Denali Therapeutics DNLI
NASDAQ DNLI
$22.28 -0.52 (-2.28%)
As of: Sep 4, 2026 · 3:59 PM EDT

Denali Therapeutics (DNLI) Change in Cash (2017 - 2026)

Denali Therapeutics (DNLI) posted quarterly Change in Cash of $182.3 million for Q1 2026, up 256.5% year-over-year from $51.1 million in Q1 2025, and up 59.4% quarter-over-quarter from $114.4 million in Q4 2025.

Analysis

Denali Therapeutics (DNLI) Change in Cash (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has reported Change in Cash for 10 consecutive years, with $182.3 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Change in Cash rose 256.5% year-over-year to $182.3 million; the TTM figure through Mar 2026 stood at $330.7 million (up 15876.67% YoY), while the FY2025 annual figure was $31.9 million, down 33.35% from the prior year.
  • Change in Cash advanced to $182.3 million in Q1 2026 per DNLI's latest filing, from $114.4 million in the prior quarter.
  • Across five years, Change in Cash topped out at $182.3 million in Q1 2026 and bottomed at -$188.5 million in Q1 2022.
  • Historically, Change in Cash has averaged $5.6 million across 5 years, with a median of $16.0 million in 2024.
  • Annual changes were most pronounced in 2024 — Change in Cash surged 503.37% — and 2025, when it plunged 414.87%.
  • Denali Therapeutics' Change in Cash stood at $99.4 million in 2022, then sank by 121.03% to -$20.9 million in 2023, then soared by 503.37% to $84.3 million in 2024, then surged by 35.62% to $114.4 million in 2025, then jumped by 59.4% to $182.3 million in 2026.
  • Business Quant data shows DNLI's Change in Cash at $182.3 million in Q1 2026, $114.4 million in Q4 2025, and -$50.2 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 649.20 Mn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn -504.60 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -185.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - 374.50 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 427.25 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn -2.94 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 225.59 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -37.42 Mn
10 Denali Therapeutics 4.18 Bn 4.18 Bn 3.51 Mn -186.10 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -186.10 Mn
Mar 31, 2026 182.30 Mn
Dec 31, 2025 114.36 Mn
Sep 30, 2025 -50.24 Mn
Jun 30, 2025 84.26 Mn
Mar 31, 2025 -116.48 Mn
Dec 31, 2024 84.32 Mn
Sep 30, 2024 15.96 Mn
Jun 30, 2024 14.11 Mn
Mar 31, 2024 -66.53 Mn
Dec 31, 2023 -20.91 Mn
Sep 30, 2023 16.04 Mn
Jun 30, 2023 63.92 Mn
Mar 31, 2023 -149.91 Mn
Dec 31, 2022 99.43 Mn
Sep 30, 2022 -36.47 Mn
Jun 30, 2022 50.14 Mn
Mar 31, 2022 -188.52 Mn
Dec 31, 2021 -101.08 Mn
Sep 30, 2021 -91.13 Mn