Lyra Therapeutics (LYRA) Equity Ratio (2019 - 2025)

Quarterly Equity Ratio fell 269.84% to 0.3 in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 0.3 through Dec 2025, down 269.84% year-over-year, with the annual reading at 0.3 for FY2025, 269.84% down from the prior year.

Lyra Therapeutics' Equity Ratio history spans 7 years, with the latest figure at 0.3 for Q4 2025.

  • Equity Ratio came in at 0.3 for Q4 2025, down from 0.1 in the prior quarter.
  • In the past five years, Equity Ratio ranged from a high of 0.93 in Q1 2021 to a low of 0.3 in Q4 2025.
  • The 5-year median for Equity Ratio is 0.63 (2021), against an average of 0.48.
  • Year-over-year, Equity Ratio skyrocketed 129.79% in 2021 and then tumbled 269.84% in 2025.
  • Lyra Therapeutics' Equity Ratio stood at 0.63 in 2021, then increased by 17.41% to 0.73 in 2022, then dropped by 14.61% to 0.63 in 2023, then tumbled by 72.13% to 0.17 in 2024, then crashed by 269.84% to 0.3 in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Equity Ratio are 0.3 (Q4 2025), 0.1 (Q3 2025), and 0.03 (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Equity Ratio (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 0.04
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn -
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - 0.42
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 0.73
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 0.77
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 0.21
10 Lyra Therapeutics - - - -0.30

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -0.30
Sep 30, 2025 -0.10
Jun 30, 2025 0.03
Mar 31, 2025 0.07
Dec 31, 2024 0.17
Sep 30, 2024 0.26
Jun 30, 2024 0.33
Mar 31, 2024 0.55
Dec 31, 2023 0.63
Sep 30, 2023 0.70
Jun 30, 2023 0.78
Mar 31, 2023 0.70
Dec 31, 2022 0.73
Sep 30, 2022 0.78
Jun 30, 2022 0.82
Mar 31, 2022 0.49
Dec 31, 2021 0.63
Sep 30, 2021 0.70
Jun 30, 2021 0.75
Mar 31, 2021 0.93
Dec 31, 2020 0.92
Sep 30, 2020 0.93
Jun 30, 2020 0.94
Mar 31, 2020 -3.11
Dec 31, 2019 -8.24