Lyra Therapeutics (LYRA) EPS (Basic) (2019 - 2025)
Lyra Therapeutics (LYRA) recorded quarterly EPS (Basic) of -$0.56 in Q4 2025, up 83.46% on a QoQ basis from -$3.38 in Q3 2025, and down 108.41% YoY from $6.66 in Q4 2024.
Lyra Therapeutics (LYRA) EPS (Basic) (2019 - 2025) Analysis & Trends
Lyra Therapeutics (LYRA) has reported EPS (Basic) for 7 consecutive years, with -$0.56 the latest figure, recorded in Q4 2025.
- EPS (Basic) for Q4 2025 came in at -$0.56, down 108.41% year-over-year; the trailing twelve-month figure through Dec 2025 was -$14.7 (up 74.05% YoY), and the FY2025 annual result was -$14.7, up 74.05% from the prior year.
- EPS (Basic) for Q4 2025 stood at -$0.56, up from -$3.38 in the prior quarter.
- The five-year high for EPS (Basic) was $6.66 in Q4 2024, with the low at -$56.9 in Q3 2021.
- A 5-year average of -$23.36 and a median of -$18.96 in 2022 frame the typical range for EPS (Basic).
- Across the five-year window, EPS (Basic) jumped 143.78% in 2024 and slumped 108.41% in 2025, its largest moves.
- Lyra Therapeutics' EPS (Basic) stood at -$52.71 in 2021, then jumped by 55.38% to -$23.52 in 2022, then surged by 35.3% to -$15.22 in 2023, then jumped by 143.78% to $6.66 in 2024, then tumbled by 108.41% to -$0.56 in 2025.
- The last three EPS (Basic) figures came in at -$0.56 (Q4 2025), -$3.38 (Q3 2025), and -$5.51 (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EPS (Basic) (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.71 Bn | 131.86 Bn | 2.84 Bn | 4.34 |
| 2 | Regeneron Pharmaceuticals | 86.87 Bn | 78.87 Bn | 3.93 Bn | 12.62 |
| 3 | Argenx Se | 65.40 Bn | 60.22 Bn | 1.37 Bn | 7.59 |
| 4 | Moderna | 59.36 Bn | 54.22 Bn | 52.00 Mn | -1.96 |
| 5 | BeOne Medicines | 42.12 Bn | 37.02 Bn | 1.53 Bn | 2.12 |
| 6 | Alnylam Pharmaceuticals | 31.91 Bn | 28.60 Bn | 992.69 Mn | 1.23 |
| 7 | BioNTech SE | 28.17 Bn | 9.78 Bn | 668.28 Mn | -0.72 |
| 8 | Insmed | 27.58 Bn | 26.42 Bn | 358.27 Mn | -0.06 |
| 9 | Royalty Pharma | 27.33 Bn | 26.49 Bn | - | 0.18 |
| 10 | Lyra Therapeutics | 70,995.28 | 70,995.28 | - | -0.56 |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -0.56 |
| Sep 30, 2025 | -3.38 |
| Jun 30, 2025 | -5.51 |
| Mar 31, 2025 | -6.50 |
| Dec 31, 2024 | 6.66 |
| Sep 30, 2024 | -9.07 |
| Jun 30, 2024 | -36.76 |
| Mar 31, 2024 | -17.54 |
| Dec 31, 2023 | -15.22 |
| Sep 30, 2023 | -13.74 |
| Jun 30, 2023 | -17.88 |
| Mar 31, 2023 | -22.07 |
| Dec 31, 2022 | -23.52 |
| Sep 30, 2022 | -20.05 |
| Jun 30, 2022 | -21.16 |
| Mar 31, 2022 | -45.78 |
| Dec 31, 2021 | -52.71 |
| Sep 30, 2021 | -56.90 |
| Jun 30, 2021 | -53.95 |
| Mar 31, 2021 | -51.53 |