |
| Sep 30, 2024 | -12.44 Mn |
| Jun 30, 2024 | -48.97 Mn |
| Mar 31, 2024 | -23.52 Mn |
| Dec 31, 2023 | -16.48 Mn |
| Sep 30, 2023 | -16.83 Mn |
| Jun 30, 2023 | -16.50 Mn |
| Mar 31, 2023 | -17.31 Mn |
| Dec 31, 2022 | -15.16 Mn |
| Sep 30, 2022 | -14.83 Mn |
| Jun 30, 2022 | -14.40 Mn |
| Mar 31, 2022 | -11.93 Mn |
| Dec 31, 2021 | -13.64 Mn |
| Sep 30, 2021 | -11.08 Mn |
| Jun 30, 2021 | -11.07 Mn |
| Mar 31, 2021 | -7.83 Mn |
API Access
Lyra Therapeutics Operating Income API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-income&ticker=LYRA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-income", "ticker": "LYRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-income&ticker=LYRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();