Denali Therapeutics (DNLI) EBITDA (2017 - 2026)
Denali Therapeutics (DNLI) posted EBITDA of -$126.97 million for Q2 2026, compared with -$131.92 million a year earlier.
Powered by 
Analysis
Denali Therapeutics (DNLI) EBITDA (2017 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, EBITDA at Denali Therapeutics was -$530.45 million; for FY2025, it was -$544.14 million.
- In prior years, Denali Therapeutics' EBITDA was -$479.54 million in FY2024, -$179.97 million in FY2023, -$330.34 million in FY2022 and -$287.15 million in FY2021.
- The Q2 2026 figure stands as the highest quarterly EBITDA since Q3 2024.
- According to Business Quant data, EBITDA for the three prior quarters was -$134.51 million (Q1 2026), -$134.48 million (Q4 2025) and -$134.49 million (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 9.10 Bn |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 8.33 Bn |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 999.00 Mn |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 5.09 Bn |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 4.63 Bn |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -9.70 Bn |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 5.89 Bn |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 1.30 Bn |
| 10 | Denali Therapeutics | 3.35 Bn | 3.35 Bn | 3.51 Mn | -126.97 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -126.97 Mn |
| Mar 31, 2026 | -134.51 Mn |
| Dec 31, 2025 | -134.48 Mn |
| Sep 30, 2025 | -134.49 Mn |
| Jun 30, 2025 | -131.92 Mn |
| Mar 31, 2025 | -143.26 Mn |
| Dec 31, 2024 | -127.99 Mn |
| Sep 30, 2024 | -121.35 Mn |
| Jun 30, 2024 | -114.65 Mn |
| Mar 31, 2024 | -115.55 Mn |
| Dec 31, 2023 | -130.40 Mn |
| Sep 30, 2023 | -111.58 Mn |
| Jun 30, 2023 | 172.77 Mn |
| Mar 31, 2023 | -110.77 Mn |
| Dec 31, 2022 | -101.24 Mn |
| Sep 30, 2022 | -105.35 Mn |
| Jun 30, 2022 | -59.34 Mn |
| Mar 31, 2022 | -64.42 Mn |
| Dec 31, 2021 | -75.02 Mn |
| Sep 30, 2021 | -83.41 Mn |
API Access
Denali Therapeutics EBITDA API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda&ticker=DNLI&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda", "ticker": "DNLI", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda&ticker=DNLI&period=max&api_key=YOUR_API_KEY");
const data = await res.json();