Denali Therapeutics (DNLI) Retained Earnings (2017 - 2026)

Denali Therapeutics (DNLI) posted quarterly Retained Earnings of -$682000.0 for Q1 2026, down 100.02% year-over-year from $2.8 billion in Q1 2025, and down 200.0% quarter-over-quarter from $682000.0 in Q4 2025.

Denali Therapeutics (DNLI) Retained Earnings (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has reported Retained Earnings for 10 consecutive years, with -$682000.0 the latest figure, recorded in Q1 2026.

  • In Q1 2026, Retained Earnings fell 100.02% year-over-year to -$682000.0; the TTM figure through Mar 2026 stood at -$682000.0 (down 100.02% YoY), while the FY2025 annual figure was $682000.0, up 100.04% from the prior year.
  • Retained Earnings eased to -$682000.0 in Q1 2026 per DNLI's latest filing, from $682000.0 in the prior quarter.
  • Across five years, Retained Earnings topped out at $2.8 billion in Q1 2025 and bottomed at -$1.9 billion in Q3 2025.
  • Historically, Retained Earnings has averaged -$430.0 million across 5 years, with a median of -$872.3 million in 2022.
  • On a YoY basis, Retained Earnings climbed as much as 705203.45% in 2022 and fell as far as 167329.75% in 2022.
  • Denali Therapeutics' Retained Earnings stood at -$971.0 million in 2022, then decreased by 14.96% to -$1.1 billion in 2023, then sank by 37.88% to -$1.5 billion in 2024, then soared by 100.04% to $682000.0 in 2025, then slumped by 200.0% to -$682000.0 in 2026.
  • Business Quant data shows DNLI's Retained Earnings at -$682000.0 in Q1 2026, $682000.0 in Q4 2025, and -$1.9 billion in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 15.69 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 37.62 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 1.41 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -4.00 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.05 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -104.13 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 4.38 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -6.33 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 6.57 Bn
10 Denali Therapeutics 3.90 Bn 3.90 Bn 3.51 Mn 3.14 Bn

Historic Data

Download Data
DateValue
Jun 30, 2026 3.14 Bn
Mar 31, 2026 -682,000.00
Dec 31, 2025 682,000.00
Sep 30, 2025 -1.92 Bn
Jun 30, 2025 -1.80 Bn
Mar 31, 2025 2.79 Bn
Dec 31, 2024 -1.54 Bn
Sep 30, 2024 -1.42 Bn
Jun 30, 2024 -2.66 Mn
Mar 31, 2024 -1.30 Mn
Dec 31, 2023 -1.12 Bn
Sep 30, 2023 -996.74 Mn
Jun 30, 2023 -1.44 Mn
Mar 31, 2023 -1.08 Bn
Dec 31, 2022 -970.99 Mn
Sep 30, 2022 -872.31 Mn
Jun 30, 2022 -12.27 Mn
Mar 31, 2022 1.64 Bn
Dec 31, 2021 -645.00 Mn
Sep 30, 2021 -521,000.00