Lyra Therapeutics (LYRA) EBITDA (2019 - 2025)
Lyra Therapeutics (LYRA) recorded EBITDA of -$7.06 million in Q4 2025, compared with -$11.23 million a year earlier.
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Analysis
Lyra Therapeutics (LYRA) EBITDA (2019 - 2025) Analysis & Trends
For FY2025, Lyra Therapeutics reported EBITDA of -$30.56 million.
- Across earlier years, EBITDA came in at -$95.85 million in FY2024, -$66.82 million in FY2023, -$55.21 million in FY2022 and -$42.61 million in FY2021.
- Quarterly EBITDA has ranged from -$48.77 million in Q2 2024 to -$6.14 million in Q3 2025 over the past five years.
- Per Business Quant, the preceding three quarters came in at -$6.14 million (Q3 2025), -$8.63 million (Q2 2025) and -$8.71 million (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 9.10 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 8.33 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 999.00 Mn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 5.09 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 4.63 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | -9.70 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 5.89 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 1.30 Bn |
| 10 | Lyra Therapeutics | 354,976.41 | 354,976.41 | - | -7.06 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -7.06 Mn |
| Sep 30, 2025 | -6.14 Mn |
| Jun 30, 2025 | -8.63 Mn |
| Mar 31, 2025 | -8.71 Mn |
| Dec 31, 2024 | -11.23 Mn |
| Sep 30, 2024 | -12.42 Mn |
| Jun 30, 2024 | -48.77 Mn |
| Mar 31, 2024 | -23.39 Mn |
| Dec 31, 2023 | -16.37 Mn |
| Sep 30, 2023 | -16.90 Mn |
| Jun 30, 2023 | -16.53 Mn |
| Mar 31, 2023 | -17.03 Mn |
| Dec 31, 2022 | -14.90 Mn |
| Sep 30, 2022 | -14.53 Mn |
| Jun 30, 2022 | -14.10 Mn |
| Mar 31, 2022 | -11.65 Mn |
| Dec 31, 2021 | -13.36 Mn |
| Sep 30, 2021 | -10.68 Mn |
| Jun 30, 2021 | -10.77 Mn |
| Mar 31, 2021 | -7.76 Mn |
API Access
Lyra Therapeutics EBITDA API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda&ticker=LYRA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda", "ticker": "LYRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda&ticker=LYRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();