Denali Therapeutics (DNLI) Change in Cash (2017 - 2026)

Denali Therapeutics (DNLI) reported Change in Cash of $182.3 million for Q1 2026, up 256.5% year-over-year from $51.1 million in Q1 2025, and up 59.4% quarter-over-quarter from $114.4 million in Q4 2025.

Denali Therapeutics (DNLI) Change in Cash (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has 10 years of Change in Cash data on file, last reported at $182.3 million in Q1 2026.

  • Change in Cash for Q1 2026 came in at $182.3 million, up 256.5% year-over-year; the trailing twelve-month figure through Mar 2026 was $330.7 million (up 15876.67% YoY), and the FY2025 annual result was $31.9 million, down 33.35% from the prior year.
  • Change in Cash improved to $182.3 million in Q1 2026 per DNLI's latest filing, from $114.4 million in the prior quarter.
  • Over five years, Change in Cash peaked at $182.3 million in Q1 2026 and troughed at -$188.5 million in Q1 2022.
  • A 5-year average of $5.6 million and a median of $16.0 million in 2024 frame the typical range for Change in Cash.
  • The sharpest annual moves came in 2024 and 2025: Change in Cash surged 503.37% in 2024, then plunged 414.87% in 2025.
  • A 5-year view of Change in Cash shows it stood at $99.4 million in 2022, then plunged by 121.03% to -$20.9 million in 2023, then surged by 503.37% to $84.3 million in 2024, then jumped by 35.62% to $114.4 million in 2025, then soared by 59.4% to $182.3 million in 2026.
  • Business Quant data shows DNLI's Change in Cash at $182.3 million in Q1 2026, $114.4 million in Q4 2025, and -$50.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Denali Therapeutics 4.35 Bn 4.35 Bn - 182.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 182.30 Mn
Dec 31, 2025 114.36 Mn
Sep 30, 2025 -50.24 Mn
Jun 30, 2025 84.26 Mn
Mar 31, 2025 -116.48 Mn
Dec 31, 2024 84.32 Mn
Sep 30, 2024 15.96 Mn
Jun 30, 2024 14.11 Mn
Mar 31, 2024 -66.53 Mn
Dec 31, 2023 -20.91 Mn
Sep 30, 2023 16.04 Mn
Jun 30, 2023 63.92 Mn
Mar 31, 2023 -149.91 Mn
Dec 31, 2022 99.43 Mn
Sep 30, 2022 -36.47 Mn
Jun 30, 2022 50.14 Mn
Mar 31, 2022 -188.52 Mn
Dec 31, 2021 -101.08 Mn
Sep 30, 2021 -91.13 Mn
Jun 30, 2021 50.36 Mn