Denali Therapeutics (DNLI) Retained Earnings (2017 - 2026)

Denali Therapeutics (DNLI) reported Retained Earnings of -$682000.0 for Q1 2026, down 133.48% year-over-year from $2.0 million in Q1 2025, and up 99.97% quarter-over-quarter from -$2.1 billion in Q4 2025.

Denali Therapeutics (DNLI) Retained Earnings (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has 10 years of Retained Earnings data on file, last reported at -$682000.0 in Q1 2026.

  • Retained Earnings for Q1 2026 came in at -$682000.0, down 133.48% year-over-year; the trailing twelve-month figure through Mar 2026 was -$682000.0 (down 133.48% YoY), and the FY2025 annual result was -$2.1 billion, down 33.3% from the prior year.
  • Retained Earnings climbed to -$682000.0 in Q1 2026 per DNLI's latest filing, from -$2.1 billion in the prior quarter.
  • Over five years, Retained Earnings peaked at $2.0 million in Q1 2025 and troughed at -$2.1 billion in Q4 2025.
  • A 5-year average of -$674.4 million and a median of -$769.0 million in 2022 frame the typical range for Retained Earnings.
  • The sharpest annual moves came in 2022 and 2025: Retained Earnings plunged 208870.11% in 2022, then jumped 257.18% in 2025.
  • A 5-year view of Retained Earnings shows it stood at -$6.9 million in 2022, then tumbled by 16109.86% to -$1.1 billion in 2023, then plunged by 37.88% to -$1.5 billion in 2024, then plunged by 33.3% to -$2.1 billion in 2025, then jumped by 99.97% to -$682000.0 in 2026.
  • Business Quant data shows DNLI's Retained Earnings at -$682000.0 in Q1 2026, -$2.1 billion in Q4 2025, and $1.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -153.89 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -211.85 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 1.00 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 130.89 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -279.00 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -1.88
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 14.59 Bn
9 Abivax 91.96 Bn 91.96 Bn - -838.07 Mn
10 Denali Therapeutics 4.35 Bn 4.35 Bn - -682,000.00

Historic Data

Download Data
DateValue
Mar 31, 2026 -682,000.00
Dec 31, 2025 -2.05 Bn
Sep 30, 2025 1.10 Mn
Jun 30, 2025 939,000.00
Mar 31, 2025 2.04 Mn
Dec 31, 2024 -1.54 Bn
Sep 30, 2024 -1.42 Bn
Jun 30, 2024 -2.66 Mn
Mar 31, 2024 -1.30 Mn
Dec 31, 2023 -1.12 Bn
Sep 30, 2023 -996.74 Mn
Jun 30, 2023 -897.39 Mn
Mar 31, 2023 -1.08 Bn
Dec 31, 2022 -6.89 Mn
Sep 30, 2022 -872.31 Mn
Jun 30, 2022 -769.01 Mn
Mar 31, 2022 -710.22 Mn
Dec 31, 2021 -2.50 Mn
Sep 30, 2021 -521,000.00
Jun 30, 2021 -368,000.00