Lyra Therapeutics (LYRA) Cash from Operations (2019 - 2025)
Quarterly Cash from Operations rose 46.56% to 6066000.0 in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 28859000.0 through Dec 2025, up 58.78% year-over-year, with the annual reading at 28859000.0 for FY2025, 58.78% up from the prior year.
Lyra Therapeutics' Cash from Operations history spans 7 years, with the latest figure at 6066000.0 for Q4 2025.
- Cash from Operations came in at 6066000.0 for Q4 2025, up from 7361000.0 in the prior quarter.
- In the past five years, Cash from Operations ranged from a high of 3381000.0 in Q2 2021 to a low of 22455000.0 in Q1 2024.
- The 5-year median for Cash from Operations is 11324500.0 (2021), against an average of 11568950.0.
- Year-over-year, Cash from Operations surged 145.21% in 2021 and then crashed 350.52% in 2022.
- Lyra Therapeutics' Cash from Operations stood at 11297000.0 in 2021, then dropped by 7.67% to 12164000.0 in 2022, then plummeted by 56.68% to 19058000.0 in 2023, then surged by 40.43% to 11352000.0 in 2024, then surged by 46.56% to 6066000.0 in 2025.
- Per Business Quant, the three most recent readings for LYRA's Cash from Operations are 6066000.0 (Q4 2025), 7361000.0 (Q3 2025), and 6590000.0 (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Cash from Operations (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,384,976.65 Bn | 1,384,976.64 Bn | - | -1.67 Mn |
| 2 | Alterity Therapeutics | 777,208.84 Bn | 777,208.81 Bn | - | - |
| 3 | Legend Biotech | 2,801.00 Bn | 2,800.10 Bn | 242.10 Mn | -12.20 Mn |
| 4 | Nanobiotix | 2,226.01 Bn | 2,225.95 Bn | - | - |
| 5 | Akari Therapeutics | 605.66 Bn | 605.66 Bn | - | -2.49 Mn |
| 6 | Vertex Pharmaceuticals | 110.17 Bn | 102.92 Bn | 2.59 Bn | 1.43 Bn |
| 7 | Regeneron Pharmaceuticals | 66.86 Bn | 58.11 Bn | 3.31 Bn | 1.08 Bn |
| 8 | Evaxion A | 65.12 Bn | 65.10 Bn | - | - |
| 9 | Alnylam Pharmaceuticals | 39.94 Bn | 36.94 Bn | 959.66 Mn | 70.50 Mn |
| 10 | Lyra Therapeutics | - | - | - | -6.07 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -6.07 Mn |
| Dec 31, 2025 | -6.07 Mn |
| Sep 30, 2025 | -7.36 Mn |
| Sep 30, 2025 | -7.36 Mn |
| Jun 30, 2025 | -6.59 Mn |
| Jun 30, 2025 | -6.59 Mn |
| Mar 31, 2025 | -8.84 Mn |
| Mar 31, 2025 | -8.84 Mn |
| Dec 31, 2024 | -11.35 Mn |
| Dec 31, 2024 | -11.35 Mn |
| Sep 30, 2024 | -16.22 Mn |
| Sep 30, 2024 | -16.22 Mn |
| Jun 30, 2024 | -19.98 Mn |
| Jun 30, 2024 | -19.98 Mn |
| Mar 31, 2024 | -22.46 Mn |
| Mar 31, 2024 | -22.46 Mn |
| Dec 31, 2023 | -19.06 Mn |
| Dec 31, 2023 | -19.06 Mn |
| Sep 30, 2023 | -14.11 Mn |
| Sep 30, 2023 | -14.11 Mn |
| Jun 30, 2023 | -14.28 Mn |
| Jun 30, 2023 | -14.28 Mn |
| Mar 31, 2023 | -15.85 Mn |
| Mar 31, 2023 | -15.85 Mn |
| Dec 31, 2022 | -12.16 Mn |
| Dec 31, 2022 | -12.16 Mn |
| Sep 30, 2022 | -10.85 Mn |
| Sep 30, 2022 | -10.85 Mn |
| Jun 30, 2022 | -8.47 Mn |
| Jun 30, 2022 | -8.47 Mn |
| Mar 31, 2022 | -11.91 Mn |
| Mar 31, 2022 | -11.91 Mn |
| Dec 31, 2021 | -11.30 Mn |
| Dec 31, 2021 | -11.30 Mn |
| Sep 30, 2021 | -10.31 Mn |
| Sep 30, 2021 | -10.31 Mn |
| Jun 30, 2021 | 3.38 Mn |
| Jun 30, 2021 | 3.38 Mn |
| Mar 31, 2021 | -7.59 Mn |
| Mar 31, 2021 | -7.59 Mn |
| Dec 31, 2020 | -5.87 Mn |
| Dec 31, 2020 | -5.87 Mn |
| Sep 30, 2020 | -3.78 Mn |
| Sep 30, 2020 | -3.78 Mn |
| Jun 30, 2020 | -7.48 Mn |
| Jun 30, 2020 | -7.48 Mn |
| Mar 31, 2020 | -4.02 Mn |
| Mar 31, 2020 | -4.02 Mn |
| Dec 31, 2019 | -3.92 Mn |
| Dec 31, 2019 | -3.92 Mn |
| Sep 30, 2019 | -3.83 Mn |
| Sep 30, 2019 | -3.83 Mn |
| Jun 30, 2019 | -3.00 Mn |
| Jun 30, 2019 | -3.00 Mn |
| Mar 31, 2019 | -3.01 Mn |
| Mar 31, 2019 | -3.01 Mn |