Lyra Therapeutics (LYRA) Leases (2019 - 2025)

Quarterly Leases fell 15.72% to $16.8 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was $16.8 million through Dec 2025, down 15.72% year-over-year, with the annual reading at $16.8 million for FY2025, 15.72% down from the prior year.

Lyra Therapeutics' Leases history spans 7 years, with the latest figure at $16.8 million for Q4 2025.

  • Leases came in at $16.8 million for Q4 2025, down from $17.6 million in the prior quarter.
  • In the past five years, Leases ranged from a high of $45.6 million in Q1 2024 to a low of $608000.0 in Q3 2022.
  • The 5-year median for Leases is $4.1 million (2022), against an average of $11.7 million.
  • Year-over-year, Leases plummeted 61.9% in 2022 and then skyrocketed 2400.05% in 2024.
  • Lyra Therapeutics' Leases stood at $1.4 million in 2021, then skyrocketed by 64.06% to $2.2 million in 2022, then surged by 1394.96% to $33.2 million in 2023, then tumbled by 40.05% to $19.9 million in 2024, then fell by 15.72% to $16.8 million in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Leases are $16.8 million (Q4 2025), $17.6 million (Q3 2025), and $18.4 million (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Leases (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 83,048.00
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - 61,822.50
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 285.20 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 1.69 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 189.30 Mn
10 Lyra Therapeutics - - - 16.79 Mn

Historic Data

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DateValue
Dec 31, 2025 16.79 Mn
Sep 30, 2025 17.58 Mn
Jun 30, 2025 18.36 Mn
Mar 31, 2025 19.14 Mn
Dec 31, 2024 19.92 Mn
Sep 30, 2024 20.71 Mn
Jun 30, 2024 21.49 Mn
Mar 31, 2024 45.63 Mn
Dec 31, 2023 33.23 Mn
Sep 30, 2023 6.07 Mn
Jun 30, 2023 1.42 Mn
Mar 31, 2023 1.83 Mn
Dec 31, 2022 2.22 Mn
Sep 30, 2022 608,000.00
Jun 30, 2022 860,000.00
Mar 31, 2022 1.11 Mn
Dec 31, 2021 1.36 Mn
Sep 30, 2021 1.60 Mn
Jun 30, 2021 1.83 Mn
Mar 31, 2021 2.07 Mn
Dec 31, 2020 2.30 Mn
Sep 30, 2020 2.53 Mn
Jun 30, 2020 2.76 Mn
Mar 31, 2020 2.96 Mn
Dec 31, 2019 3.18 Mn