Lyra Therapeutics LYRA
LYRA
$0.00 -0.04 (-100.00%)
At close: Aug 19, 2026 · 4:00 PM EDT

Lyra Therapeutics (LYRA) Cash from Operations (2019 - 2025)

Lyra Therapeutics (LYRA) recorded quarterly Cash from Operations of 6066000.0 in Q4 2025, up 17.59% on a QoQ basis from 7361000.0 in Q3 2025, and up 46.56% YoY from 4138792.64 in Q4 2024.

Lyra Therapeutics (LYRA) Cash from Operations (2019 - 2025) Analysis & Trends

Lyra Therapeutics (LYRA) has reported Cash from Operations for 7 consecutive years, with 6066000.0 the latest figure, recorded in Q4 2025.

  • Cash from Operations for Q4 2025 came in at 6066000.0, up 46.56% year-over-year; the trailing twelve-month figure through Dec 2025 was 28859000.0 (up 58.78% YoY), and the FY2025 annual result was 28859000.0, up 58.78% from the prior year.
  • Cash from Operations for Q4 2025 stood at 6066000.0, up from 7361000.0 in the prior quarter.
  • The five-year high for Cash from Operations was 3381000.0 in Q2 2021, with the low at 22455000.0 in Q1 2024.
  • A 5-year average of 11568950.0 and a median of 11324500.0 in 2021 frame the typical range for Cash from Operations.
  • Across the five-year window, Cash from Operations surged 145.21% in 2021 and slumped 350.52% in 2022, its largest moves.
  • Lyra Therapeutics' Cash from Operations stood at 11297000.0 in 2021, then fell by 7.67% to 12164000.0 in 2022, then plunged by 56.68% to 19058000.0 in 2023, then jumped by 40.43% to 11352000.0 in 2024, then jumped by 46.56% to 6066000.0 in 2025.
  • The last three Cash from Operations figures came in at 6066000.0 (Q4 2025), 7361000.0 (Q3 2025), and 6590000.0 (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Ops. (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.13 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 813.00 Mn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn -
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -526.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 462.82 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 326.72 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 360.27 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -88.83 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 728.46 Mn
10 Lyra Therapeutics 70,995.28 70,995.28 - -6.07 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -6.07 Mn
Dec 31, 2025 -6.07 Mn
Sep 30, 2025 -7.36 Mn
Sep 30, 2025 -7.36 Mn
Jun 30, 2025 -6.59 Mn
Jun 30, 2025 -6.59 Mn
Mar 31, 2025 -8.84 Mn
Mar 31, 2025 -8.84 Mn
Dec 31, 2024 -11.35 Mn
Dec 31, 2024 -11.35 Mn
Sep 30, 2024 -16.22 Mn
Sep 30, 2024 -16.22 Mn
Jun 30, 2024 -19.98 Mn
Jun 30, 2024 -19.98 Mn
Mar 31, 2024 -22.46 Mn
Mar 31, 2024 -22.46 Mn
Dec 31, 2023 -19.06 Mn
Dec 31, 2023 -19.06 Mn
Sep 30, 2023 -14.11 Mn
Sep 30, 2023 -14.11 Mn