Denali Therapeutics (DNLI) Free Cash Flow (2017 - 2026)
Denali Therapeutics' (DNLI) quarterly Free Cash Flow came in at -$133.7 million in Q1 2026, up 2.11% year-on-year from -$130.9 million in Q1 2025, and down 22.25% on a QoQ basis from -$109.3 million in Q4 2025.
Denali Therapeutics (DNLI) Free Cash Flow (2017 - 2026) Analysis & Trends
Denali Therapeutics (DNLI) has 10 years of Free Cash Flow data on file, last reported at -$133.7 million in Q1 2026.
- On a quarterly basis, Free Cash Flow rose 2.11% year-over-year to -$133.7 million in Q1 2026; TTM through Mar 2026 was -$419.2 million, a 13.41% decrease from a year earlier, with the FY2025 full-year figure at -$422.1 million, down 20.99% from the prior year.
- Free Cash Flow for Q1 2026 stood at -$133.7 million, down from -$109.3 million in the prior quarter.
- Over the last five years, Free Cash Flow for DNLI reached as high as -$49.7 million in Q2 2022 and fell as low as -$136.5 million in Q1 2025.
- Historically, Free Cash Flow has averaged -$89.4 million across 5 years, with a median of -$83.7 million in 2024.
- Across the five-year window, Free Cash Flow sank 132.77% in 2023 and soared 32.19% in 2024, its largest moves.
- Year by year, Free Cash Flow stood at -$72.4 million in 2022, then tumbled by 54.18% to -$111.6 million in 2023, then gained by 24.97% to -$83.7 million in 2024, then tumbled by 30.59% to -$109.3 million in 2025, then dropped by 22.25% to -$133.7 million in 2026.
- Per Business Quant data, the three most recent Free Cash Flow figures were -$133.7 million in Q1 2026, -$109.3 million in Q4 2025, and -$96.6 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Free Cash Flow (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -19.58 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -2.49 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 158.09 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.29 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 848.30 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -354.95 Mn |
| 10 | Denali Therapeutics | 4.33 Bn | 4.33 Bn | - | -133.67 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -133.67 Mn |
| Mar 31, 2026 | -133.67 Mn |
| Dec 31, 2025 | -109.35 Mn |
| Dec 31, 2025 | -109.35 Mn |
| Sep 30, 2025 | -96.64 Mn |
| Sep 30, 2025 | -96.64 Mn |
| Jun 30, 2025 | -79.58 Mn |
| Jun 30, 2025 | -79.58 Mn |
| Mar 31, 2025 | -136.55 Mn |
| Mar 31, 2025 | -136.55 Mn |
| Dec 31, 2024 | -83.73 Mn |
| Dec 31, 2024 | -83.73 Mn |
| Sep 30, 2024 | -53.38 Mn |
| Sep 30, 2024 | -53.38 Mn |
| Jun 30, 2024 | -96.01 Mn |
| Jun 30, 2024 | -96.01 Mn |
| Mar 31, 2024 | -115.77 Mn |
| Mar 31, 2024 | -115.77 Mn |
| Dec 31, 2023 | -111.60 Mn |
| Dec 31, 2023 | -111.60 Mn |