Denali Therapeutics (DNLI) Change in Cash (2017 - 2026)
Denali Therapeutics (DNLI) reported Change in Cash of $182.3 million for Q1 2026, up 256.5% year-over-year from $51.1 million in Q1 2025, and up 59.4% on a QoQ basis from $114.4 million in Q4 2025.
Denali Therapeutics (DNLI) has 10 years of Change in Cash data on file, last reported at $182.3 million in Q1 2026.
- Quarterly Change in Cash rose 256.5% year-over-year to $182.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $330.7 million (up 15876.67% YoY) and the FY2025 annual result came in at $31.9 million, down 33.35% from the prior year.
- Change in Cash rose to $182.3 million in Q1 2026 per DNLI's latest filing, from $114.4 million in the prior quarter.
- Across five years, Change in Cash topped out at $182.3 million in Q1 2026 and bottomed at -$188.5 million in Q1 2022.
- The 5-year median for Change in Cash is $16.0 million (2024), against an average of $5.6 million.
- The widest annual swing landed in 2024, when Change in Cash soared 503.37%; it then slumped 414.87% in 2025.
- Tracing DNLI's Change in Cash over 5 years: stood at $99.4 million in 2022, then slumped by 121.03% to -$20.9 million in 2023, then soared by 503.37% to $84.3 million in 2024, then surged by 35.62% to $114.4 million in 2025, then jumped by 59.4% to $182.3 million in 2026.
- Per Business Quant, the three latest DNLI Change in Cash figures stand at $182.3 million (Q1 2026), $114.4 million (Q4 2025), and -$50.2 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 623.00 Mn |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 417.10 Mn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | -153.10 Mn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 53.61 Mn |
| 10 | Denali Therapeutics | 3.82 Bn | 3.82 Bn | - | 182.30 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 182.30 Mn |
| Dec 31, 2025 | 114.36 Mn |
| Sep 30, 2025 | -50.24 Mn |
| Jun 30, 2025 | 84.26 Mn |
| Mar 31, 2025 | -116.48 Mn |
| Dec 31, 2024 | 84.32 Mn |
| Sep 30, 2024 | 15.96 Mn |
| Jun 30, 2024 | 14.11 Mn |
| Mar 31, 2024 | -66.53 Mn |
| Dec 31, 2023 | -20.91 Mn |
| Sep 30, 2023 | 16.04 Mn |
| Jun 30, 2023 | 63.92 Mn |
| Mar 31, 2023 | -149.91 Mn |
| Dec 31, 2022 | 99.43 Mn |
| Sep 30, 2022 | -36.47 Mn |
| Jun 30, 2022 | 50.14 Mn |
| Mar 31, 2022 | -188.52 Mn |
| Dec 31, 2021 | -101.08 Mn |
| Sep 30, 2021 | -91.13 Mn |
| Jun 30, 2021 | 50.36 Mn |
| Mar 31, 2021 | -71.82 Mn |
| Dec 31, 2020 | 156.10 Mn |
| Sep 30, 2020 | 213.86 Mn |
| Jun 30, 2020 | -70.35 Mn |
| Mar 31, 2020 | 128.09 Mn |
| Sep 30, 2019 | 5.55 Mn |
| Jun 30, 2019 | 23.28 Mn |
| Mar 31, 2019 | -37.46 Mn |
| Dec 31, 2018 | 33.47 Mn |
| Sep 30, 2018 | 10.56 Mn |
| Jun 30, 2018 | -9.86 Mn |
| Mar 31, 2018 | -174.46 Mn |
| Dec 31, 2017 | 182.11 Mn |
| Sep 30, 2017 | -5.04 Mn |
| Jun 30, 2017 | 4.56 Mn |
| Mar 31, 2017 | -3.10 Mn |