Lyra Therapeutics (LYRA) Enterprise Value (2021 - 2025)

Lyra Therapeutics has reported Enterprise Value over the past 5 years, most recently at -$15.9 million for Q4 2025.

  • Quarterly results put Enterprise Value at -$15.9 million for Q4 2025, up 60.83% from a year ago — trailing twelve months through Dec 2025 was -$15.9 million (up 60.83% YoY), and the annual figure for FY2025 was -$15.9 million, up 60.83%.
  • Enterprise Value for Q4 2025 was -$15.9 million at Lyra Therapeutics, up from -$22.1 million in the prior quarter.
  • Over the last five years, Enterprise Value for LYRA hit a ceiling of -$15.9 million in Q4 2025 and a floor of -$122.4 million in Q2 2022.
  • Median Enterprise Value over the past 5 years was -$69.3 million (2021), compared with a mean of -$66.9 million.
  • Biggest five-year swings in Enterprise Value: tumbled 146.78% in 2023 and later soared 64.38% in 2025.
  • Lyra Therapeutics' Enterprise Value stood at -$46.1 million in 2021, then tumbled by 115.48% to -$99.3 million in 2022, then decreased by 4.89% to -$104.1 million in 2023, then surged by 61.04% to -$40.6 million in 2024, then skyrocketed by 60.83% to -$15.9 million in 2025.
  • The last three reported values for Enterprise Value were -$15.9 million (Q4 2025), -$22.1 million (Q3 2025), and -$29.8 million (Q2 2025) per Business Quant data.