Denali Therapeutics (DNLI) Change in Acquisitions & Divestments (2017 - 2026)

Denali Therapeutics (DNLI) reported Change in Acquisitions & Divestments of $220.0 million for Q1 2026, up 36.01% year-over-year from $161.8 million in Q1 2025, and down 20.0% on a QoQ basis from $275.0 million in Q4 2025.

Denali Therapeutics (DNLI) has 10 years of Change in Acquisitions & Divestments data on file, last reported at $220.0 million in Q1 2026.

  • Quarterly Change in Acquisitions & Divestments rose 36.01% year-over-year to $220.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $764.3 million (down 18.32% YoY) and the FY2025 annual result came in at $706.0 million, down 38.98% from the prior year.
  • Change in Acquisitions & Divestments fell to $220.0 million in Q1 2026 per DNLI's latest filing, from $275.0 million in the prior quarter.
  • Across five years, Change in Acquisitions & Divestments topped out at $601.1 million in Q3 2023 and bottomed at $107.1 million in Q3 2025.
  • The 5-year median for Change in Acquisitions & Divestments is $250.5 million (2022), against an average of $303.0 million.
  • The widest annual swing landed in 2023, when Change in Acquisitions & Divestments surged 316.46%; it then sank 67.06% in 2024.
  • Tracing DNLI's Change in Acquisitions & Divestments over 5 years: stood at $364.0 million in 2022, then soared by 34.34% to $489.0 million in 2023, then slipped by 28.22% to $351.0 million in 2024, then slipped by 21.65% to $275.0 million in 2025, then fell by 20.0% to $220.0 million in 2026.
  • Per Business Quant, the three latest DNLI Change in Acquisitions & Divestments figures stand at $220.0 million (Q1 2026), $275.0 million (Q4 2025), and $107.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn
10 Denali Therapeutics 3.82 Bn 3.82 Bn -

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 220.00 Mn
Mar 31, 2026 220.00 Mn
Dec 31, 2025 275.00 Mn
Dec 31, 2025 275.00 Mn
Sep 30, 2025 107.08 Mn
Sep 30, 2025 107.08 Mn
Jun 30, 2025 162.21 Mn
Jun 30, 2025 162.21 Mn
Mar 31, 2025 161.75 Mn
Mar 31, 2025 161.75 Mn
Dec 31, 2024 351.00 Mn
Dec 31, 2024 351.00 Mn
Sep 30, 2024 198.00 Mn
Sep 30, 2024 198.00 Mn
Jun 30, 2024 225.00 Mn
Jun 30, 2024 225.00 Mn
Mar 31, 2024 383.12 Mn
Mar 31, 2024 383.12 Mn
Dec 31, 2023 489.00 Mn
Dec 31, 2023 489.00 Mn
Sep 30, 2023 601.12 Mn
Sep 30, 2023 601.12 Mn
Jun 30, 2023 552.04 Mn
Jun 30, 2023 552.04 Mn
Mar 31, 2023 433.79 Mn
Mar 31, 2023 433.79 Mn
Dec 31, 2022 364.00 Mn
Dec 31, 2022 364.00 Mn
Sep 30, 2022 144.34 Mn
Sep 30, 2022 144.34 Mn
Jun 30, 2022 232.65 Mn
Jun 30, 2022 232.65 Mn
Mar 31, 2022 250.50 Mn
Mar 31, 2022 250.50 Mn
Dec 31, 2021 193.75 Mn
Dec 31, 2021 193.75 Mn
Sep 30, 2021 293.06 Mn
Sep 30, 2021 293.06 Mn
Jun 30, 2021 482.50 Mn
Jun 30, 2021 482.50 Mn
Mar 31, 2021 440.50 Mn
Mar 31, 2021 440.50 Mn
Dec 31, 2020 231.80 Mn
Dec 31, 2020 231.80 Mn
Sep 30, 2020 152.50 Mn
Sep 30, 2020 152.50 Mn
Jun 30, 2020 140.36 Mn
Jun 30, 2020 140.36 Mn
Mar 31, 2020 140.70 Mn
Mar 31, 2020 140.70 Mn
Sep 30, 2019 339.61 Mn
Sep 30, 2019 339.61 Mn
Jun 30, 2019 108.37 Mn
Jun 30, 2019 108.37 Mn
Mar 31, 2019 103.79 Mn
Mar 31, 2019 103.79 Mn
Dec 31, 2018 97.33 Mn
Dec 31, 2018 97.33 Mn
Sep 30, 2018 84.53 Mn
Sep 30, 2018 84.53 Mn
Jun 30, 2018 64.75 Mn
Jun 30, 2018 64.75 Mn
Mar 31, 2018 27.30 Mn
Mar 31, 2018 27.30 Mn
Dec 31, 2017 39.06 Mn
Dec 31, 2017 39.06 Mn
Sep 30, 2017 35.39 Mn
Sep 30, 2017 35.39 Mn
Jun 30, 2017 33.85 Mn
Jun 30, 2017 33.85 Mn
Mar 31, 2017 33.20 Mn
Mar 31, 2017 33.20 Mn