Lyra Therapeutics (LYRA) Common Equity (2019 - 2025)

Quarterly Common Equity fell 192.44% to -$10.7 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was -$10.7 million through Dec 2025, down 192.44% year-over-year, with the annual reading at -$10.7 million for FY2025, 192.44% down from the prior year.

Lyra Therapeutics' Common Equity history spans 7 years, with the latest figure at -$10.7 million for Q4 2025.

  • Common Equity came in at -$10.7 million for Q4 2025, down from -$4.3 million in the prior quarter.
  • In the past five years, Common Equity ranged from a high of $106.2 million in Q2 2022 to a low of -$10.7 million in Q4 2025.
  • The 5-year median for Common Equity is $52.3 million (2021), against an average of $49.0 million.
  • Year-over-year, Common Equity soared 184.18% in 2023 and then plummeted 192.44% in 2025.
  • Lyra Therapeutics' Common Equity stood at $34.3 million in 2021, then skyrocketed by 135.32% to $80.8 million in 2022, then increased by 10.73% to $89.4 million in 2023, then crashed by 87.03% to $11.6 million in 2024, then tumbled by 192.44% to -$10.7 million in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Common Equity are -$10.7 million (Q4 2025), -$4.3 million (Q3 2025), and $1.6 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Common Equity (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -1.42 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - 35.63 Mn
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - 14.38 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 19.36 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 31.42 Bn
8 Evaxion A 65.12 Bn 65.10 Bn - 13.21 Mn
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 1.08 Bn
10 Lyra Therapeutics - - - -10.72 Mn

Historic Data

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DateValue
Dec 31, 2025 -10.72 Mn
Sep 30, 2025 -4.33 Mn
Jun 30, 2025 1.62 Mn
Mar 31, 2025 3.87 Mn
Dec 31, 2024 11.59 Mn
Sep 30, 2024 20.62 Mn
Jun 30, 2024 30.98 Mn
Mar 31, 2024 77.50 Mn
Dec 31, 2023 89.42 Mn
Sep 30, 2023 84.24 Mn
Jun 30, 2023 98.58 Mn
Mar 31, 2023 66.09 Mn
Dec 31, 2022 80.75 Mn
Sep 30, 2022 93.22 Mn
Jun 30, 2022 106.25 Mn
Mar 31, 2022 23.26 Mn
Dec 31, 2021 34.32 Mn
Sep 30, 2021 47.19 Mn
Jun 30, 2021 57.50 Mn
Mar 31, 2021 67.55 Mn
Dec 31, 2020 74.49 Mn
Sep 30, 2020 80.91 Mn
Jun 30, 2020 86.82 Mn
Mar 31, 2020 -126.78 Mn
Dec 31, 2019 -123.34 Mn
Sep 30, 2019 -119.01 Mn
Jun 30, 2019 -114.84 Mn
Mar 31, 2019 -110.69 Mn