Denali Therapeutics (DNLI) Invested Capital (2017 - 2026)

Denali Therapeutics (DNLI) reported Invested Capital of $926.1 million for Q1 2026, down 18.13% year-over-year from $1.1 billion in Q1 2025, and down 9.15% quarter-over-quarter from $1.0 billion in Q4 2025.

Denali Therapeutics (DNLI) Invested Capital (2017 - 2026) Analysis & Trends

Denali Therapeutics (DNLI) has 10 years of Invested Capital data on file, last reported at $926.1 million in Q1 2026.

  • Invested Capital for Q1 2026 came in at $926.1 million, down 18.13% year-over-year; the trailing twelve-month figure through Mar 2026 was $926.1 million (down 18.13% YoY), and the FY2025 annual result was $1.0 billion, down 17.73% from the prior year.
  • Invested Capital eased to $926.1 million in Q1 2026 per DNLI's latest filing, from $1.0 billion in the prior quarter.
  • Over five years, Invested Capital peaked at $1.5 billion in Q1 2024 and troughed at $812.7 million in Q3 2022.
  • A 5-year average of $1.1 billion and a median of $1.0 billion in 2025 frame the typical range for Invested Capital.
  • The sharpest annual moves came in 2024 and 2025: Invested Capital surged 50.56% in 2024, then declined 29.63% in 2025.
  • A 5-year view of Invested Capital shows it stood at $1.0 billion in 2022, then decreased by 1.52% to $1.0 billion in 2023, then climbed by 20.18% to $1.2 billion in 2024, then declined by 17.73% to $1.0 billion in 2025, then dropped by 9.15% to $926.1 million in 2026.
  • Business Quant data shows DNLI's Invested Capital at $926.1 million in Q1 2026, $1.0 billion in Q4 2025, and $931.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 7.14 Bn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 795.79 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 595,226.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 1.00 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 14.38 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 19.36 Bn
9 Abivax 91.96 Bn 91.96 Bn - 502.95 Mn
10 Denali Therapeutics 4.35 Bn 4.35 Bn - 926.10 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 926.10 Mn
Dec 31, 2025 1.02 Bn
Sep 30, 2025 931.83 Mn
Jun 30, 2025 1.03 Bn
Mar 31, 2025 1.13 Bn
Dec 31, 2024 1.24 Bn
Sep 30, 2024 1.32 Bn
Jun 30, 2024 1.39 Bn
Mar 31, 2024 1.46 Bn
Dec 31, 2023 1.03 Bn
Sep 30, 2023 1.12 Bn
Jun 30, 2023 1.19 Bn
Mar 31, 2023 966.71 Mn
Dec 31, 2022 1.05 Bn
Sep 30, 2022 812.75 Mn
Jun 30, 2022 884.45 Mn
Mar 31, 2022 920.64 Mn
Dec 31, 2021 962.29 Mn
Sep 30, 2021 1.01 Bn
Jun 30, 2021 1.07 Bn