Denali Therapeutics (DNLI) EPS (Weighted Average and Diluted) (2018 - 2026)

Denali Therapeutics (DNLI) reported EPS (Weighted Average and Diluted) of -$0.69 for Q1 2026, up 11.54% year-over-year from -$0.62 in Q1 2025, and up 5.48% on a QoQ basis from -$0.73 in Q4 2025.

Denali Therapeutics (DNLI) has 9 years of EPS (Weighted Average and Diluted) data on file, last reported at -$0.69 in Q1 2026.

  • Quarterly EPS (Weighted Average and Diluted) rose 11.54% year-over-year to -$0.69 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$2.88 (down 7.46% YoY) and the FY2025 annual result came in at -$2.97, down 15.56% from the prior year.
  • EPS (Weighted Average and Diluted) climbed to -$0.69 in Q1 2026 per DNLI's latest filing, from -$0.73 in the prior quarter.
  • Across five years, EPS (Weighted Average and Diluted) topped out at $1.3 in Q2 2023 and bottomed at -$0.87 in Q4 2023.
  • The 5-year median for EPS (Weighted Average and Diluted) is -$0.72 (2023), against an average of -$0.58.
  • The widest annual swing landed in 2023, when EPS (Weighted Average and Diluted) surged 370.83%; it then tumbled 145.38% in 2024.
  • Tracing DNLI's EPS (Weighted Average and Diluted) over 5 years: stood at -$0.75 in 2022, then slipped by 16.0% to -$0.87 in 2023, then climbed by 21.84% to -$0.68 in 2024, then slipped by 7.35% to -$0.73 in 2025, then gained by 5.48% to -$0.69 in 2026.
  • Per Business Quant, the three latest DNLI EPS (Weighted Average and Diluted) figures stand at -$0.69 (Q1 2026), -$0.73 (Q4 2025), and -$0.74 (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Weighted Avg. Diluted) (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -4.43
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 3,086.42
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - 0.00
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 4.02
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 6.75
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 1.51
10 Denali Therapeutics 3.82 Bn 3.82 Bn - -0.69

Historic Data

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DateValue
Mar 31, 2026 -0.69
Dec 31, 2025 -0.73
Sep 30, 2025 -0.74
Jun 30, 2025 -0.72
Mar 31, 2025 -0.78
Dec 31, 2024 -0.68
Sep 30, 2024 -0.63
Jun 30, 2024 -0.59
Mar 31, 2024 -0.68
Dec 31, 2023 -0.87
Sep 30, 2023 -0.72
Jun 30, 2023 1.30
Mar 31, 2023 -0.80
Dec 31, 2022 -0.75
Sep 30, 2022 -0.84
Jun 30, 2022 -0.48
Mar 31, 2022 -0.53
Dec 31, 2021 -0.62
Sep 30, 2021 -0.69
Jun 30, 2021 -0.50
Mar 31, 2021 -0.58
Dec 31, 2020 2.28
Sep 30, 2020 -0.54
Jun 30, 2020 -0.56
Mar 31, 2020 -0.55
Dec 31, 2019 -0.60
Dec 31, 2018 0.84