Denali Therapeutics (DNLI) EPS (Basic) (2017 - 2026)

Denali Therapeutics (DNLI) posted quarterly EPS (Basic) of -$0.69 for Q1 2026, up 12.89% year-over-year from -$0.61 in Q1 2025, and up 9.19% quarter-over-quarter from -$0.76 in Q4 2025.

Denali Therapeutics (DNLI) EPS (Basic) (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has reported EPS (Basic) for 10 consecutive years, with -$0.69 the latest figure, recorded in Q1 2026.

  • In Q1 2026, EPS (Basic) rose 12.89% year-over-year to -$0.69; the TTM figure through Mar 2026 stood at -$3.01 (down 10.89% YoY), while the FY2025 annual figure was -$2.97, down 15.49% from the prior year.
  • EPS (Basic) rose to -$0.69 in Q1 2026 per DNLI's latest filing, from -$0.76 in the prior quarter.
  • Across five years, EPS (Basic) topped out at $1.34 in Q2 2023 and bottomed at -$1.0 in Q2 2025.
  • Historically, EPS (Basic) has averaged -$0.61 across 5 years, with a median of -$0.72 in 2023.
  • Annual changes were most pronounced in 2023 — EPS (Basic) surged 379.96% — and 2024, when it slumped 145.1%.
  • Denali Therapeutics' EPS (Basic) stood at -$0.79 in 2022, then slipped by 10.64% to -$0.87 in 2023, then rose by 17.81% to -$0.71 in 2024, then retreated by 6.49% to -$0.76 in 2025, then advanced by 9.19% to -$0.69 in 2026.
  • Business Quant data shows DNLI's EPS (Basic) at -$0.69 in Q1 2026, -$0.76 in Q4 2025, and -$0.75 in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 4.34
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 12.62
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 7.59
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.06
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.16
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.18
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 1.23
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -0.06
10 Denali Therapeutics 3.90 Bn 3.90 Bn 3.51 Mn -0.70

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.70
Mar 31, 2026 -0.69
Dec 31, 2025 -0.76
Sep 30, 2025 -0.75
Jun 30, 2025 -1.00
Mar 31, 2025 -0.79
Dec 31, 2024 -0.71
Sep 30, 2024 -0.65
Jun 30, 2024 -0.60
Mar 31, 2024 -0.70
Dec 31, 2023 -0.87
Sep 30, 2023 -0.72
Jun 30, 2023 1.34
Mar 31, 2023 -0.83
Dec 31, 2022 -0.79
Sep 30, 2022 -0.84
Jun 30, 2022 -0.48
Mar 31, 2022 -0.56
Dec 31, 2021 -0.62
Sep 30, 2021 -0.69