Lyra Therapeutics LYRA
LYRA
$0.00 -0.04 (-100.00%)
At close: Aug 19, 2026 · 4:00 PM EDT

Lyra Therapeutics (LYRA) Profit After Tax (2019 - 2025)

Lyra Therapeutics (LYRA) recorded quarterly Profit After Tax of -$7.0 million in Q4 2025, down 16.16% on a QoQ basis from -$6.0 million in Q3 2025, and up 36.61% YoY from -$5.1 million in Q4 2024.

Lyra Therapeutics (LYRA) Profit After Tax (2019 - 2025) Analysis & Trends

Lyra Therapeutics (LYRA) has reported Profit After Tax for 7 consecutive years, with -$7.0 million the latest figure, recorded in Q4 2025.

  • Profit After Tax for Q4 2025 came in at -$7.0 million, up 36.61% year-over-year; the trailing twelve-month figure through Dec 2025 was -$28.9 million (up 69.04% YoY), and the FY2025 annual result was -$28.9 million, up 69.05% from the prior year.
  • Profit After Tax for Q4 2025 stood at -$7.0 million, down from -$6.0 million in the prior quarter.
  • The five-year high for Profit After Tax was -$6.0 million in Q3 2025, with the low at -$48.1 million in Q2 2024.
  • A 5-year average of -$14.2 million and a median of -$12.8 million in 2021 frame the typical range for Profit After Tax.
  • Across the five-year window, Profit After Tax slumped 208.18% in 2024 and jumped 84.55% in 2025, its largest moves.
  • Lyra Therapeutics' Profit After Tax stood at -$13.6 million in 2021, then retreated by 4.5% to -$14.2 million in 2022, then retreated by 6.54% to -$15.2 million in 2023, then rose by 27.65% to -$11.0 million in 2024, then soared by 36.61% to -$7.0 million in 2025.
  • The last three Profit After Tax figures came in at -$7.0 million (Q4 2025), -$6.0 million (Q3 2025), and -$7.4 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 472.00 Mn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn -782.00 Mn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 237.01 Mn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 164.49 Mn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn -355.03 Mn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn -16.62 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 81.49 Mn
10 Lyra Therapeutics 70,995.28 70,995.28 - -6.95 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -6.95 Mn
Sep 30, 2025 -5.98 Mn
Jun 30, 2025 -7.44 Mn
Mar 31, 2025 -8.55 Mn
Dec 31, 2024 -10.97 Mn
Sep 30, 2024 -11.85 Mn
Jun 30, 2024 -48.13 Mn
Mar 31, 2024 -22.45 Mn
Dec 31, 2023 -15.16 Mn
Sep 30, 2023 -15.65 Mn
Jun 30, 2023 -15.62 Mn
Mar 31, 2023 -16.26 Mn
Dec 31, 2022 -14.23 Mn
Sep 30, 2022 -14.77 Mn
Jun 30, 2022 -14.37 Mn
Mar 31, 2022 -11.91 Mn
Dec 31, 2021 -13.61 Mn
Sep 30, 2021 -11.06 Mn
Jun 30, 2021 -11.04 Mn
Mar 31, 2021 -7.80 Mn