Denali Therapeutics (DNLI) Change in Acquisitions & Divestments (2017 - 2026)

Denali Therapeutics (DNLI) posted quarterly Change in Acquisitions & Divestments of $220.0 million for Q1 2026, up 36.01% year-over-year from $161.8 million in Q1 2025, and down 20.0% quarter-over-quarter from $275.0 million in Q4 2025.

Denali Therapeutics (DNLI) Change in Acquisitions & Divestments (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has reported Change in Acquisitions & Divestments for 10 consecutive years, with $220.0 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Change in Acquisitions & Divestments rose 36.01% year-over-year to $220.0 million; the TTM figure through Mar 2026 stood at $764.3 million (down 18.32% YoY), while the FY2025 annual figure was $706.0 million, down 38.98% from the prior year.
  • Change in Acquisitions & Divestments slipped to $220.0 million in Q1 2026 per DNLI's latest filing, from $275.0 million in the prior quarter.
  • Across five years, Change in Acquisitions & Divestments topped out at $601.1 million in Q3 2023 and bottomed at $107.1 million in Q3 2025.
  • Historically, Change in Acquisitions & Divestments has averaged $303.0 million across 5 years, with a median of $250.5 million in 2022.
  • Annual changes were most pronounced in 2023 — Change in Acquisitions & Divestments jumped 316.46% — and 2024, when it tumbled 67.06%.
  • Denali Therapeutics' Change in Acquisitions & Divestments stood at $364.0 million in 2022, then soared by 34.34% to $489.0 million in 2023, then fell by 28.22% to $351.0 million in 2024, then fell by 21.65% to $275.0 million in 2025, then slipped by 20.0% to $220.0 million in 2026.
  • Business Quant data shows DNLI's Change in Acquisitions & Divestments at $220.0 million in Q1 2026, $275.0 million in Q4 2025, and $107.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn
7 Royalty Pharma 33.72 Bn 35.84 Bn -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn
10 Denali Therapeutics 3.90 Bn 3.90 Bn 3.51 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 197.03 Mn
Jun 30, 2026 197.03 Mn
Mar 31, 2026 220.00 Mn
Mar 31, 2026 220.00 Mn
Dec 31, 2025 275.00 Mn
Dec 31, 2025 275.00 Mn
Sep 30, 2025 107.08 Mn
Sep 30, 2025 107.08 Mn
Jun 30, 2025 162.21 Mn
Jun 30, 2025 162.21 Mn
Mar 31, 2025 161.75 Mn
Mar 31, 2025 161.75 Mn
Dec 31, 2024 351.00 Mn
Dec 31, 2024 351.00 Mn
Sep 30, 2024 198.00 Mn
Sep 30, 2024 198.00 Mn
Jun 30, 2024 225.00 Mn
Jun 30, 2024 225.00 Mn
Mar 31, 2024 383.12 Mn
Mar 31, 2024 383.12 Mn