Lyra Therapeutics (LYRA) Revenue (2021 - 2025)

Quarterly Revenue fell 96.65% to $7000.0 in Q4 2025 from the year-ago period, while the trailing twelve-month figure was $398000.0 through Dec 2025, down 74.05% year-over-year, with the annual reading at $398000.0 for FY2025, 74.05% down from the prior year.

Lyra Therapeutics' Revenue history spans 5 years, with the latest figure at $7000.0 for Q4 2025.

  • Revenue came in at $7000.0 for Q4 2025, down from $25000.0 in the prior quarter.
  • In the past five years, Revenue ranged from a high of $598000.0 in Q2 2024 to a low of $7000.0 in Q4 2025.
  • The 5-year median for Revenue is $240000.0 (2021), against an average of $285444.4.
  • Year-over-year, Revenue surged 2464.29% in 2022 and then plummeted 96.65% in 2025.
  • Lyra Therapeutics' Revenue stood at $271000.0 in 2021, then tumbled by 95.94% to $11000.0 in 2022, then surged by 1227.27% to $146000.0 in 2023, then surged by 43.15% to $209000.0 in 2024, then tumbled by 96.65% to $7000.0 in 2025.
  • Per Business Quant, the three most recent readings for LYRA's Revenue are $7000.0 (Q4 2025), $25000.0 (Q3 2025), and $183000.0 (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Revenue (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - -
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 306.30 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 2.99 Bn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn 3.61 Bn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 1.17 Bn
10 Lyra Therapeutics - - - 7,000.00

Historic Data

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DateValue
Dec 31, 2025 7,000.00
Sep 30, 2025 25,000.00
Jun 30, 2025 183,000.00
Mar 31, 2025 183,000.00
Dec 31, 2024 209,000.00
Sep 30, 2024 195,000.00
Jun 30, 2024 598,000.00
Mar 31, 2024 532,000.00
Dec 31, 2023 146,000.00
Sep 30, 2023 544,000.00
Jun 30, 2023 458,000.00
Mar 31, 2023 410,000.00
Dec 31, 2022 11,000.00
Sep 30, 2022 359,000.00
Jun 30, 2022 525,000.00
Mar 31, 2022 468,000.00
Dec 31, 2021 271,000.00
Sep 30, 2021 14,000.00