Lyra Therapeutics LYRA
LYRA
$0.19 +0.00 (+0.00%)
At close: Sep 8, 2026 · 4:00 PM EDT

Lyra Therapeutics (LYRA) EBT (2019 - 2025)

Lyra Therapeutics (LYRA) posted EBT of -$6.9 million for Q4 2025, down 16.18% on a QoQ basis from -$6.0 million in Q3 2025, and up 36.67% year-over-year from -$5.1 million in Q4 2024.

Analysis

Lyra Therapeutics (LYRA) EBT (2019 - 2025) Analysis & Trends

Lyra Therapeutics has reported EBT for 7 years, with the latest figure at -$6.9 million in Q4 2025.

  • On a quarterly basis, EBT rose 36.67% year-over-year to -$6.9 million in Q4 2025; TTM through Dec 2025 was -$28.9 million, a 69.05% increase from a year earlier, with the FY2025 full-year figure at -$28.9 million, up 69.05% from the prior year.
  • EBT was -$6.9 million for Q4 2025 at Lyra Therapeutics, down from -$6.0 million in the prior quarter.
  • The five-year high for EBT was -$6.0 million in Q3 2025, with the low at -$48.1 million in Q2 2024.
  • Average EBT over 5 years is -$14.2 million, with a median of -$12.8 million recorded in 2021.
  • The sharpest annual moves came in 2024 and 2025: EBT plunged 208.34% in 2024, then soared 84.55% in 2025.
  • Over 5 years, EBT stood at -$13.6 million in 2021, then decreased by 4.44% to -$14.2 million in 2022, then decreased by 6.45% to -$15.1 million in 2023, then rose by 27.52% to -$11.0 million in 2024, then surged by 36.67% to -$6.9 million in 2025.
  • The last three EBT figures came in at -$6.9 million (Q4 2025), -$6.0 million (Q3 2025), and -$7.4 million (Q2 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Amgen 206.59 Bn 192.60 Bn 7.24 Bn 2.77 Bn
2 Gilead Sciences 180.21 Bn 177.03 Bn 6.22 Bn -10.25 Bn
3 Vertex Pharmaceuticals 131.41 Bn 123.56 Bn 2.84 Bn 1.39 Bn
4 Regeneron Pharmaceuticals 81.94 Bn 73.94 Bn 3.93 Bn 1.53 Bn
5 Argenx Se 60.60 Bn 55.41 Bn 1.37 Bn 542.00 Mn
6 Moderna 53.61 Bn 48.47 Bn 52.00 Mn -767.00 Mn
7 Alnylam Pharmaceuticals 33.49 Bn 30.18 Bn 992.69 Mn 177.81 Mn
8 Biogen 31.83 Bn 30.54 Bn 1.96 Bn 132.40 Mn
9 Roivant Sciences 29.14 Bn 29.14 Bn 1.16 Mn -294.56 Mn
10 Lyra Therapeutics 354,976.41 354,976.41 - -6.95 Mn
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 -6.95 Mn
Sep 30, 2025 -5.98 Mn
Jun 30, 2025 -7.44 Mn
Mar 31, 2025 -8.54 Mn
Dec 31, 2024 -10.97 Mn
Sep 30, 2024 -11.87 Mn
Jun 30, 2024 -48.12 Mn
Mar 31, 2024 -22.44 Mn
Dec 31, 2023 -15.14 Mn
Sep 30, 2023 -15.64 Mn
Jun 30, 2023 -15.61 Mn
Mar 31, 2023 -16.24 Mn
Dec 31, 2022 -14.22 Mn
Sep 30, 2022 -14.77 Mn
Jun 30, 2022 -14.37 Mn
Mar 31, 2022 -11.91 Mn
Dec 31, 2021 -13.62 Mn
Sep 30, 2021 -11.06 Mn
Jun 30, 2021 -11.04 Mn
Mar 31, 2021 -7.80 Mn