Lyra Therapeutics (LYRA) Research & Development (2019 - 2025)
Lyra Therapeutics (LYRA) reported Research & Development of $4.38 million for Q4 2025, down 31.2% from $6.36 million a year earlier but up 8.2% from the prior quarter.
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Analysis
Lyra Therapeutics (LYRA) Research & Development (2019 - 2025) Analysis & Trends
For FY2025, Lyra Therapeutics posted Research & Development of $18.41 million, down 57.9% from FY2024.
- Research & Development has a five-year compound annual growth rate of 8.0% (FY2020 to FY2025).
- By year, Research & Development came in at $43.77 million in FY2024 (-8.9%), $48.03 million in FY2023 (+23.8%), $38.8 million in FY2022 (+30.7%) and $29.69 million in FY2021 (+137.1%).
- Five-year quarterly Research & Development spans a low of $4.05 million in Q3 2025 and a high of $18.24 million in Q1 2024.
- Year over year, Research & Development has now declined in each of the last six quarters, with an average decline of 28.8% over the last eight quarters.
- The high point for year-over-year Research & Development in five years was Q2 2021 (growth of 256.9%); the low point was Q1 2025 (a decline of 73.3%).
- Per Business Quant data, the three quarters before Q4 2025 came in at $4.05 million (Q3 2025), $5.11 million (Q2 2025) and $4.88 million (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 3.65 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 2.34 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 9.74 Bn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | -2.85 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | -4.05 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 1.87 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | 1.76 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 2.81 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 993.80 Mn |
| 10 | Lyra Therapeutics | 354,976.41 | 354,976.41 | - | 4.38 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 4.38 Mn |
| Sep 30, 2025 | 4.05 Mn |
| Jun 30, 2025 | 5.11 Mn |
| Mar 31, 2025 | 4.88 Mn |
| Dec 31, 2024 | 6.36 Mn |
| Sep 30, 2024 | 5.90 Mn |
| Jun 30, 2024 | 13.26 Mn |
| Mar 31, 2024 | 18.24 Mn |
| Dec 31, 2023 | 12.27 Mn |
| Sep 30, 2023 | 12.37 Mn |
| Jun 30, 2023 | 10.80 Mn |
| Mar 31, 2023 | 12.60 Mn |
| Dec 31, 2022 | 9.45 Mn |
| Sep 30, 2022 | 10.05 Mn |
| Jun 30, 2022 | 10.79 Mn |
| Mar 31, 2022 | 8.51 Mn |
| Dec 31, 2021 | 10.34 Mn |
| Sep 30, 2021 | 7.08 Mn |
| Jun 30, 2021 | 7.51 Mn |
| Mar 31, 2021 | 4.77 Mn |
API Access
Lyra Therapeutics Research & Development API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=research-and-development&ticker=LYRA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "research-and-development", "ticker": "LYRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=research-and-development&ticker=LYRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();