Lyra Therapeutics (LYRA) EBT (2019 - 2025)
Lyra Therapeutics (LYRA) posted EBT of -$6.9 million for Q4 2025, down 16.18% on a QoQ basis from -$6.0 million in Q3 2025, and up 36.67% year-over-year from -$5.1 million in Q4 2024.
Analysis
Lyra Therapeutics (LYRA) EBT (2019 - 2025) Analysis & Trends
Lyra Therapeutics has reported EBT for 7 years, with the latest figure at -$6.9 million in Q4 2025.
- On a quarterly basis, EBT rose 36.67% year-over-year to -$6.9 million in Q4 2025; TTM through Dec 2025 was -$28.9 million, a 69.05% increase from a year earlier, with the FY2025 full-year figure at -$28.9 million, up 69.05% from the prior year.
- EBT was -$6.9 million for Q4 2025 at Lyra Therapeutics, down from -$6.0 million in the prior quarter.
- The five-year high for EBT was -$6.0 million in Q3 2025, with the low at -$48.1 million in Q2 2024.
- Average EBT over 5 years is -$14.2 million, with a median of -$12.8 million recorded in 2021.
- The sharpest annual moves came in 2024 and 2025: EBT plunged 208.34% in 2024, then soared 84.55% in 2025.
- Over 5 years, EBT stood at -$13.6 million in 2021, then decreased by 4.44% to -$14.2 million in 2022, then decreased by 6.45% to -$15.1 million in 2023, then rose by 27.52% to -$11.0 million in 2024, then surged by 36.67% to -$6.9 million in 2025.
- The last three EBT figures came in at -$6.9 million (Q4 2025), -$6.0 million (Q3 2025), and -$7.4 million (Q2 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 206.59 Bn | 192.60 Bn | 7.24 Bn | 2.77 Bn |
| 2 | Gilead Sciences | 180.21 Bn | 177.03 Bn | 6.22 Bn | -10.25 Bn |
| 3 | Vertex Pharmaceuticals | 131.41 Bn | 123.56 Bn | 2.84 Bn | 1.39 Bn |
| 4 | Regeneron Pharmaceuticals | 81.94 Bn | 73.94 Bn | 3.93 Bn | 1.53 Bn |
| 5 | Argenx Se | 60.60 Bn | 55.41 Bn | 1.37 Bn | 542.00 Mn |
| 6 | Moderna | 53.61 Bn | 48.47 Bn | 52.00 Mn | -767.00 Mn |
| 7 | Alnylam Pharmaceuticals | 33.49 Bn | 30.18 Bn | 992.69 Mn | 177.81 Mn |
| 8 | Biogen | 31.83 Bn | 30.54 Bn | 1.96 Bn | 132.40 Mn |
| 9 | Roivant Sciences | 29.14 Bn | 29.14 Bn | 1.16 Mn | -294.56 Mn |
| 10 | Lyra Therapeutics | 354,976.41 | 354,976.41 | - | -6.95 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | -6.95 Mn |
| Sep 30, 2025 | -5.98 Mn |
| Jun 30, 2025 | -7.44 Mn |
| Mar 31, 2025 | -8.54 Mn |
| Dec 31, 2024 | -10.97 Mn |
| Sep 30, 2024 | -11.87 Mn |
| Jun 30, 2024 | -48.12 Mn |
| Mar 31, 2024 | -22.44 Mn |
| Dec 31, 2023 | -15.14 Mn |
| Sep 30, 2023 | -15.64 Mn |
| Jun 30, 2023 | -15.61 Mn |
| Mar 31, 2023 | -16.24 Mn |
| Dec 31, 2022 | -14.22 Mn |
| Sep 30, 2022 | -14.77 Mn |
| Jun 30, 2022 | -14.37 Mn |
| Mar 31, 2022 | -11.91 Mn |
| Dec 31, 2021 | -13.62 Mn |
| Sep 30, 2021 | -11.06 Mn |
| Jun 30, 2021 | -11.04 Mn |
| Mar 31, 2021 | -7.80 Mn |