Denali Therapeutics DNLI
NASDAQ DNLI
$19.87 -0.46 (-2.26%)
As of: Nov 10, 2026 · 2:23 PM EST

Denali Therapeutics (DNLI) EBIT Margin (2018 - 2026)

Updated

Denali Therapeutics (DNLI) reported EBIT Margin of -712.97% for Q3 2026, up 2909.15 percentage points from the prior quarter.

Analysis

Denali Therapeutics (DNLI) EBIT Margin (2018 - 2026) Analysis & Trends

Over the twelve months ended Sep 30, 2026, Denali Therapeutics' EBIT Margin came in at -2488.14%; for FY2023, it came in at -59.51%, up 254.65 percentage points from FY2022.

  • EBIT Margin has a five-year change of -23.61 percentage points (FY2018 to FY2023).
  • By year, EBIT Margin came in at -314.16% in FY2022 (+293.62 pp), -607.78% in FY2021 (-626.46 pp), 18.69% in FY2020 (+817.79 pp) and -799.10% in FY2019 (-763.20 pp).
  • The Q3 2026 figure ranks as the highest quarterly EBIT Margin since Q2 2023.
  • The high point for year-over-year EBIT Margin in five years was Q1 2022 (a gain of 741.10 percentage points); the low point was Q3 2023 (a drop of 5961.33 percentage points).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Eli Lilly 1,264.65 Bn 1,238.27 Bn 20.46 Bn 52.42%
2 Johnson & Johnson 677.74 Bn 597.60 Bn 17.30 Bn 24.35%
3 AbbVie 517.10 Bn 485.11 Bn 13.12 Bn 36.01%
4 Merck 362.23 Bn 325.17 Bn 13.19 Bn 30.89%
5 Novartis Ag 315.90 Bn 276.16 Bn 11.24 Bn 32.97%
6 Astrazeneca 289.40 Bn 266.24 Bn 12.86 Bn 20.57%
7 Amgen 249.90 Bn 201.56 Bn 7.58 Bn 35.79%
8 Gilead Sciences 209.15 Bn 184.26 Bn 6.73 Bn 41.71%
9 Pfizer 165.88 Bn 113.23 Bn 12.56 Bn 32.98%
10 Denali Therapeutics 3.83 Bn 743.92 Mn 17.59 Mn -712.97%
Historic Data

Historic Data

Download Data
DateValue
Sep 30, 2026 -712.97%
Jun 30, 2026 -3,622.11%
Sep 30, 2023 -8,981.45%
Jun 30, 2023 57.96%
Mar 31, 2023 -343.80%
Dec 31, 2022 -1,024.45%
Sep 30, 2022 -3,020.12%
Jun 30, 2022 -117.03%
Mar 31, 2022 -157.80%
Dec 31, 2021 -616.28%
Sep 30, 2021 -1,619.55%
Jun 30, 2021 -269.48%
Mar 31, 2021 -898.90%
Dec 31, 2020 77.04%
Sep 30, 2020 -640.01%
Jun 30, 2020 -1,048.01%
Mar 31, 2020 -1,663.90%
Dec 31, 2019 -1,236.26%
Sep 30, 2019 -368.68%
Jun 30, 2019 -1,495.43%
API Access

Denali Therapeutics EBIT Margin API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=ebit-margin&ticker=DNLI&period=max&api_key=YOUR_API_KEY