Balance Sheet
Cash Flow Statement
Asset Writedowns and ImpairmentAsset Writedowns and ImpairmentCapital ExpendituresCapital ExpendituresCash from Financing ActivitiesCash from Financing ActivitiesCash from Investing ActivitiesCash from Investing ActivitiesCash from OperationsCash from OperationsCash from RestructuringChange in Account PayablesChange in Account PayablesChange in Accured ExpensesChange in Accured ExpensesChange in CashDepreciation & Amortization (CF)Depreciation & Amortization (CF)Depreciation and DepletionDepreciation and DepletionFree Cash FlowFree Cash FlowGains from Investment SecuritiesGains from Investment SecuritiesGains from Sales and DivestituresGains from Sales and DivestituresNet Cash FlowNet Cash FlowNet IncomeNon-cash ItemsNon-cash ItemsOther financing activitiesOther financing activitiesShare-based CompensationShare-based Compensation
Growth Metrics
Income Statement
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Ratios

Lyra Therapeutics (LYRA) Change in Cash (2021 - 2025)

Lyra Therapeutics has reported Change in Cash over the past 5 years, most recently at -$6.2 million for Q4 2025.

  • Quarterly results put Change in Cash at -$6.2 million for Q4 2025, down 136.73% from a year ago — trailing twelve months through Dec 2025 was -$24.7 million (down 231.12% YoY), and the annual figure for FY2025 was -$24.7 million, down 231.12%.
  • Change in Cash for Q4 2025 was -$6.2 million at Lyra Therapeutics, up from -$7.7 million in the prior quarter.
  • Over the last five years, Change in Cash for LYRA hit a ceiling of $88.0 million in Q2 2022 and a floor of -$77.0 million in Q4 2022.
  • Median Change in Cash over the past 5 years was -$7.9 million (2024), compared with a mean of -$2.9 million.
  • Peak annual rise in Change in Cash hit 2892.28% in 2022, while the deepest fall reached 522.04% in 2022.
  • Lyra Therapeutics' Change in Cash stood at -$12.4 million in 2021, then crashed by 522.04% to -$77.0 million in 2022, then skyrocketed by 96.76% to -$2.5 million in 2023, then surged by 771.93% to $16.8 million in 2024, then tumbled by 136.73% to -$6.2 million in 2025.
  • The last three reported values for Change in Cash were -$6.2 million (Q4 2025), -$7.7 million (Q3 2025), and -$2.0 million (Q2 2025) per Business Quant data.