Denali Therapeutics (DNLI) Change in Acquisitions & Divestments (2017 - 2026)
Denali Therapeutics (DNLI) posted quarterly Change in Acquisitions & Divestments of $220.0 million for Q1 2026, up 36.01% year-over-year from $161.8 million in Q1 2025, and down 20.0% quarter-over-quarter from $275.0 million in Q4 2025.
Denali Therapeutics (DNLI) Change in Acquisitions & Divestments (2017 - 2026) Analysis & Trends
Denali Therapeutics (DNLI) has reported Change in Acquisitions & Divestments for 10 consecutive years, with $220.0 million the latest figure, recorded in Q1 2026.
- In Q1 2026, Change in Acquisitions & Divestments rose 36.01% year-over-year to $220.0 million; the TTM figure through Mar 2026 stood at $764.3 million (down 18.32% YoY), while the FY2025 annual figure was $706.0 million, down 38.98% from the prior year.
- Change in Acquisitions & Divestments slipped to $220.0 million in Q1 2026 per DNLI's latest filing, from $275.0 million in the prior quarter.
- Across five years, Change in Acquisitions & Divestments topped out at $601.1 million in Q3 2023 and bottomed at $107.1 million in Q3 2025.
- Historically, Change in Acquisitions & Divestments has averaged $303.0 million across 5 years, with a median of $250.5 million in 2022.
- Annual changes were most pronounced in 2023 — Change in Acquisitions & Divestments jumped 316.46% — and 2024, when it tumbled 67.06%.
- Denali Therapeutics' Change in Acquisitions & Divestments stood at $364.0 million in 2022, then soared by 34.34% to $489.0 million in 2023, then fell by 28.22% to $351.0 million in 2024, then fell by 21.65% to $275.0 million in 2025, then slipped by 20.0% to $220.0 million in 2026.
- Business Quant data shows DNLI's Change in Acquisitions & Divestments at $220.0 million in Q1 2026, $275.0 million in Q4 2025, and $107.1 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn |
| 10 | Denali Therapeutics | 3.90 Bn | 3.90 Bn | 3.51 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 197.03 Mn |
| Jun 30, 2026 | 197.03 Mn |
| Mar 31, 2026 | 220.00 Mn |
| Mar 31, 2026 | 220.00 Mn |
| Dec 31, 2025 | 275.00 Mn |
| Dec 31, 2025 | 275.00 Mn |
| Sep 30, 2025 | 107.08 Mn |
| Sep 30, 2025 | 107.08 Mn |
| Jun 30, 2025 | 162.21 Mn |
| Jun 30, 2025 | 162.21 Mn |
| Mar 31, 2025 | 161.75 Mn |
| Mar 31, 2025 | 161.75 Mn |
| Dec 31, 2024 | 351.00 Mn |
| Dec 31, 2024 | 351.00 Mn |
| Sep 30, 2024 | 198.00 Mn |
| Sep 30, 2024 | 198.00 Mn |
| Jun 30, 2024 | 225.00 Mn |
| Jun 30, 2024 | 225.00 Mn |
| Mar 31, 2024 | 383.12 Mn |
| Mar 31, 2024 | 383.12 Mn |