Denali Therapeutics (DNLI) Return on Capital Employed (2018 - 2025)

Denali Therapeutics (DNLI) has disclosed Return on Capital Employed for 8 consecutive years, with 0.55% as the latest value for Q4 2025.

  • Quarterly Return on Capital Employed fell 18.0% to 0.55% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 0.55% through Dec 2025, down 18.0% year-over-year, with the annual reading at 0.48% for FY2025, 6.0% down from the prior year.
  • Return on Capital Employed for Q4 2025 was 0.55% at Denali Therapeutics, down from 0.54% in the prior quarter.
  • The five-year high for Return on Capital Employed was 0.03% in Q2 2021, with the low at 0.55% in Q4 2025.
  • Average Return on Capital Employed over 5 years is 0.27%, with a median of 0.32% recorded in 2024.
  • The sharpest move saw Return on Capital Employed surged 43bps in 2021, then plummeted -37bps in 2022.
  • Over 5 years, Return on Capital Employed stood at 0.28% in 2021, then dropped by -23bps to 0.35% in 2022, then surged by 49bps to 0.18% in 2023, then plummeted by -111bps to 0.37% in 2024, then tumbled by -49bps to 0.55% in 2025.
  • According to Business Quant data, Return on Capital Employed over the past three periods came in at 0.55%, 0.54%, and 0.47% for Q4 2025, Q3 2025, and Q2 2025 respectively.