Denali Therapeutics (DNLI) Retained Earnings (2017 - 2026)

Denali Therapeutics (DNLI) reported Retained Earnings of -$682000.0 for Q1 2026, down 133.48% year-over-year from $2.0 million in Q1 2025, and up 99.97% on a QoQ basis from -$2.1 billion in Q4 2025.

Denali Therapeutics (DNLI) has 10 years of Retained Earnings data on file, last reported at -$682000.0 in Q1 2026.

  • Quarterly Retained Earnings fell 133.48% year-over-year to -$682000.0 in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$682000.0 (down 133.48% YoY) and the FY2025 annual result came in at -$2.1 billion, down 33.3% from the prior year.
  • Retained Earnings improved to -$682000.0 in Q1 2026 per DNLI's latest filing, from -$2.1 billion in the prior quarter.
  • Across five years, Retained Earnings topped out at $2.0 million in Q1 2025 and bottomed at -$2.1 billion in Q4 2025.
  • The 5-year median for Retained Earnings is -$769.0 million (2022), against an average of -$674.4 million.
  • The widest annual swing landed in 2022, when Retained Earnings slumped 208870.11%; it then surged 257.18% in 2025.
  • Tracing DNLI's Retained Earnings over 5 years: stood at -$6.9 million in 2022, then sank by 16109.86% to -$1.1 billion in 2023, then slumped by 37.88% to -$1.5 billion in 2024, then slumped by 33.3% to -$2.1 billion in 2025, then surged by 99.97% to -$682000.0 in 2026.
  • Per Business Quant, the three latest DNLI Retained Earnings figures stand at -$682000.0 (Q1 2026), -$2.1 billion (Q4 2025), and $1.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Retained Earnings (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -211.85 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -153.89 Mn
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 1.00 Bn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -438.66 Mn
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -279.00 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 14.59 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - 130.89 Mn
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 36.42 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn -24.89 Mn
10 Denali Therapeutics 3.82 Bn 3.82 Bn - -682,000.00

Historic Data

Download Data 🔒
DateValue
Mar 31, 2026 -682,000.00
Dec 31, 2025 -2.05 Bn
Sep 30, 2025 1.10 Mn
Jun 30, 2025 939,000.00
Mar 31, 2025 2.04 Mn
Dec 31, 2024 -1.54 Bn
Sep 30, 2024 -1.42 Bn
Jun 30, 2024 -2.66 Mn
Mar 31, 2024 -1.30 Mn
Dec 31, 2023 -1.12 Bn
Sep 30, 2023 -996.74 Mn
Jun 30, 2023 -897.39 Mn
Mar 31, 2023 -1.08 Bn
Dec 31, 2022 -6.89 Mn
Sep 30, 2022 -872.31 Mn
Jun 30, 2022 -769.01 Mn
Mar 31, 2022 -710.22 Mn
Dec 31, 2021 -2.50 Mn
Sep 30, 2021 -521,000.00
Jun 30, 2021 -368,000.00
Mar 31, 2021 -424.46 Mn
Dec 31, 2020 -245,000.00
Sep 30, 2020 11,000.00
Jun 30, 2020 551,000.00
Mar 31, 2020 835,000.00
Dec 31, 2019 -425.55 Mn
Sep 30, 2019 -371.53 Mn
Jun 30, 2019 -325.27 Mn
Mar 31, 2019 332,000.00
Dec 31, 2018 -649,000.00
Sep 30, 2018 -1.42 Mn
Jun 30, 2018 -270.10 Mn
Mar 31, 2018 -1.29 Mn
Dec 31, 2017 -191.70 Mn