Lyra Therapeutics (LYRA) Revenue (2021 - 2025)
Lyra Therapeutics (LYRA) recorded Revenue of $7,000 in Q4 2025, down 96.7% from $209,000 a year earlier and down 72.0% from the prior quarter.
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Analysis
Lyra Therapeutics (LYRA) Revenue (2021 - 2025) Analysis & Trends
For FY2025, Lyra Therapeutics reported Revenue of $398,000, down 74.1% from FY2024.
- Annual Revenue has a four-year compound annual growth rate of 8.7% (FY2021 to FY2025).
- Across earlier years, Revenue came in at $1.53 million in FY2024 (-1.5%), $1.56 million in FY2023 (+14.3%), $1.36 million in FY2022 (+378.2%) and $285,000 in FY2021.
- The Q4 2025 figure is the lowest quarterly Revenue in data going back to Q3 2021.
- On a year-over-year basis, Revenue has declined for four consecutive quarters, with an average decline of 34.9% over the last eight quarters.
- Peak year-over-year performance for Revenue in the last five years was growth of 51.5% in Q3 2023, against a decline of 96.7% in Q4 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at $25,000 (Q3 2025), $183,000 (Q2 2025) and $183,000 (Q1 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Revenue (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 645.01 Bn | 563.54 Bn | 17.26 Bn | 25.31 Bn |
| 2 | AbbVie | 465.23 Bn | 438.39 Bn | 12.70 Bn | 16.99 Bn |
| 3 | Merck | 368.40 Bn | 322.83 Bn | 12.21 Bn | 16.61 Bn |
| 4 | Novartis Ag | 278.02 Bn | 233.89 Bn | 11.24 Bn | 14.41 Bn |
| 5 | Astrazeneca | 254.57 Bn | 228.13 Bn | 12.86 Bn | 15.38 Bn |
| 6 | Amgen | 229.02 Bn | 184.42 Bn | 7.24 Bn | 10.05 Bn |
| 7 | Gilead Sciences | 187.74 Bn | 161.85 Bn | 6.22 Bn | 7.80 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 15.03 Bn |
| 9 | Vertex Pharmaceuticals | 133.45 Bn | 105.45 Bn | 2.84 Bn | 3.33 Bn |
| 10 | Lyra Therapeutics | 354,976.41 | 354,976.41 | - | 7,000.00 |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 7,000.00 |
| Sep 30, 2025 | 25,000.00 |
| Jun 30, 2025 | 183,000.00 |
| Mar 31, 2025 | 183,000.00 |
| Dec 31, 2024 | 209,000.00 |
| Sep 30, 2024 | 195,000.00 |
| Jun 30, 2024 | 598,000.00 |
| Mar 31, 2024 | 532,000.00 |
| Dec 31, 2023 | 146,000.00 |
| Sep 30, 2023 | 544,000.00 |
| Jun 30, 2023 | 458,000.00 |
| Mar 31, 2023 | 410,000.00 |
| Dec 31, 2022 | 11,000.00 |
| Sep 30, 2022 | 359,000.00 |
| Jun 30, 2022 | 525,000.00 |
| Mar 31, 2022 | 468,000.00 |
| Dec 31, 2021 | 271,000.00 |
| Sep 30, 2021 | 14,000.00 |
API Access
Lyra Therapeutics Revenue API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=revenue&ticker=LYRA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "revenue", "ticker": "LYRA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=revenue&ticker=LYRA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();