Denali Therapeutics (DNLI) Invested Capital (2017 - 2026)
Denali Therapeutics (DNLI) reported Invested Capital of $926.1 million for Q1 2026, down 18.13% year-over-year from $1.1 billion in Q1 2025, and down 9.15% on a QoQ basis from $1.0 billion in Q4 2025.
Denali Therapeutics (DNLI) has 10 years of Invested Capital data on file, last reported at $926.1 million in Q1 2026.
- Quarterly Invested Capital fell 18.13% year-over-year to $926.1 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $926.1 million (down 18.13% YoY) and the FY2025 annual result came in at $1.0 billion, down 17.73% from the prior year.
- Invested Capital declined to $926.1 million in Q1 2026 per DNLI's latest filing, from $1.0 billion in the prior quarter.
- Across five years, Invested Capital topped out at $1.5 billion in Q1 2024 and bottomed at $812.7 million in Q3 2022.
- The 5-year median for Invested Capital is $1.0 billion (2025), against an average of $1.1 billion.
- The widest annual swing landed in 2024, when Invested Capital soared 50.56%; it then slipped 29.63% in 2025.
- Tracing DNLI's Invested Capital over 5 years: stood at $1.0 billion in 2022, then fell by 1.52% to $1.0 billion in 2023, then gained by 20.18% to $1.2 billion in 2024, then slipped by 17.73% to $1.0 billion in 2025, then decreased by 9.15% to $926.1 million in 2026.
- Per Business Quant, the three latest DNLI Invested Capital figures stand at $926.1 million (Q1 2026), $1.0 billion (Q4 2025), and $931.8 million (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Invested Cap. (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | 595,226.00 |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | - |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | 110.96 Mn |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | 14.38 Mn |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 19.36 Bn |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 31.42 Bn |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 1.08 Bn |
| 10 | Denali Therapeutics | 3.82 Bn | 3.82 Bn | - | 926.10 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 926.10 Mn |
| Dec 31, 2025 | 1.02 Bn |
| Sep 30, 2025 | 931.83 Mn |
| Jun 30, 2025 | 1.03 Bn |
| Mar 31, 2025 | 1.13 Bn |
| Dec 31, 2024 | 1.24 Bn |
| Sep 30, 2024 | 1.32 Bn |
| Jun 30, 2024 | 1.39 Bn |
| Mar 31, 2024 | 1.46 Bn |
| Dec 31, 2023 | 1.03 Bn |
| Sep 30, 2023 | 1.12 Bn |
| Jun 30, 2023 | 1.19 Bn |
| Mar 31, 2023 | 966.71 Mn |
| Dec 31, 2022 | 1.05 Bn |
| Sep 30, 2022 | 812.75 Mn |
| Jun 30, 2022 | 884.45 Mn |
| Mar 31, 2022 | 920.64 Mn |
| Dec 31, 2021 | 962.29 Mn |
| Sep 30, 2021 | 1.01 Bn |
| Jun 30, 2021 | 1.07 Bn |
| Mar 31, 2021 | 1.11 Bn |
| Dec 31, 2020 | 1.15 Bn |
| Sep 30, 2020 | 882.55 Mn |
| Jun 30, 2020 | 502.17 Mn |
| Mar 31, 2020 | 545.31 Mn |
| Dec 31, 2019 | 394.89 Mn |
| Sep 30, 2019 | 438.20 Mn |
| Jun 30, 2019 | 475.17 Mn |
| Mar 31, 2019 | 516.65 Mn |
| Dec 31, 2018 | 546.85 Mn |
| Sep 30, 2018 | 461.18 Mn |
| Jun 30, 2018 | 490.27 Mn |
| Mar 31, 2018 | 539.03 Mn |
| Dec 31, 2017 | 465.80 Mn |