Lyra Therapeutics (LYRA) Accumulated Depreciation & Amortization (2019 - 2025)

Quarterly Accumulated Depreciation & Amortization rose 10.17% to $4.5 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was $4.5 million through Dec 2025, up 10.17% year-over-year, with the annual reading at $4.5 million for FY2025, 10.17% up from the prior year.

Lyra Therapeutics' Accumulated Depreciation & Amortization history spans 7 years, with the latest figure at $4.5 million for Q4 2025.

  • Accumulated Depreciation & Amortization came in at $4.5 million for Q4 2025, up from $4.4 million in the prior quarter.
  • In the past five years, Accumulated Depreciation & Amortization ranged from a high of $4.7 million in Q3 2022 to a low of $1.9 million in Q4 2023.
  • The 5-year median for Accumulated Depreciation & Amortization is $4.1 million (2022), against an average of $3.9 million.
  • Year-over-year, Accumulated Depreciation & Amortization tumbled 53.98% in 2023 and then skyrocketed 114.94% in 2024.
  • Lyra Therapeutics' Accumulated Depreciation & Amortization stood at $3.9 million in 2021, then rose by 7.61% to $4.2 million in 2022, then crashed by 53.98% to $1.9 million in 2023, then surged by 114.94% to $4.1 million in 2024, then rose by 10.17% to $4.5 million in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Accumulated Depreciation & Amortization are $4.5 million (Q4 2025), $4.4 million (Q3 2025), and $4.3 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn -
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn -
5 Akari Therapeutics 605.66 Bn 605.66 Bn -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn
8 Evaxion A 65.12 Bn 65.10 Bn -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn
10 Lyra Therapeutics - - -

Historic Data

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DateValue
Dec 31, 2025 4.55 Mn
Dec 31, 2025 4.55 Mn
Sep 30, 2025 4.45 Mn
Sep 30, 2025 4.45 Mn
Jun 30, 2025 4.35 Mn
Jun 30, 2025 4.35 Mn
Mar 31, 2025 4.26 Mn
Mar 31, 2025 4.26 Mn
Dec 31, 2024 4.13 Mn
Dec 31, 2024 4.13 Mn
Sep 30, 2024 4.12 Mn
Sep 30, 2024 4.12 Mn
Jun 30, 2024 4.08 Mn
Jun 30, 2024 4.08 Mn
Dec 31, 2023 1.92 Mn
Dec 31, 2023 1.92 Mn
Dec 31, 2022 4.17 Mn
Dec 31, 2022 4.17 Mn
Sep 30, 2022 4.72 Mn
Sep 30, 2022 4.72 Mn
Jun 30, 2022 4.45 Mn
Jun 30, 2022 4.45 Mn
Mar 31, 2022 4.16 Mn
Mar 31, 2022 4.16 Mn
Dec 31, 2021 3.88 Mn
Dec 31, 2021 3.88 Mn
Sep 30, 2021 3.60 Mn
Sep 30, 2021 3.60 Mn
Jun 30, 2021 3.25 Mn
Jun 30, 2021 3.25 Mn
Mar 31, 2021 2.95 Mn
Mar 31, 2021 2.95 Mn
Dec 31, 2020 2.88 Mn
Dec 31, 2020 2.88 Mn
Sep 30, 2020 2.84 Mn
Sep 30, 2020 2.84 Mn
Jun 30, 2020 2.85 Mn
Jun 30, 2020 2.85 Mn
Mar 31, 2020 2.84 Mn
Mar 31, 2020 2.84 Mn
Dec 31, 2019 2.83 Mn
Dec 31, 2019 2.83 Mn