LYRA's three largest insider shareholders as of September 09, 2026 are Gp, Llc Nbvm (TenPercentOwner, 2.52Mn shares), Maria Palasis (Principal Executive Officer, 1.09Mn shares), Maria Palasis (Principal Executive Officer, 1.09Mn shares).
| # | Insider | Position | Direct | Indirect | Total | Share of Insiders | Last Filed |
|---|---|---|---|---|---|---|---|
| 1 | Gp, Llc Nbvm | TenPercentOwner | 0 | 2,521,745 | 2,521,745 | 52.5% | 02 Jun, 2023 |
| 2 | Maria Palasis | Principal Executive Officer | 1,094,733 | 0 | 1,094,733 | 22.8% | 03 Apr, 2026 |
| 3 | Harlan Waksal | Executive Chair | 536,966 | 0 | 536,966 | 11.2% | 20 Mar, 2024 |
| 4 | Jason Cavalier | Principal Financial Officer | 517,880 | 0 | 517,880 | 10.8% | 03 Apr, 2026 |
| 5 | Edward T Anderson | Director, TenPercentOwner | 0 | 50,435 | 50,435 | 1.1% | 02 Jun, 2023 |
| 6 | Corinne Noyes | Officer | 36,667 | 0 | 36,667 | 0.8% | 02 Feb, 2023 |
| 7 | Robert E. Richard | Svp, Technical Operations | 30,000 | 0 | 30,000 | 0.6% | 02 Feb, 2023 |
| 8 | Advisors Llc Perceptive | TenPercentOwner | 0 | 14,026 | 14,026 | 0.3% | 13 Nov, 2025 |
| 9 | C Ann Merrifield | Director | 227 | 0 | 227 | 0.0% | 13 Jun, 2022 |
Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.
| Date | Insider | Position | Transaction | Shares | Price | Value | Shares Held After | Ownership |
|---|---|---|---|---|---|---|---|---|
| 14 May, 2026 | W Bradford Smith | Director | Disposed D | 640 | $0.00 | $0 | 0 | Direct |
| 01 Apr, 2026 | Maria Palasis | Principal Executive Officer | Disposed D | 2,000 | $0.00 | $0 | 1,094,733 | Direct |
| 01 Apr, 2026 | Maria Palasis | Principal Executive Officer | Disposed D | 2,000 | $0.00 | $0 | 1,094,733 | Direct |
| 01 Apr, 2026 | Maria Palasis | Principal Executive Officer | Disposed D | 2,000 | $0.00 | $0 | 1,094,733 | Direct |
| 01 Apr, 2026 | Maria Palasis | Principal Executive Officer | Disposed D | 2,000 | $0.00 | $0 | 1,094,733 | Direct |
| 01 Apr, 2026 | Jason Cavalier | Principal Financial Officer | Disposed D | 667 | $0.00 | $0 | 517,880 | Direct |
| 06 Jan, 2026 | Maria Palasis | President Ceo | Disposed S | 1,702 | $3.36 | $5.73K | 1,096,733 | Direct |
| 06 Jan, 2026 | Maria Palasis | President Ceo | Disposed S | 1,702 | $3.36 | $5.73K | 1,096,733 | Direct |
| 06 Jan, 2026 | Jason Cavalier | Chief Financial Officer | Disposed S | 769 | $3.36 | $2.59K | 518,547 | Direct |
| 06 Jan, 2026 | Maria Palasis | President Ceo | Disposed S | 1,702 | $3.36 | $5.73K | 1,096,733 | Direct |
| 06 Jan, 2026 | Maria Palasis | President Ceo | Disposed S | 1,702 | $3.36 | $5.73K | 1,096,733 | Direct |
| 11 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 4,783 | $4.31 | $20.64K | 161,318 | Indirect |
| 11 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 4,783 | $4.31 | $20.64K | 161,318 | Indirect |
| 11 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 4,783 | $4.31 | $20.64K | 161,318 | Indirect |
| 11 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 537 | $4.31 | $2.32K | 18,122 | Indirect |
| 11 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 537 | $4.31 | $2.32K | 18,122 | Indirect |
| 11 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 537 | $4.31 | $2.32K | 18,122 | Indirect |
| 12 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 7,862 | $4.06 | $31.92K | 153,456 | Indirect |
| 12 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 7,862 | $4.06 | $31.92K | 153,456 | Indirect |
| 12 Nov, 2025 | Advisors Llc Perceptive | TenPercentOwner | Disposed S | 7,862 | $4.06 | $31.92K | 153,456 | Indirect |