Lyra Therapeutics (LYRA) Cash from Investing Activities (2019 - 2025)

Quarterly Cash from Investing Activities fell 100.34% to -$96000.0 in Q4 2025 from the year-ago period, while the trailing twelve-month figure was $36.2 million through Dec 2025, down 54.95% year-over-year, with the annual reading at -$98000.0 for FY2025, 100.12% down from the prior year.

Lyra Therapeutics' Cash from Investing Activities history spans 7 years, with the latest figure at -$96000.0 for Q4 2025.

  • Cash from Investing Activities came in at -$96000.0 for Q4 2025, down from $28.1 million in the prior quarter.
  • In the past five years, Cash from Investing Activities ranged from a high of $36.2 million in Q2 2024 to a low of -$64.9 million in Q4 2022.
  • The 5-year median for Cash from Investing Activities is -$96000.0 (2025), against an average of -$45058.8.
  • Year-over-year, Cash from Investing Activities crashed 51551.72% in 2023 and then surged 6548.48% in 2024.
  • Lyra Therapeutics' Cash from Investing Activities stood at -$1.1 million in 2021, then tumbled by 5889.84% to -$64.9 million in 2022, then soared by 96.36% to -$2.4 million in 2023, then surged by 1292.5% to $28.1 million in 2024, then crashed by 100.34% to -$96000.0 in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Cash from Investing Activities are -$96000.0 (Q4 2025), $28.1 million (Q4 2024), and $8.1 million (Q3 2024).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -2.89 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 638.50 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn -431.90 Mn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -428.90 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn -25.54 Mn
10 Lyra Therapeutics - - - -96,000.00

Historic Data

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DateValue
Dec 31, 2025 -96,000.00
Dec 31, 2025 -96,000.00
Dec 31, 2024 28.13 Mn
Dec 31, 2024 28.13 Mn
Sep 30, 2024 8.14 Mn
Sep 30, 2024 8.14 Mn
Jun 30, 2024 36.18 Mn
Jun 30, 2024 36.18 Mn
Mar 31, 2024 7.86 Mn
Mar 31, 2024 7.86 Mn
Dec 31, 2023 -2.36 Mn
Dec 31, 2023 -2.36 Mn
Sep 30, 2023 -14.98 Mn
Sep 30, 2023 -14.98 Mn
Jun 30, 2023 -561,000.00
Jun 30, 2023 -561,000.00
Mar 31, 2023 5.32 Mn
Mar 31, 2023 5.32 Mn
Dec 31, 2022 -64.87 Mn
Dec 31, 2022 -64.87 Mn
Sep 30, 2022 -29,000.00
Sep 30, 2022 -29,000.00
Jun 30, 2022 -14,000.00
Jun 30, 2022 -14,000.00
Mar 31, 2022 -93,000.00
Mar 31, 2022 -93,000.00
Dec 31, 2021 -1.08 Mn
Dec 31, 2021 -1.08 Mn
Sep 30, 2021 -517,000.00
Sep 30, 2021 -517,000.00
Jun 30, 2021 -625,000.00
Jun 30, 2021 -625,000.00
Mar 31, 2021 -1.16 Mn
Mar 31, 2021 -1.16 Mn
Dec 31, 2020 -1.10 Mn
Dec 31, 2020 -1.10 Mn
Sep 30, 2020 -589,000.00
Sep 30, 2020 -589,000.00
Jun 30, 2020 -77,000.00
Jun 30, 2020 -77,000.00
Mar 31, 2020 -8,000.00
Mar 31, 2020 -8,000.00
Dec 31, 2019 -80,000.00
Dec 31, 2019 -80,000.00
Sep 30, 2019 -10,000.00
Sep 30, 2019 -10,000.00
Jun 30, 2019 -69,000.00
Jun 30, 2019 -69,000.00
Mar 31, 2019 -52,000.00
Mar 31, 2019 -52,000.00