Denali Therapeutics (DNLI) Change in Acquisitions & Divestments (2017 - 2026)
Denali Therapeutics (DNLI) reported Change in Acquisitions & Divestments of $220.0 million for Q1 2026, up 36.01% year-over-year from $161.8 million in Q1 2025, and down 20.0% on a QoQ basis from $275.0 million in Q4 2025.
Denali Therapeutics (DNLI) has 10 years of Change in Acquisitions & Divestments data on file, last reported at $220.0 million in Q1 2026.
- Quarterly Change in Acquisitions & Divestments rose 36.01% year-over-year to $220.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $764.3 million (down 18.32% YoY) and the FY2025 annual result came in at $706.0 million, down 38.98% from the prior year.
- Change in Acquisitions & Divestments fell to $220.0 million in Q1 2026 per DNLI's latest filing, from $275.0 million in the prior quarter.
- Across five years, Change in Acquisitions & Divestments topped out at $601.1 million in Q3 2023 and bottomed at $107.1 million in Q3 2025.
- The 5-year median for Change in Acquisitions & Divestments is $250.5 million (2022), against an average of $303.0 million.
- The widest annual swing landed in 2023, when Change in Acquisitions & Divestments surged 316.46%; it then sank 67.06% in 2024.
- Tracing DNLI's Change in Acquisitions & Divestments over 5 years: stood at $364.0 million in 2022, then soared by 34.34% to $489.0 million in 2023, then slipped by 28.22% to $351.0 million in 2024, then slipped by 21.65% to $275.0 million in 2025, then fell by 20.0% to $220.0 million in 2026.
- Per Business Quant, the three latest DNLI Change in Acquisitions & Divestments figures stand at $220.0 million (Q1 2026), $275.0 million (Q4 2025), and $107.1 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn |
| 10 | Denali Therapeutics | 3.82 Bn | 3.82 Bn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 220.00 Mn |
| Mar 31, 2026 | 220.00 Mn |
| Dec 31, 2025 | 275.00 Mn |
| Dec 31, 2025 | 275.00 Mn |
| Sep 30, 2025 | 107.08 Mn |
| Sep 30, 2025 | 107.08 Mn |
| Jun 30, 2025 | 162.21 Mn |
| Jun 30, 2025 | 162.21 Mn |
| Mar 31, 2025 | 161.75 Mn |
| Mar 31, 2025 | 161.75 Mn |
| Dec 31, 2024 | 351.00 Mn |
| Dec 31, 2024 | 351.00 Mn |
| Sep 30, 2024 | 198.00 Mn |
| Sep 30, 2024 | 198.00 Mn |
| Jun 30, 2024 | 225.00 Mn |
| Jun 30, 2024 | 225.00 Mn |
| Mar 31, 2024 | 383.12 Mn |
| Mar 31, 2024 | 383.12 Mn |
| Dec 31, 2023 | 489.00 Mn |
| Dec 31, 2023 | 489.00 Mn |
| Sep 30, 2023 | 601.12 Mn |
| Sep 30, 2023 | 601.12 Mn |
| Jun 30, 2023 | 552.04 Mn |
| Jun 30, 2023 | 552.04 Mn |
| Mar 31, 2023 | 433.79 Mn |
| Mar 31, 2023 | 433.79 Mn |
| Dec 31, 2022 | 364.00 Mn |
| Dec 31, 2022 | 364.00 Mn |
| Sep 30, 2022 | 144.34 Mn |
| Sep 30, 2022 | 144.34 Mn |
| Jun 30, 2022 | 232.65 Mn |
| Jun 30, 2022 | 232.65 Mn |
| Mar 31, 2022 | 250.50 Mn |
| Mar 31, 2022 | 250.50 Mn |
| Dec 31, 2021 | 193.75 Mn |
| Dec 31, 2021 | 193.75 Mn |
| Sep 30, 2021 | 293.06 Mn |
| Sep 30, 2021 | 293.06 Mn |
| Jun 30, 2021 | 482.50 Mn |
| Jun 30, 2021 | 482.50 Mn |
| Mar 31, 2021 | 440.50 Mn |
| Mar 31, 2021 | 440.50 Mn |
| Dec 31, 2020 | 231.80 Mn |
| Dec 31, 2020 | 231.80 Mn |
| Sep 30, 2020 | 152.50 Mn |
| Sep 30, 2020 | 152.50 Mn |
| Jun 30, 2020 | 140.36 Mn |
| Jun 30, 2020 | 140.36 Mn |
| Mar 31, 2020 | 140.70 Mn |
| Mar 31, 2020 | 140.70 Mn |
| Sep 30, 2019 | 339.61 Mn |
| Sep 30, 2019 | 339.61 Mn |
| Jun 30, 2019 | 108.37 Mn |
| Jun 30, 2019 | 108.37 Mn |
| Mar 31, 2019 | 103.79 Mn |
| Mar 31, 2019 | 103.79 Mn |
| Dec 31, 2018 | 97.33 Mn |
| Dec 31, 2018 | 97.33 Mn |
| Sep 30, 2018 | 84.53 Mn |
| Sep 30, 2018 | 84.53 Mn |
| Jun 30, 2018 | 64.75 Mn |
| Jun 30, 2018 | 64.75 Mn |
| Mar 31, 2018 | 27.30 Mn |
| Mar 31, 2018 | 27.30 Mn |
| Dec 31, 2017 | 39.06 Mn |
| Dec 31, 2017 | 39.06 Mn |
| Sep 30, 2017 | 35.39 Mn |
| Sep 30, 2017 | 35.39 Mn |
| Jun 30, 2017 | 33.85 Mn |
| Jun 30, 2017 | 33.85 Mn |
| Mar 31, 2017 | 33.20 Mn |
| Mar 31, 2017 | 33.20 Mn |